Anticorps GRASP65 (B-3): sc-398363
- L'Anticorps GRASP65 (B-3) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 2-29 au niveau N-terminus de GRASP65 d'origine human
- recommandé pour la détection de GRASP65 d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps GRASP65 (B-3) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps GRASP65 (B-3)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, the golgins and other peripheral membrane components such as GRASP55 and GRASP65. GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery. GRASP55 is highly homologous to GRASP65 and contains two PDZ domains. GRASP55 is myristoylated and palmitoylated. Unlike GRASP65, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi. Both GRASP55 and GRASP65 function in the stacking of Golgi cisternae. The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure. ERK2 directly phosphorylates GRASP55, which is phosphorylated in mitotic cells, suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps GRASP65 (B-3) | sc-398363 | 200 µg/ml | $322.00 | |||
GRASP65 (B-3): m-IgG Fc BP-HRP Kit | sc-538426 | 200 µg Ab; 10 µg BP | $361.00 | |||
GRASP65 (B-3): m-IgGκ BP-HRP Kit | sc-536039 | 200 µg Ab; 40 µg BP | $361.00 | |||
GRASP65 (B-3): m-IgG2a BP-HRP Kit | sc-548297 | 200 µg Ab; 10 µg BP | $361.00 | |||
GRASP65 (B-3) peptide neutralisant | sc-398363 P | 100 µg/0.5 ml | $69.00 |