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FGF-10 抗体 (3C7): sc-293208

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说明书
  • FGF-10 抗体 3C7 是小鼠单克隆 IgG2a κ,FGF-10抗体, 在1篇文献中引用,规格为100 µg/ml
  • 免疫human物种的FGF-10的氨基酸38-137
  • 推荐用于 human 来源的FGF-10 WB, IP 和 ELISA检测
  • 目前,我们还没有完成FGF-10 抗体 (3C7)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

FGF-10抗体(3C7)是一种小鼠单克隆IgG2a kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)和酶联免疫吸附测定(ELISA)检测人源FGF-10蛋白。抗FGF-10抗体(3C7)以非结合形式提供。FGF-10在胚胎发育、组织修复、细胞增殖和分化调节等多种生物过程中发挥着关键作用。FGF-10主要位于间质中,对于肺和四肢等器官的发育至关重要。FGF-10信号传导通路紊乱会导致发育障碍,并诱发癌症等疾病。FGF-10与特定的受体相互作用,包括成纤维细胞生长因子受体2(FGFR2),后者可调节生物学效应,凸显了FGF-10在细胞通讯和信号传导通路中的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

FGF-10 抗体 (3C7) 参考文献:

  1. 小鼠乳腺癌细胞依赖雄激素生长所必需的雄激素诱导生长因子的克隆和特征描述。  |  Tanaka, A., et al. 1992. Proc Natl Acad Sci U S A. 89: 8928-32. PMID: 1409588
  2. 克隆和表达与酸性和碱性成纤维细胞生长因子交叉反应的两种不同的高亲和力受体。  |  Dionne, CA., et al. 1990. EMBO J. 9: 2685-92. PMID: 1697263
  3. 碱性成纤维细胞生长因子细胞生物学的最新发展。  |  Rifkin, DB. and Moscatelli, D. 1989. J Cell Biol. 109: 1-6. PMID: 2545723
  4. 成纤维细胞生长因子家族新成员--与 HST 相关的 FGF.6 基因的特征。  |  Marics, I., et al. 1989. Oncogene. 4: 335-40. PMID: 2649847
  5. 成纤维细胞生长因子-10 (FGF-10) 调动肺驻留间充质干细胞并保护肺免受急性损伤  |  Tong, L., et al. 2016. Sci Rep. 6: 21642. PMID: 26869337
  6. 通过转染卡波西肉瘤 DNA 分离出的癌基因编码一种生长因子,属于 FGF 家族。  |  Delli Bovi, P., et al. 1987. Cell. 50: 729-37. PMID: 2957062
  7. 小鼠 int-2 的序列, 拓扑结构和蛋白质编码潜力:一种由小鼠乳腺肿瘤病毒激活的假定癌基因。  |  Moore, R., et al. 1986. EMBO J. 5: 919-24. PMID: 3013624
  8. 人类 FGF-5 癌基因编码一种与成纤维细胞生长因子有关的新型蛋白质。  |  Zhan, X., et al. 1988. Mol Cell Biol. 8: 3487-95. PMID: 3211147
  9. FGF 10通过PPAR-γ/NF-κB信号抑制神经病理性疼痛中脊髓小胶质细胞的活化  |  Bian, J., et al. 2022. Neuroscience. 500: 52-62. PMID: 35934252
  10. FGF-10 的局部来源促进了胚胎气道上皮细胞的屈曲形态发生。  |  Peak, KE., et al. 2022. Biol Open. 11: PMID: 35979841
  11. 编码成纤维细胞生长因子家族第九个成员的新型细胞因子 cDNA 的分子克隆,该细胞因子具有独特的分泌特性。  |  Miyamoto, M., et al. 1993. Mol Cell Biol. 13: 4251-9. PMID: 8321227
  12. 小鼠成纤维细胞生长因子 10:cDNA 克隆, 蛋白质鉴定和 mRNA 表达调控。  |  Beer, HD., et al. 1997. Oncogene. 15: 2211-8. PMID: 9393979

订购信息

产品名称产品编号规格价格数量收藏夹

FGF-10 抗体 (3C7)

sc-293208
100 µg/ml
$316.00

Hello. For sc-293208, was as the immunogen used FGF10 recombinant protein with or without GST tag? I am asking because I found antibody with the same name "FGF10-antibody (C37)" in different company and this antibody was with GST-tag.

Asked by: NikolaPt
Thank you for your question. Unfortunately we do not provide this information, however standard procedure for monoclonal antibody production using a recombinant protein does include GST conjugation (and GST subtraction later in the process).
Answered by: Tech Service
Date published: 2019-09-26

For Western Blot, is it recommended to use denatured or non-denatured conditions with FGF-10 (3C7): sc-293208 antibody?

Asked by: DefinitelyNotMatt
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by from Can use for immunoperoxidase stainingAntibody has been used to detect FGF-10 in IPNB (intraductal papillary neoplasm of the bile duct) tumor cells by immunoperoxidase staining. -SCBT QC
Date published: 2023-09-14
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FGF-10 抗体 (3C7) is rated 5.0 out of 5 by 1.
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