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Ezrin 抗体 (5G110): sc-71081

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说明书
  • Ezrin抗体(5G110)是小鼠单克隆IgG1 κ, 在1篇文献中引用,规格为200 µg/ml
  • 免疫human物种的Ezrin的氨基酸362-585
  • 推荐用于 mouse, rat, human 和 bovine 来源的Ezrin WB, IP, IF 和 IHC(P)检测
  • 看 Ezrin (3C12): sc-58758,可查看有标记的 Ezrin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP和 m-IgG1 BP-HRP是Ezrin Antibody (5G110) for WB and IHC(P) applications. 的首选辅助检测试剂,这些试剂现与Ezrin Antibody (5G110) 打包提供(请参阅下面的订购信息)。
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関連項目

Ezrin、Moesin和Radixin属于高同源肌动蛋白相关蛋白家族,仅位于质膜之下。这些蛋白质被认为参与介导细胞骨架和膜蛋白之间的相互作用。Ezrin是各种蛋白酪氨酸激酶的主要细胞质底物,包括表皮生长因子受体。Ezrin也被鉴定为cAMP依赖性蛋白激酶(A激酶)锚定蛋白,并被命名为AKAP78。Moesin和Radixin与Ezrin具有70%以上的同源性,并在各种细胞类型中共同表达。尽管同源性很高,但这三种蛋白质表现出独特的受体特异性磷酸化模式。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Ezrin 抗体 (5G110) 参考文献:

  1. FAS介导的细胞凋亡中FAS与ezrin结合的作用。  |  Fais, S., et al. 2005. Apoptosis. 10: 941-7. PMID: 16151629
  2. 骨肉瘤中Ezrin免疫表达的预后作用:已发表数据的荟萃分析。  |  Li, H., et al. 2013. PLoS One. 8: e64513. PMID: 23805177
  3. Epac1和ezrin在控制内皮屏障功能方面的相互作用。  |  Parnell, E. and Yarwood, SJ. 2014. Biochem Soc Trans. 42: 274-8. PMID: 24646230
  4. Ezrin通过调节AKT信号促进乳腺癌进展。  |  Li, N., et al. 2019. Br J Cancer. 120: 703-713. PMID: 30804430
  5. 光响应微RNA miR-211靶向Ezrin,调节溶酶体的生物生成和视网膜细胞的清除。  |  Naso, F., et al. 2020. EMBO J. 39: e102468. PMID: 32154600
  6. Ezrin保护牛精子免受自发顶体反应的影响。  |  Huta, Y., et al. 2020. Theriogenology. 151: 119-127. PMID: 32334120
  7. 作为预后指标的Ezrin通过糖酵解调节结肠腺癌的进展。  |  Wang, Y., et al. 2021. J Gastroenterol Hepatol. 36: 710-720. PMID: 32710796
  8. Ezrin 促进卵巢癌细胞的增殖、迁移和侵袭。  |  Li, MJ., et al. 2021. Biomed Environ Sci. 34: 139-151. PMID: 33685573
  9. Ezrin有助于A2780细胞质膜表达PD-L1。  |  Tameishi, M., et al. 2022. J Clin Med. 11: PMID: 35566582
  10. 感染幽门螺杆菌的家猫胃细胞中的Ezrin免疫表达。  |  Sousa, DA., et al. 2023. Res Vet Sci. 154: 84-88. PMID: 36512978

订购信息

产品名称产品编号规格价格数量收藏夹

Ezrin 抗体 (5G110)

sc-71081
200 µg/ml
$322.00

Ezrin (5G110): m-IgG Fc BP-HRP 套装

sc-539345
200 µg Ab; 10 µg BP
$361.00

Ezrin (5G110): m-IgG1 BP-HRP 套装

sc-541426
200 µg Ab; 20 µg BP
$361.00

Can Ezrin (5G110): sc-71081 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Trav11
Thank you for your question. Yes, Ezrin (5G110): sc-71081 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-28
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Rated 4 out of 5 by FL from Strong band of interest observed in WB in AStrong band of interest observed in WB in A-431 whole cell lysate. -SCBT QC
Date published: 2015-07-13
Rated 4 out of 5 by MS from Good specificity in WB in Jurkat and NIH/3T3Good specificity in WB in Jurkat and NIH/3T3 whole cell lysates. -SCBT QC
Date published: 2015-05-04
Rated 4 out of 5 by HC from Robust positive band observed in WB in nonRobust positive band observed in WB in non-transfected 293T, human Ezrin transfected 293T and Ramos whole cell lysates. -SCBT QC
Date published: 2014-02-01
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Ezrin 抗体 (5G110) is rated 4.0 out of 5 by 3.
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