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Filamin 1 Antibody (PM6/317) - Western Blotting - Image 57647
Filamin 1 抗体 (PM6/317): sc-58764. Filamin 1 在 HeLa (A) 和 U-87 MG (B) 全细胞裂解液中的表达的 Western 印迹分析.
Filamin 1 抗体 (PM6/317): sc-58764. Filamin 1 在 HeLa (A) 和 U-87 MG (B) 全细胞裂解液中的表达的 Western 印迹分析.

Filamin 1 抗体 (PM6/317): sc-58764

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说明书
  • Filamin 1抗体(PM6/317)是小鼠单克隆IgG1 κ, 在8篇文献中引用，规格为200 µg/ml
  • 针对全长血小板Filamin 1的human来源
  • 推荐用于 mouse, rat 和 human 来源的Filamin 1 from platelets, lymphocytes, fibroblasts and smooth muscle WB, IP, IF, IHC(P) 和 ELISA检测
  • 看 Filamin 1 (E-3): sc-17749，可查看有标记的 Filamin 1 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP和 m-IgG1 BP-HRP是Filamin 1 Antibody (PM6/317) for WB and IHC(P) applications. 的首选辅助检测试剂，这些试剂现与Filamin 1 Antibody (PM6/317) 打包提供（请参阅下面的订购信息）。
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関連項目

额外Filamin抗体，包括Filamin 3

Caldesmon、Filamin 1、Nebulin和Villin是差异表达和调节的肌动蛋白结合蛋白。肌性（CDh）和非肌性（CDl）形式的Caldesmon已被鉴定，每种形式都被证明与肌动蛋白、钙调素和肌球蛋白结合。CDh主要在平滑肌的细丝上表达，而CDl在非肌肉组织和细胞中广泛表达。Filamin 1以同二聚体形式广泛表达，其功能是将肌动蛋白与细丝交联。Nebulin是一种肌肉组织特异性的大型丝状蛋白，可能作为细丝长度的标尺。Nebulin的几种异构体是通过外显子的交替使用产生的。Villin受Ca2+调节，是吸收细胞刷状缘的主要结构成分。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Filamin 1 抗体 (PM6/317) 参考文献:

  1. [作为癌细胞变化介质的纤 维素 A］  |  Wieczorek, K. and Niewiarowska, J. 2014. Postepy Biochem. 60: 77-83. PMID: 25033545
  2. 皮质营养瘤中丝胶 A 和 DRD2 的表达。  |  Sickler, T., et al. 2019. Pituitary. 22: 163-169. PMID: 30799513
  3. 甲状旁腺癌中丝胶素 A 和副丝胶素的表达  |  Storvall, S., et al. 2021. Eur J Endocrinol. 185: 803-812. PMID: 34606470
  4. 喉鳞状细胞癌中Filamin-A的表达及其临床意义  |  Ouban, A. 2022. Histol Histopathol. 37: 125-136. PMID: 34677823
  5. 小鼠平滑肌细胞中丝胶素 A 的缺乏可防止缺氧介导的肺动脉高压。  |  Zheng, Y., et al. 2023. Int J Mol Med. 51: PMID: 36704846
  6. 依赖于力的丝胶素 A-G3BP1 相互作用调控相分离应激颗粒的形成。  |  Feng, Z., et al. 2023. J Cell Sci. 136: PMID: 36806943
  7. 丝胺 A-Sav1 相互作用在器官大小控制中的重要性：来自转基因小鼠的证据。  |  Zhang, H., et al. 2023. Int J Dev Biol. 67: 27-37. PMID: 37548015
  8. 长链非编码RNA LINC01569通过海绵状miR-300上调丝胶素A互作蛋白1-like以防止三阴性乳腺癌转移  |  Jiang, X., et al. 2024. Cancer Biomark. 39: 79-94. PMID: 37955081
  9. 丝胶素 A 与人类肝内胆管癌的侵袭性和进展有关。  |  Vitali, E., et al. 2024. Liver Int. 44: 518-531. PMID: 38010911
  10. 作为遗传性双尖瓣和三尖瓣主动脉瓣病遗传原因的纤 维素 A 心脏瓣膜病  |  Delwarde, C., et al. 2024. Heart. 110: 666-674. PMID: 38148157

订购信息

产品名称产品编号规格价格数量收藏夹

Filamin 1 抗体 (PM6/317)

sc-58764
200 µg/ml
$322.00

Filamin 1 (PM6/317): m-IgG Fc BP-HRP 套装

sc-539098
200 µg Ab; 10 µg BP
$361.00

Filamin 1 (PM6/317): m-IgG1 BP-HRP 套装

sc-541257
200 µg Ab; 20 µg BP
$361.00

Can I have a small sample for Free to try on IF and WB on hESCs ? Many thanks in advance, Irina

Asked by: IrinaNeganova
Thank you for your question. Please contact Technical Service for information on how to obtain a sample.
Answered by: SCBT Heidelberg Support
Date published: 2018-12-14

I am using Filamin 1 (PM6/317): sc-58764 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: Professor Griffin
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by vigas from One of the best antibodiesI use this antibody in my ELISA experiment,i got good data.
Date published: 2017-04-30
Rated 5 out of 5 by DefinitelyNotMatt from Very Versatile AntibodyThis antibody is well-cited for a variety of applications including WB, IP, IF, and even IHC and ELISA. Strong, clear signal with little to no background. Beautiful tissue staining. Works well in a variety of species including mouse, rat, and human samples.
Date published: 2017-02-08
Rated 4 out of 5 by HF from Produced clear immunoperoxidase cytoplasmicProduced clear immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human smooth muscle tissue. -SCBT QC
Date published: 2015-05-17
Rated 4 out of 5 by JL from IF with paraformaldehyde fixed HeLa and CHO cellsIF with paraformaldehyde fixed HeLa and CHO cells. -SCBT Publication Review
Date published: 2015-05-12
Rated 4 out of 5 by CJ from CoIP/WB and IF data published using mouseCoIP/WB and IF data published using mouse embryo cortex & A7 melanoma. -SCBT Publication Review
Date published: 2015-04-04
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Filamin 1 抗体 (PM6/317) is rated 4.4 out of 5 by 5.
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