Date published: 2025-9-11

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Hep B preS1 抗体 (AP2): sc-57762

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说明书
  • Hep B preS1抗体(AP2)是小鼠单克隆IgG2b κ, 在11篇文献中引用,规格为200 µg/ml
  • 针对Hep B preS1
  • 推荐用于 Hep B 来源的preS1 region WB, IP, IF 和 IHC(P)检测
  • 看 Hep B preS1 (AP1): sc-57761,可查看有标记的 Hep B preS1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG2b BP-HRPm-IgGκ BP-HRP 是 Hep B preS1 抗体 (AP2) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Hep B preS1 抗体 (AP2) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

乙型肝炎(Hep B)病毒是肝去氧核糖核酸病毒科的一员,可引起肝脏炎症、呕吐、黄疸,有时还会导致死亡。乙型肝炎是少数已知使用逆转录复制其基因组的非逆转录病毒之一。乙型肝炎病毒(HBV)由三种主要抗原组成。这三种抗原包括:表面抗原(乙型肝炎sAg,preS1/preS2),一种包膜糖蛋白,在乙型肝炎病毒感染者的血清中以膜状聚集体形式存在;e抗原(乙型肝炎eAg),通常与更高的病毒复制率相关;以及核心抗原(乙型肝炎cAg),它包围着病毒基因组,并构成衣壳蛋白的组装和未组装变体。乙型肝炎cAg和乙型肝炎eAg主要用于HBV诊断,而乙型肝炎sAg则用于疫苗中的HBV预防。乙型肝炎病毒抗原主要在肝脏中表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Hep B preS1 抗体 (AP2) 参考文献:

  1. 用免疫测定法检测乙肝患者康复所需的抗前 S1 抗体。  |  Wei, J., et al. 2002. World J Gastroenterol. 8: 276-81. PMID: 11925607
  2. 乙型肝炎病毒 PreS1 肽的表达及其多克隆抗体的制备。  |  Chen, W., et al. 2011. Hybridoma (Larchmt). 30: 525-30. PMID: 22149277
  3. 利用 preS1 肽分子配体靶向递送 siRNA 抗乙型肝炎病毒。  |  Huang, W., et al. 2014. Hepatol Res. 44: 897-906. PMID: 23799901
  4. 乙型肝炎病毒 preS1 缺失与病毒复制增加和疾病进展有关。  |  Lee, SA., et al. 2015. World J Gastroenterol. 21: 5039-48. PMID: 25945020
  5. 前 S1 结合肽有效抑制乙型肝炎病毒感染  |  Ye, X., et al. 2016. Sci Rep. 6: 29391. PMID: 27384014
  6. N终止子PreS1序列调控细胞培养产生的乙型肝炎病毒的高效感染。  |  Murayama, A., et al. 2021. Hepatology. 73: 520-532. PMID: 32446278
  7. TIMM29 与乙型肝炎病毒 preS1 相互作用,调节 HBV 生命周期。  |  Muriungi, NG. and Ueda, K. 2020. Microbiol Immunol. 64: 792-809. PMID: 32970362
  8. 血清 PreS1 和 HBsAg 比值反映了肝纤维化的情况,并可预测慢性乙型肝炎患者肝细胞癌的发展。  |  Nishida, Y., et al. 2021. J Viral Hepat. 28: 1304-1311. PMID: 34105859
  9. 5' preS1 突变可阻止乙型肝炎病毒 A 基因型或 D 基因型的大包膜蛋白表达,显著增加聚合酶-包膜融合蛋白。  |  Zhang, J., et al. 2022. J Virol. 96: e0172321. PMID: 35019714
  10. 前 S1 评估在慢性乙型肝炎病毒感染管理中的影响。  |  Hayashi, Y., et al. 2024. Medicina (Kaunas). 60: PMID: 39202615

订购信息

产品名称产品编号规格价格数量收藏夹

Hep B preS1 抗体 (AP2)

sc-57762
200 µg/ml
$316.00

Hep B preS1 (AP2): m-IgGκ BP-HRP 套装

sc-534335
200 µg Ab; 40 µg BP
$354.00

Hep B preS1 (AP2): m-IgG2b BP-HRP 套装

sc-549247
200 µg Ab; 10 µg BP
$354.00

Which epitope does this sc-57761 and sc-57762 recognize? Do you have any data on its cross-reactivity against other HepB strains?

Asked by: Sugata
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2022-09-07

What is the recommended secondary for Hep B preS1 (AP2): sc-57762 monoclonal antibody?

Asked by: Trav11
Thank you for your question. We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support
Date published: 2017-03-07
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Rated 4 out of 5 by from NiceNice, crisp band seen in WB using recombinant Hep B preS1. -SCBT QC
Date published: 2015-04-09
Rated 3 out of 5 by from Publishable data in WB using human Huh7Publishable data in WB using human Huh7, HepG2 and HEK 239T cells. -SCBT Publication Review
Date published: 2015-02-27
Rated 3 out of 5 by from Publishable data in IP using human Huh7Publishable data in IP using human Huh7, HepG2 and HEK 239T cells. -SCBT Publication Review
Date published: 2013-08-25
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Hep B preS1 抗体 (AP2) is rated 3.3 out of 5 by 3.
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