EDTA, Disodium Salt, Dihydrate CAS: 6381-92-6
MF: C10H14N2Na2O8•2H2O
MW: 372.2
A chelating agent for metal ions; minimizes metal ion impurities in reaction buffers.

EDTA, Disodium Salt, Dihydrate (CAS 6381-92-6)

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同义词: Disodium ethylenediaminetetraacetatedihydrate;Edetatedisodium saltdihydrate
应用; A chelating agent for metal ions; minimizes metal ion impurities in reaction buffers
CAS号码: 6381-92-6
纯度: ≥99%
分子量: 372.2
分子式: C10H14N2Na2O82H2O
* 参考分析证明 大量特定数据 (包括水 含量).
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EDTA, Disodium Salt, Dihydrate is an extensively used chelator of divalent cations such as Ca2+. EDTA (Ethylenediaminetetraacetic acid) is a chelating agent, a general chemical, and a sequestrant. In molecular biology applications, it is used to minimize metal ion contaminants. Also used to facilitate enzymatic reactions that could be inhibited by heavy metal traces. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.


参考文献

1. Van Kley, H. and Claywell, C.S. 1973. Clin. Chem. 19: 621-623. PMID: 4196140

外观 :
Crystalline
物理状态 :
Solid
溶解度 :
Soluble in water (100 g/l) at 20 °C, and 3 M NaOH (100 mg/ml).
保存 :
Store at room temperature
熔点 :
250° C (lit.)(dec.)
沸点 :
>100° C
密度 :
1.01 g/cm3 at 25° C
折射率 :
n20D 1.36
pK值 :
pKa: 2.0, 2.7, 6.2, 10.3
仅供科研使用。不可用于诊断或治疗。
德国水公害等级 :
2
RTECS :
AH4375000
PubChem CID :
44120005
默克索引 :
14: 3517
MDL 号码 :
MFCD00150037
EC号码 :
205-358-3
Beilstein 注册 :
3900609
SMILES :
C(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)O)CC(=O)O.O.O.[Na+].[Na+]

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PMID: # 26211618  Wan, G. et al. 2015. Scientific reports. 5: 12527.

PMID: # 19805344  Sharma, H. et al. 2009. Proc. Natl. Acad. Sci. U.S.A. 106: 16604-16609.

PMID: # 19623194  Li, D. et al. 2009. J. Cereb. Blood Flow Metab. epub.

PMID: # 11839804  Kim, B.C. et al. 2002. Mol. Cell. Biol. 22(5): 1369-78.

PMID: # 11325813  Cusack, JC. et al. 2001. Cancer Res. 61: 3535-3540.

PMID: # 11306489  Hideshima, T. et al. 2001. Cancer Res. 61: 3071-3076.

PMID: # 10801895  Wakino, S et al. 2000. JBC. 275: 22435-22441.

PMID: # 10623846  Cario, E. et al. 2000. J. Immunol. 164: 966-972.

PMID: # 10535943  Hsu, HL. et al. 1999. Proc. Natl. Acad. Sci. U.S.A. 96: 12454-12458.

PMID: # 9660836  Favata, MF. et al. 1998. J. Biol. Chem. 273: 18623-18632.

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