Date published: 2025-9-7

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CD24 抗体 (SN3): sc-19585

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说明书
  • CD24 抗体 SN3 是小鼠单克隆 IgG1 κ,CD24抗体, 在46篇文献中引用,规格为200 µg/ml
  • 针对NALM-1 human前B白血病细胞系的抗体
  • CD24 抗体 (SN3) 推荐用于 WB, IP, IF 和 FCM,检测mouse, rat 和human 来源的 CD24
  • 抗CD24抗体(SN3)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取CD24 (SN3): sc-19585免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgGκ BP-HRP是CD24 Antibody (SN3) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现可与CD24 Antibody (SN3) 搭配使用(请参阅下面的订购信息)。有关其它 m-IgGκ BP 结合物,请参阅我们完整的小鼠 IgG 结合蛋白列表。

快捷链接

関連項目

CD24抗体(SN3)是一种小鼠单克隆IgG1 kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和流式细胞术(FCM)检测小鼠、大鼠和人类来源的CD24蛋白。抗CD24抗体(SN3)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。CD24是一种以糖磷脂酰肌醇(GPI)为锚的膜唾液糖蛋白,主要表达于前B细胞、前B细胞和成熟B细胞,在B细胞激活后表达减少。CD24也存在于粒细胞和一小部分胸腺细胞和神经母细胞瘤中,但在浆细胞中不存在。CD24在调节B细胞增殖和分化中起着至关重要的作用,因此CD24在正常免疫反应和血液系统恶性肿瘤中都很重要。CD24表达与多种实体肿瘤有关,在边缘性卵巢浆液性肿瘤中,从顶端定位到细胞质染色的转变可作为基质侵袭的替代标记。作为分化标记,CD24在成熟的静止B细胞上表达,并在刺激后下调,这凸显了CD24在理解B细胞生物学和癌症潜在治疗靶点方面的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD24 抗体 (SN3) 参考文献:

  1. CD24 是人类乳腺癌的标志物。  |  Fogel, M., et al. 1999. Cancer Lett. 143: 87-94. PMID: 10465342
  2. CD24 通过糖脂富集膜域/移植物介导的信号系统诱导人 B 细胞凋亡。  |  Suzuki, T., et al. 2001. J Immunol. 166: 5567-77. PMID: 11313396
  3. CD24 在卵巢癌中表达,是影响患者生存的新的独立预后标志。  |  Kristiansen, G., et al. 2002. Am J Pathol. 161: 1215-21. PMID: 12368195
  4. 前 B 细胞抗原受体介导的信号可抑制 CD24 诱导的人类前 B 细胞凋亡。  |  Taguchi, T., et al. 2003. J Immunol. 170: 252-60. PMID: 12496407
  5. CD24 是一种在人类 B 细胞上表达的信号转导分子,也是小细胞肺癌的主要表面抗原。  |  Jackson, D., et al. 1992. Cancer Res. 52: 5264-70. PMID: 1327504
  6. 晚期卵巢浆液性边界肿瘤的细胞质 CD24 表达。  |  Choi, YL., et al. 2005. Gynecol Oncol. 97: 379-86. PMID: 15863133
  7. CD24 是一种调节 B 细胞活化反应的信号转导物,是一种具有糖基磷脂酰肌醇膜锚的极短肽。  |  Kay, R., et al. 1991. J Immunol. 147: 1412-6. PMID: 1831224
  8. 通过 CD24(磷脂肌醇锚定膜分子的新成员)在淋巴细胞和骨髓细胞中进行信号转导。  |  Fischer, GF., et al. 1990. J Immunol. 144: 638-41. PMID: 2153173
  9. 定义对特定造血细胞类型具有明显选择性的标记物的单克隆抗体也可检测神经嵴起源细胞上的抗原。  |  Kemshead, JT., et al. 1982. Hybridoma. 1: 109-23. PMID: 6208120
  10. B 淋巴细胞的表型表达。1.用单克隆抗体鉴定正常淋巴组织。  |  Hsu, SM. and Jaffe, ES. 1984. Am J Pathol. 114: 387-95. PMID: 6421166
  11. 小鼠 T 淋巴细胞上的热稳定抗原/CD24:成本刺激功能的证据。  |  Hubbe, M. and Altevogt, P. 1994. Eur J Immunol. 24: 731-7. PMID: 8125140
  12. 通过碳水化合物特异性 CD24 抗体交叉反应鉴定新型树突状细胞表面抗原。  |  Williams, LA., et al. 1996. Immunology. 89: 120-5. PMID: 8911149

