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FGF-10 Antibody (3C7): sc-293208

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Datasheets
  • FGF-10 Antibody (3C7) is a mouse monoclonal IgG2a κ FGF-10 antibody, cited in 1 publications, provided at 100 µg/ml
  • raised against amino acids 38-137 of FGF-10 of human origin
  • recommended for detection of FGF-10 of human origin by WB, IP and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for FGF-10 Antibody (3C7). This work is in progress.
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FGF-10 Antibody (3C7) is a mouse monoclonal IgG2a kappa light chain antibody that detects FGF-10 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-FGF-10 antibody (3C7) is available as a non-conjugated format. FGF-10 plays a crucial role in various biological processes, including embryonic development, tissue repair, and regulation of cell proliferation and differentiation. FGF-10 is primarily located in mesenchyme and is essential for development of organs such as lungs and limbs. Disruptions in FGF-10 signaling pathways can lead to developmental disorders and contribute to diseases such as cancer. FGF-10 interacts with specific receptors, including fibroblast growth factor receptor 2 (FGFR2), which mediates biological effects, highlighting FGF-10′s importance in cellular communication and signaling pathways.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

FGF-10 Antibody (3C7) References:

  1. Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells.  |  Tanaka, A., et al. 1992. Proc Natl Acad Sci U S A. 89: 8928-32. PMID: 1409588
  2. Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.  |  Dionne, CA., et al. 1990. EMBO J. 9: 2685-92. PMID: 1697263
  3. Recent developments in the cell biology of basic fibroblast growth factor.  |  Rifkin, DB. and Moscatelli, D. 1989. J Cell Biol. 109: 1-6. PMID: 2545723
  4. Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family.  |  Marics, I., et al. 1989. Oncogene. 4: 335-40. PMID: 2649847
  5. Fibroblast Growth Factor-10 (FGF-10) Mobilizes Lung-resident Mesenchymal Stem Cells and Protects Against Acute Lung Injury.  |  Tong, L., et al. 2016. Sci Rep. 6: 21642. PMID: 26869337
  6. An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family.  |  Delli Bovi, P., et al. 1987. Cell. 50: 729-37. PMID: 2957062
  7. Sequence, topography and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammary tumour virus.  |  Moore, R., et al. 1986. EMBO J. 5: 919-24. PMID: 3013624
  8. The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors.  |  Zhan, X., et al. 1988. Mol Cell Biol. 8: 3487-95. PMID: 3211147
  9. FGF 10 Inhibited Spinal Microglial Activation in Neuropathic Pain via PPAR-γ/NF-κB Signaling.  |  Bian, J., et al. 2022. Neuroscience. 500: 52-62. PMID: 35934252
  10. Focal sources of FGF-10 promote the buckling morphogenesis of the embryonic airway epithelium.  |  Peak, KE., et al. 2022. Biol Open. 11: PMID: 35979841
  11. Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property.  |  Miyamoto, M., et al. 1993. Mol Cell Biol. 13: 4251-9. PMID: 8321227
  12. Mouse fibroblast growth factor 10: cDNA cloning, protein characterization, and regulation of mRNA expression.  |  Beer, HD., et al. 1997. Oncogene. 15: 2211-8. PMID: 9393979

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

FGF-10 Antibody (3C7)

sc-293208
100 µg/ml
$322.00

Hello. For sc-293208, was as the immunogen used FGF10 recombinant protein with or without GST tag? I am asking because I found antibody with the same name "FGF10-antibody (C37)" in different company and this antibody was with GST-tag.

Asked by: NikolaPt
Thank you for your question. Unfortunately we do not provide this information, however standard procedure for monoclonal antibody production using a recombinant protein does include GST conjugation (and GST subtraction later in the process).
Answered by: Tech Service
Date published: 2019-09-26

For Western Blot, is it recommended to use denatured or non-denatured conditions with FGF-10 (3C7): sc-293208 antibody?

Asked by: DefinitelyNotMatt
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by from Can use for immunoperoxidase staining[Employee of scbt] Antibody has been used to detect FGF-10 in IPNB (intraductal papillary neoplasm of the bile duct) tumor cells by immunoperoxidase staining. -SCBT QC
Date published: 2023-09-14
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FGF-10 Antibody (3C7) is rated 5.0 out of 5 by 1.
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