Date published: 2025-9-7

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FBXO22 抗体 (FF-7): sc-100736

5.0(4)
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说明书
  • FBXO22 抗体 FF-7 是小鼠单克隆 IgG1 κ,FBXO22抗体, 在4篇文献中引用,规格为100 µg/ml
  • 免疫human物种的重组FBXO22
  • 推荐用于 human 来源的FBXO22 WB, IP 和 ELISA检测
  • 关于如何获取FBXO22 (FF-7): sc-100736免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是FBXO22 Antibody (FF-7) for WB applications. 的首选辅助检测试剂,这些试剂现与FBXO22 Antibody (FF-7) 打包提供(请参阅下面的订购信息)。

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関連項目

FBXO22抗体(FF-7)是一种IgG1 κ小鼠单克隆FBXO22抗体(也称为FBX22抗体),可通过WB、IP和ELISA检测人源的FBXO22蛋白。FBXO22抗体(FF-7)可作为非偶联的抗FBXO22抗体使用。FBXO22(仅含F-box的蛋白22),也称为FBX22或FBX22p44,是一种含有403个氨基酸的蛋白质,主要在肝脏中表达。F-box蛋白质是SCF(Skp1-CUL-1-F-box蛋白质)型E3泛素连接酶复合物的关键组成部分,参与底物识别和泛素化招募。它们是更大的蛋白质家族成员,参与调节多种细胞过程(包括细胞周期、免疫反应、信号级联和发育过程),通过靶向蛋白质,如细胞周期蛋白和细胞周期蛋白依赖性激酶抑制剂(CDKNs)、IkB-α和β-连环蛋白,在泛素化后被蛋白酶体降解。由于选择性剪接,存在三种FBXO22异构体。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

FBXO22 抗体 (FF-7) 参考文献:

  1. 人类 F-box 蛋白家族的鉴定。  |  Cenciarelli, C., et al. 1999. Curr Biol. 9: 1177-9. PMID: 10531035
  2. 哺乳动物 F-box 蛋白家族。  |  Winston, JT., et al. 1999. Curr Biol. 9: 1180-2. PMID: 10531037
  3. 哺乳动物 F-box 蛋白的系统分析和命名。  |  Jin, J., et al. 2004. Genes Dev. 18: 2573-80. PMID: 15520277
  4. Pin1 通过阻止 Emi1 与 SCF(betatrcp)结合,在 G2 期稳定 Emi1。  |  Bernis, C., et al. 2007. EMBO Rep. 8: 91-8. PMID: 17159919
  5. F盒蛋白S期激酶缔合作用蛋白2调节体内脂肪量和脂肪细胞数量。  |  Cooke, PS., et al. 2007. Obesity (Silver Spring). 15: 1400-8. PMID: 17557977
  6. 含有糖结合结构域的 F-box 蛋白。  |  Yoshida, Y. 2007. Biosci Biotechnol Biochem. 71: 2623-31. PMID: 17986767

订购信息

产品名称产品编号规格价格数量收藏夹

FBXO22 抗体 (FF-7)

sc-100736
100 µg/ml
$333.00

FBXO22 (FF-7): m-IgG Fc BP-HRP 套装

sc-539707
100 µg Ab; 10 µg BP
$354.00

FBXO22 (FF-7): m-IgG1 BP-HRP 套装

sc-541663
100 µg Ab; 20 µg BP
$354.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with FBXO22 (FF-7): sc-100736 antibody?

Asked by: Germaine
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by from Good for Western BlotThis antibody has been used for western blot in published research. -SCBT QC
Date published: 2023-09-14
Rated 5 out of 5 by from Good specificity in WB in HeLa nuclear extractGood specificity in WB in HeLa nuclear extract. -SCBT QC
Date published: 2015-02-24
Rated 5 out of 5 by from Robust signal in WB in human transfectedRobust signal in WB in human transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-01-28
Rated 5 out of 5 by from Strong band in WB in human transfected 293TStrong band in WB in human transfected 293T and T1 whole cell lysates. -SCBT QC
Date published: 2014-02-03
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FBXO22 抗体 (FF-7) is rated 5.0 out of 5 by 4.
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