Date published: 2025-9-7

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CD44 抗体 (P2A1): sc-53298

4.8(6)
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说明书
  • CD44抗体(P2A1)是小鼠单克隆IgG2a κ, 在8篇文献中引用,规格为200 µg/ml
  • 针对眼黑色素瘤细胞系(V+B2)
  • 推荐用于 human 来源的HCAM WB, IP, IF, IHC(P) 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 CD44 (DF1485): sc-7297,可查看有标记的 CD44 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRPm-IgGκ BP-HRP 是 CD44 抗体 (P2A1) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与CD44 抗体 (P2A1) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

细胞黏附分子(CAMs)是一组密切相关的细胞表面糖蛋白,参与细胞与细胞之间的相互作用,在胚胎发生和发育中发挥重要作用。HCAM又称CD44、LHR、MDU2、MDU3、MIC4、Pgp1、HCELL、MUTCH-I或ECMR-III,是一种由742个氨基酸组成的单通道I型膜蛋白,参与造血、淋巴细胞活化和肿瘤转移。HCAM作为透明质酸(HA)的受体,与骨桥蛋白(OPN)等配体相互作用,介导细胞间和细胞-基质间的相互作用,从而在细胞黏附和细胞迁移中发挥重要作用。HCAM包含一个Link结构域,由于选择性剪接事件,HCAM被表达为多种亚型,其中一些被命名为CD44R, CDw44, CD44S, CD44H(造血)和CD44E(上皮)。虽然大多数HCAM剪接变异体在全身组织中都有表达,但有一种特殊的异构体,即CD44H,在癌组织中高水平表达,这表明CD44H剪接变异体在肿瘤进展中发挥重要作用。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

CD44 抗体 (P2A1)

sc-53298
200 µg/ml
$316.00

CD44 (P2A1): m-IgG Fc BP-HRP 套装

sc-536929
200 µg Ab; 10 µg BP
$354.00

CD44 (P2A1): m-IgGκ BP-HRP 套装

sc-534104
200 µg Ab; 40 µg BP
$354.00

CD44 (P2A1): m-IgG2a BP-HRP 套装

sc-547902
200 µg Ab; 10 µg BP
$354.00

CD44 抗体 (P2A1) FITC

sc-53298 FITC
200 µg/ml
$330.00

CD44 抗体 (P2A1) PE

sc-53298 PE
200 µg/ml
$343.00

anti-CD44 (HCAM-P2A1:sc53298) from Santa Cruz biotechnology, is a monoclonal antibody against CD44 raised against wild-type CD44 or a total antibody that detects other CD44 variants?

Asked by: Trupti Trivedi
Thank you for your question. sc-53298 HCAM (P2A1) has not been epitope mapped. Here is a link for more information on the protein : https://www.uniprot.org/uniprotkb/P16070/entry#sequences
Answered by: BlakeJ
Date published: 2024-08-01

Can HCAM (P2A1): sc-53298 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Trav11
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, HCAM (P2A1): sc-53298 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Excellent!This antibody works great in western blot analysis of HCAM expression in HUV-EC-C, human PBL, HeLa and WI 38 whole cell lysates.
Date published: 2017-01-19
Rated 4 out of 5 by from Robust bands detected in western blot analysisRobust bands detected in western blot analysis of HCAM expression in HeLa, U-937, human PBL, HUV-EC-C and CCRF-CEM whole cell lysates. -SCBT QC
Date published: 2015-04-20
Rated 5 out of 5 by from Exceptional immunoperoxidase membrane andExceptional immunoperoxidase membrane and cytoplasmic staining in formalin fixed, paraffin-embedded human esophagus tissue. -SCBT QC
Date published: 2015-03-16
Rated 5 out of 5 by from Published immunohistochemical analysis ofPublished immunohistochemical analysis of HCAM in human brain, leptomeninges, spinal cord and eye sections. -SCBT Publication Review
Date published: 2015-01-24
Rated 5 out of 5 by from Strong bands representing HCAM present inStrong bands representing HCAM present in western blot when using HUV-EC-C, human PBL, HeLa and WI 38 whole cell lysates. -SCBT QC
Date published: 2015-01-20
Rated 5 out of 5 by from Produced superb indirect FCM data for humanProduced superb indirect FCM data for human peripheral blood leukocytes stained with HCAM . -SCBT QC
Date published: 2013-06-25
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CD44 抗体 (P2A1) is rated 4.8 out of 5 by 6.
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