Date published: 2026-1-31

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CD37 抗体 (HH1): sc-18881

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说明书
  • CD37抗体(HH1)是小鼠单克隆IgG1 κ, 在1篇文献中引用,规格为200 µg/ml
  • 针对滤泡性淋巴瘤患者的淋巴瘤细胞
  • CD37 抗体 (HH1) 推荐用于FCM,检测human 来源的 CD37
  • 抗CD37抗体(HH1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是CD37 Antibody (HH1). 的首选辅助检测试剂。这些试剂现与CD37 Antibody (HH1) 打包提供(请参阅下面的订购信息)。
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CD37抗体(HH1)是一种小鼠单克隆IgG1 kappa轻链抗体,可通过流式细胞术(FCM)检测人类CD37。抗CD37抗体(HH1)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。CD37是跨膜四跨家族(TSTF)的成员,该家族还包括其他细胞表面蛋白,如CD9、CD53、CD63、CD81和CD82,它们都具有四个疏水性的跨膜结构域。这些蛋白对于影响细胞发育、粘附、激活、生长和运动等信号转导事件至关重要。人类CD37基因位于19p13-q13.4染色体上,编码一种281个氨基酸的糖蛋白,通过与整合素和其他TSTF蛋白形成复合物,在T细胞和B细胞相互作用中发挥重要作用。CD37主要表达于正常和肿瘤性成熟sIg+ B细胞,而在静止和活化的T细胞、中性粒细胞、粒细胞和单核细胞上的表达较低。使用缺乏CD37的转基因小鼠模型进行的研究表明,淋巴器官的发育和细胞组成没有发生重大变化,这凸显了CD37在免疫系统调节中的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD37 抗体 (HH1) 参考文献:

  1. 在次优成本刺激条件下,靶向灭活四跨蛋白 CD37 会损害 T 细胞依赖性 B 细胞反应。  |  Knobeloch, KP., et al. 2000. Mol Cell Biol. 20: 5363-9. PMID: 10891477
  2. Dectin-1 与四跨蛋白 CD37 的相互作用可抑制 IL-6 的产生。  |  Meyer-Wentrup, F., et al. 2007. J Immunol. 178: 154-62. PMID: 17182550
  3. 用一种新型工程化小模块免疫药物靶向 CD37 阳性淋巴恶性肿瘤。  |  Zhao, X., et al. 2007. Blood. 110: 2569-77. PMID: 17440052
  4. 四跨蛋白 CD37 和 Tssc6 在细胞免疫中的互补作用。  |  Gartlan, KH., et al. 2010. J Immunol. 185: 3158-66. PMID: 20709950
  5. 人类白细胞抗原 CD37 的主要结构,它是大鼠 MRC OX-44 抗原的物种同源物。  |  Classon, BJ., et al. 1989. J Exp Med. 169: 1497-502. PMID: 2466944
  6. 四泛蛋白超家族:分子促进者。  |  Maecker, HT., et al. 1997. FASEB J. 11: 428-42. PMID: 9194523
  7. 正常和肿瘤性人类角朊细胞中四跨跨膜家族(CD9, CD37, CD53, CD63, CD81 和 CD82)的表达:CD9 与 alpha 3 beta 1 整合素的关联。  |  Okochi, H., et al. 1997. Br J Dermatol. 137: 856-63. PMID: 9470900

订购信息

产品名称产品编号规格价格数量收藏夹

CD37 抗体 (HH1)

sc-18881
200 µg/ml
$322.00

CD37 (HH1): m-IgG Fc BP-HRP 套装

sc-528338
200 µg Ab; 10 µg BP
$361.00

CD37 (HH1): m-IgGκ BP-HRP 套装

sc-520690
200 µg Ab, 40 µg BP
$361.00

CD37 (HH1): m-IgG1 BP-HRP 套装

sc-542876
200 µg Ab; 20 µg BP
$361.00

CD37 抗体 (HH1) AC

sc-18881 AC
500 µg/ml, 25% agarose
$424.00

CD37 抗体 (HH1) HRP

sc-18881 HRP
200 µg/ml
$322.00

CD37 抗体 (HH1) FITC

sc-18881 FITC
200 µg/ml
$336.00

CD37 抗体 (HH1) PE

sc-18881 PE
200 µg/ml
$349.00

CD37 抗体 (HH1) Alexa Fluor® 488

sc-18881 AF488
200 µg/ml
$364.00

CD37 抗体 (HH1) Alexa Fluor® 546

sc-18881 AF546
200 µg/ml
$364.00

CD37 抗体 (HH1) Alexa Fluor® 594

sc-18881 AF594
200 µg/ml
$364.00

CD37 抗体 (HH1) Alexa Fluor® 647

sc-18881 AF647
200 µg/ml
$364.00

CD37 抗体 (HH1) Alexa Fluor® 680

sc-18881 AF680
200 µg/ml
$364.00

CD37 抗体 (HH1) Alexa Fluor® 790

sc-18881 AF790
200 µg/ml
$364.00

Hi, I am wondering about the shelf life if the HH1 CD37 antibody? We use the APC conjugatedf or flow and can not seem to find info about shelf life. Best Regards, Gro

Asked by: CD37 HH1 APC shelf llife
Thank you for your question. CD37 (HH1) antibody is stable for one year from the date of purchase.
Answered by: BlakeJ
Date published: 2026-01-08

Can you share a picture of the HH1 HRP conjugate used in western blot please? What MW does it show the CD37? I understand there is some variation due to glycosylation, does it show multiple bands?

Asked by: mackie7
Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Support
Date published: 2021-07-22

Can CD37 (HH1): sc-18881 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: jenniferc
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, CD37 (HH1): sc-18881 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 3 out of 5 by from Produced satisfactory FCM data for BJAB cellsProduced satisfactory FCM data for BJAB cells. -SCBT QC
Date published: 2013-02-07
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CD37 抗体 (HH1) is rated 3.0 out of 5 by 1.
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