订购信息

产品名称产品编号规格价格数量收藏夹

CD24 抗体 (SN3)

sc-19585
200 µg/ml
$316.00

CD24 (SN3): m-IgGκ BP-HRP 套装

sc-520692
200 µg Ab, 40 µg BP
$354.00

CD24 抗体 (SN3) AC

sc-19585 AC
500 µg/ml, 25% agarose
$416.00

CD24 抗体 (SN3) HRP

sc-19585 HRP
200 µg/ml
$316.00

CD24 抗体 (SN3) FITC

sc-19585 FITC
200 µg/ml
$330.00

CD24 抗体 (SN3) PE

sc-19585 PE
200 µg/ml
$343.00

CD24 抗体 (SN3) Alexa Fluor® 488

sc-19585 AF488
200 µg/ml
$357.00

CD24 抗体 (SN3) Alexa Fluor® 546

sc-19585 AF546
200 µg/ml
$357.00

CD24 抗体 (SN3) Alexa Fluor® 594

sc-19585 AF594
200 µg/ml
$357.00

CD24 抗体 (SN3) Alexa Fluor® 647

sc-19585 AF647
200 µg/ml
$357.00

CD24 抗体 (SN3) Alexa Fluor® 680

sc-19585 AF680
200 µg/ml
$357.00

CD24 抗体 (SN3) Alexa Fluor® 790

sc-19585 AF790
200 µg/ml
$357.00

Does sc-19585 work for IHC-FFPE human tissue?

Asked by: Dave12
Thank you for your question. Anti-CD24 Antibody (SN3) is only recommended for detection of CD24 of mouse, rat and human origin by WB, IP, IF and FCM. Based on our tests with this product, it is not suitable for IHC(P) applications.
Answered by: Tech Support Europe
Date published: 2022-10-18

Q about the SN3 (anti CD24) Ab specificity. Can you please provide information regarding the epitopte that this Ab recognizes? Are the epitops different from other commonly-used anti-CD mAbs such as M1/69?

Asked by: giltiayn
Thank you for your question. This mouse monoclonal CD24 antibody was raised against NALM-1 human pre-B leukemia cell line. The exact epitope recognized by this mouse monoclonal antibody has not yet been determined. Yes, this antibody has a unique epitope compared to other commercially available CD24 antibody clones.
Answered by: Technical Support
Date published: 2019-02-10

Why is CD24 Antibody (SN3): sc-19585 the recommended alternative to the now discontinued CD24 Antibody (FL-80): sc-11406?

Asked by: Trav11
Thank you for your question. The mouse monoclonal CD24 Antibody (SN3): sc-19585 offers a higher degree of specificity and eliminates lot-to-lot variation when compared to the polyclonal, sc-11406. It is also warrantied for all of the same applications as the discontinued polyclonal antibody: WB, IP, IF, and FCM. If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Technical Support 15
Date published: 2017-01-18
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Rated 4 out of 5 by from CD24 is suitable for flowI bought this antibody to perform flow analysis and I could detect it obviously
Date published: 2021-06-11
Rated 5 out of 5 by from Nice antibodyThank you very much for small aliquot sample. It was tested for flow cytometry, and demonstrated this antibody nicely works for that purpose.
Date published: 2021-05-14
Rated 5 out of 5 by from Great for Flow CitometryI received last month a free sample of this antibody. I used it for FACS and I obteined very good result! I recomend it.
Date published: 2017-10-12
Rated 5 out of 5 by from Very good and usefulI received this as a free sample.I use the antibody to detect the surface marker of nucleus pulposus cells. The results is satisfactory.
Date published: 2017-10-07
Rated 5 out of 5 by from CD24 surface immunofluorescence FACS-BestThis antibody can be used to detect surface CD24 to identify cancer stem cells with rapid tumorigenesis with other markers such as PD-L1 or VEGFR2. It works very well for surface immuno-FACS.
Date published: 2017-09-17
Rated 5 out of 5 by from Great WB and IF dataVery strong IF staining results; also clear, specific western !!
Date published: 2017-01-31
Rated 5 out of 5 by from Works Great!This antibody works great in western blot analysis of CD24 expression in non-transfected 293T: sc-117752, human CD24 transfected 293T: sc-116926 and human PBL (C) whole cell lysates.
Date published: 2016-12-22
Rated 3 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB -SCBT QC
Date published: 2015-06-18
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CD24 抗体 (SN3) is rated 4.3 out of 5 by 12.
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