Date published: 2025-9-7

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CTL2 抗体 (F7): sc-101266

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说明书
  • CTL2 抗体 F7 是小鼠单克隆 IgG1 (kappa轻链),CTL2抗体,规格为100 µg/ml
  • 免疫human物种的CTL2的氨基酸123-231
  • 推荐用于 mouse, rat 和 human 来源的CTL2 WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取CTL2 (F7): sc-101266免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 CTL2 抗体 (F7) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与CTL2 抗体 (F7) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

CTL2抗体(F7)是一种IgG1κ小鼠单克隆CTL2抗体,可通过WB、IP、IF、IHC(P)和ELISA检测来自小鼠、大鼠和人的CTL2蛋白。CTL2抗体(F7)为非偶联型抗CTL2抗体。胆碱是合成乙酰胆碱(一种在胆碱能神经末梢中发现的神经递质)和磷脂酰胆碱(细胞膜的关键成分)所必需的基本营养物质。胆碱缺乏与细胞生长缺陷有关,并已牵涉到阿尔茨海默病和帕金森病等疾病中。胆碱转运蛋白样蛋白家族(CTL)是溶质载体,可将不能渗透细胞的化合物胆碱转运穿过细胞膜。CTL2,也称为SLC44A2(溶质载体家族44成员2),是一种在内耳细胞中表达的多通道膜蛋白。CTL2可能是人类自身免疫性听力丧失的候选者。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CTL2 抗体 (F7) 参考文献:

  1. 酵母胆碱转运突变的电叶抑制因子属于一个新的转运体类蛋白家族。  |  O'Regan, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 1835-40. PMID: 10677542
  2. 胆碱转运体样蛋白 2 的鉴定和特征描述,这是一种 68 和 72 kDa 的内耳糖蛋白,是抗体诱导听力损失的靶标。  |  Nair, TS., et al. 2004. J Neurosci. 24: 1772-9. PMID: 14973250
  3. 胆碱转运体样蛋白家族及其剪接变体的分子特征。  |  Traiffort, E., et al. 2005. J Neurochem. 92: 1116-25. PMID: 15715662
  4. 胆碱运输用于磷脂合成。  |  Michel, V., et al. 2006. Exp Biol Med (Maywood). 231: 490-504. PMID: 16636297
  5. DFNB68,一个位于染色体 19p13.2 区域的新型常染色体隐性非综合征听力损伤基因座。  |  Santos, RL., et al. 2006. Hum Genet. 120: 85-92. PMID: 16703383
  6. 人类肺腺癌中的胆碱转运体:表达和功能影响。  |  Wang, T., et al. 2007. Acta Biochim Biophys Sin (Shanghai). 39: 668-74. PMID: 17805461
  7. 内耳中的 Cochlin 异构体及其与 CTL2(SLC44A2)的相互作用  |  Kommareddi, PK., et al. 2007. J Assoc Res Otolaryngol. 8: 435-46. PMID: 17926100
  8. 自身免疫性听力损失中重组人CTL2的自身抗体。  |  Kommareddi, PK., et al. 2009. Laryngoscope. 119: 924-32. PMID: 19319905
  9. CTL2/SLC44A2的同种型、表达、糖基化和组织分布。  |  Kommareddi, PK., et al. 2010. Protein J. 29: 417-26. PMID: 20665236
  10. 小鼠内耳中CTL2/SLC44A2及其同种型表达的年龄相关变化。  |  Beyer, LA., et al. 2011. Hear Res. 282: 63-8. PMID: 21986210
  11. CTL2转录变体在人类外周血细胞和人体组织中的表达。  |  Flesch, BK., et al. 2013. Transfusion. 53: 3217-23. PMID: 23480595
  12. 通过多重数字液滴PCR进行胎儿Ss、Kidd和CTL2血型预测的无创产前检测。  |  Wang, Y., et al. 2023. Ther Adv Hematol. 14: 20406207231179334. PMID: 37575175

订购信息

产品名称产品编号规格价格数量收藏夹

CTL2 抗体 (F7)

sc-101266
100 µg/ml
$333.00

CTL2 (F7): m-IgG Fc BP-HRP 套装

sc-539745
100 µg Ab; 10 µg BP
$354.00

CTL2 (F7): m-IgG1 BP-HRP 套装

sc-541681
100 µg Ab; 20 µg BP
$354.00

ist der Antikörper von Maus, der nicht nur Human-CTL-2 aber Maus-CTL-2 erkennt? Gibt es bereits eine Studie, ob dieser Antikörper auch funktionell was macht?

Asked by: sasen1
Thank you for your question. CTL2 Antibody (F7): sc-101266 is recommended for detection of CTL2 of mouse, rat and human origin by IP, IF, IHC(P) and ELISA. We do not have data on the antibody's performance in functional assays as opposed to detection applications.
Answered by: Tech Support Europe
Date published: 2023-02-28

Can sc-101266: CTL2 (F7) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: TinTin
Thank you for your question. Yes, sc-101266: CTL2 (F7) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from Good for detection of CTL2 in Western BlotThis antibody works well in human cell lines NCI-H460, Jurkat, and K-562, in mouse cell line C2C12, and rat cell line L8. -SCBT QC
Date published: 2023-09-14
Rated 4 out of 5 by from Great immunoperoxidase membrane and cytoplasmicGreat immunoperoxidase membrane and cytoplasmic staining in formalin-fixed, paraffin-embedded human lymphoma tissue. -SCBT QC
Date published: 2013-02-11
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CTL2 抗体 (F7) is rated 4.5 out of 5 by 2.
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