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Ezrin 抗体 (F-1): sc-377205

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说明书
  • Ezrin抗体(F-1)是小鼠单克隆IgG1 κ, 在1篇文献中引用,规格为200 µg/ml
  • 免疫human物种的Ezrin的氨基酸311-586
  • 推荐用于 human 来源的Ezrin WB, IP, IF, IHC(P) 和 ELISA检测
  • 看 Ezrin (3C12): sc-58758,可查看有标记的 Ezrin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP和 m-IgG1 BP-HRP是Ezrin Antibody (F-1) for WB and IHC(P) applications. 的首选辅助检测试剂,这些试剂现与Ezrin Antibody (F-1) 打包提供(请参阅下面的订购信息)。
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関連項目

Ezrin、Moesin和Radixin属于高同源肌动蛋白相关蛋白家族,仅位于质膜之下。这些蛋白质被认为参与介导细胞骨架和膜蛋白之间的相互作用。Ezrin是各种蛋白酪氨酸激酶的主要细胞质底物,包括表皮生长因子受体。Ezrin也被鉴定为cAMP依赖性蛋白激酶(A激酶)锚定蛋白,并被命名为AKAP78。Moesin和Radixin与Ezrin具有70%以上的同源性,并在各种细胞类型中共同表达。尽管同源性很高,但这三种蛋白质表现出独特的受体特异性磷酸化模式。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Ezrin 抗体 (F-1) 参考文献:

  1. Ezrin-Radixin-Moesin蛋白家族对大脑皮层结构的调控  |  Bretscher, A. 1999. Curr Opin Cell Biol. 11: 109-16. PMID: 10047517
  2. Ezrin是Rap1诱导细胞有效扩散所必需的。  |  Ross, SH., et al. 2011. J Cell Sci. 124: 1808-18. PMID: 21540295
  3. 在培养的大脑皮质神经元中,Ezrin通过下调RhoA活性介导神经元的发生。  |  Matsumoto, Y., et al. 2014. PLoS One. 9: e105435. PMID: 25144196
  4. Ezrin 与支架蛋白 IQGAP1 相互作用,并影响其皮层定位。  |  Nammalwar, RC., et al. 2015. Biochim Biophys Acta. 1853: 2086-94. PMID: 25554515
  5. ezrin敲除对胃腺上皮结构的影响。  |  Yoshida, S., et al. 2016. J Physiol Sci. 66: 53-65. PMID: 26329936
  6. 宫颈癌发生过程中 Ezrin 和雌激素受体的表达  |  Fadiel, A., et al. 2017. Reprod Sci. 24: 706-712. PMID: 27688241
  7. 曲面上Ezrin富集需要特定的构象或与曲率敏感的伴侣相互作用。  |  Tsai, FC., et al. 2018. Elife. 7: PMID: 30234483
  8. 抑制Ezrin可抑制人鼻咽癌细胞的迁移和侵袭。  |  Tang, Y., et al. 2019. Oncol Lett. 18: 553-560. PMID: 31289527
  9. Moesin和Ezrin作为早期检测子宫内膜癌的新标记物:一项免疫组化研究  |  Salama, MEM. and Khairy, DA. 2023. Asian Pac J Cancer Prev. 24: 3243-3246. PMID: 37774078
  10. Ezrin 具有在质膜上自我结合的特性。  |  Andréoli, C., et al. 1994. J Cell Sci. 107 (Pt 9): 2509-21. PMID: 7844168

订购信息

产品名称产品编号规格价格数量收藏夹

Ezrin 抗体 (F-1)

sc-377205
200 µg/ml
$322.00

Ezrin (F-1): m-IgG Fc BP-HRP 套装

sc-540701
200 µg Ab; 10 µg BP
$361.00

Ezrin (F-1): m-IgG1 BP-HRP 套装

sc-542309
200 µg Ab; 20 µg BP
$361.00

I am using Ezrin (F-1): sc-377205 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: jenniferc
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by JM from Strong band see in WB in HeLa and Ramos wholeStrong band see in WB in HeLa and Ramos whole cell lysates. -SCBT QC
Date published: 2015-06-01
Rated 5 out of 5 by HF from Excellent immunoperoxidase cytoplasmic andExcellent immunoperoxidase cytoplasmic and membrane staining in formalin fixed, paraffin-embedded human tonsil tissue. -SCBT QC
Date published: 2015-03-18
Rated 5 out of 5 by TS from Positive signal observed in WB in nonPositive signal observed in WB in non-transfected 293T, human Ezrin transfected 293T and Jurkat whole cell lysates. -SCBT QC
Date published: 2015-03-06
Rated 5 out of 5 by MC from Good specificity in WB in RamosGood specificity in WB in Ramos, MCF7 and K-562 whole cell lysates. -SCBT QC
Date published: 2015-02-02
Rated 5 out of 5 by CJ from Published data for WB in mouse brainPublished data for WB in mouse brain. -SCBT Publication Review
Date published: 2015-01-26
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Ezrin 抗体 (F-1) is rated 5.0 out of 5 by 5.
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