Date published: 2025-9-9

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Cortactin 抗体 (A-4): sc-55578

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说明书
  • Cortactin抗体(A-4)是小鼠单克隆IgG1 κ, 在9篇文献中引用,规格为200 µg/ml
  • 免疫human物种的Cortactin的氨基酸309-499
  • 抗-Cortactin 抗体 (A-4) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 Cortactin
  • 抗Cortactin抗体(A-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Cortactin (A-4): sc-55578免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 Cortactin 抗体 (A-4) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Cortactin 抗体 (A-4) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

Cortactin 抗体(A-4)是一种小鼠单克隆 IgG1 kappa 轻链抗体,专门用于识别 Cortactin(又称 Ems-1),Cortactin 是一种重要的丝状肌动蛋白(F-actin)结合蛋白,在细胞骨架调控中发挥着关键作用,影响着细胞的基本过程,如运动和形状维持。抗 Cortactin 抗体 (A-4) 是针对人 Cortactin 的 309-499 氨基酸制备的,具有很强的物种反应性,可在多种应用中有效检测小鼠、大鼠和人来源的 Cortactin,包括免疫印迹 (WB)、免疫沉淀 (IP)、免疫荧光 (IF)、石蜡包埋切片免疫组织化学 (IHCP) 和酶联免疫吸附试验 (ELISA)。Cortactin 是 Src p60 激酶的底物,它被 Src p60 激酶的酪氨酸磷酸化会改变其与 F-肌动蛋白的结合亲和力及其交联肌动蛋白丝的能力,从而影响细胞结构的完整性和动态性。从结构上看,Cortactin 的 N 端有 37 个氨基酸的串联重复序列,C 端有一个 SH3 结构域,这对其与肌动蛋白丝和各种信号分子的相互作用至关重要。此外,Cortactin 在 FGF-1 等生长因子的作用下会发生磷酸化,这表明它参与了信号转导途径。Cortactin 在巨核细胞和血小板中大量表达,表明它在这些细胞的成熟和功能中起着重要作用。Cortactin (A-4) 抗体有多种共轭形式,包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和各种 Alexa Fluor® 共轭物,为研究人员提供了多种选择,以满足不同的实验需求。抗 Cortactin 抗体 (A-4) 是科学家研究细胞骨架动力学、细胞信号转导机制和造血过程不可或缺的工具,可确保在研究中准确可靠地检测 Cortactin。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

Cortactin 抗体 (A-4)

sc-55578
200 µg/ml
$316.00

Cortactin (A-4): m-IgG Fc BP-HRP 套装

sc-526867
200 µg Ab; 10 µg BP
$354.00

Cortactin (A-4): m-IgG1 BP-HRP 套装

sc-532240
200 µg Ab; 20 µg BP
$354.00

Cortactin 抗体 (A-4) AC

sc-55578 AC
500 µg/ml, 25% agarose
$416.00

Cortactin 抗体 (A-4) HRP

sc-55578 HRP
200 µg/ml
$316.00

Cortactin 抗体 (A-4) FITC

sc-55578 FITC
200 µg/ml
$330.00

Cortactin 抗体 (A-4) PE

sc-55578 PE
200 µg/ml
$343.00

Cortactin 抗体 (A-4) Alexa Fluor® 488

sc-55578 AF488
200 µg/ml
$357.00

Cortactin 抗体 (A-4) Alexa Fluor® 546

sc-55578 AF546
200 µg/ml
$357.00

Cortactin 抗体 (A-4) Alexa Fluor® 594

sc-55578 AF594
200 µg/ml
$357.00

Cortactin 抗体 (A-4) Alexa Fluor® 647

sc-55578 AF647
200 µg/ml
$357.00

Cortactin 抗体 (A-4) Alexa Fluor® 680

sc-55578 AF680
200 µg/ml
$357.00

Cortactin 抗体 (A-4) Alexa Fluor® 790

sc-55578 AF790
200 µg/ml
$357.00

I need to use an antibody to detect the protein in samples of porcine origin. Do you know if this mouse monoclonal antibody will work?

Asked by: jerojero
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity
Answered by: Technical Support 15
Date published: 2017-02-13
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Rated 1 out of 5 by from Didn't work with rat primary cellsI bought this AB last week. It did not work with rat primary cells at all!!!!
Date published: 2018-05-29
Rated 5 out of 5 by from Specific signalA great antibody that will accurately detect your cortactin antibody. It works well for WB and staining in mouse, rat, and human samples. It has been published multiple times.
Date published: 2017-01-27
Rated 4 out of 5 by from Nice band seen in WB using HeLa whole cell lysateNice band seen in WB using HeLa whole cell lysate. -SCBT QC
Date published: 2015-06-06
Rated 4 out of 5 by from Publishable data in CoIP using human MalignantPublishable data in CoIP using human Malignant mesothelioma cells. -SCBT Publication Review
Date published: 2015-05-17
Rated 5 out of 5 by from Superb immunoperoxidase cytoplasmic stainingSuperb immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human adrenal gland tissue. -SCBT QC
Date published: 2015-05-05
Rated 4 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB -SCBT QC
Date published: 2015-01-24
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Cortactin 抗体 (A-4) is rated 3.8 out of 5 by 6.
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