CD16 Antibody (GRM1): sc-19594
- CD16 Antibody (GRM1) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
- raised against human prolymphocytic leukemia
- CD16 Antibody (GRM1) is recommended for detection of CD16 of human origin by WB, IP, IF, IHC(P) and FCM
- Anti-CD16 Antibody (GRM1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2a BP-HRP is the preferred secondary detection reagent for CD16 Antibody (GRM1) for WB and IHC(P) applications. This reagent is now offered in a bundle with CD16 Antibody (GRM1) (see ordering information below).
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CD16 Antibody (GRM1) is a mouse monoclonal IgG2a kappa light chain antibody, designed to detect human CD16, also known as Fc gamma receptor III (FcγRIII), across various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). CD16 is a crucial protein located on the surface of immune cells, where CD16 functions as a low-affinity receptor for the Fc region of IgG antibodies, facilitating antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis of targeted cells. CD16 exists in two primary isoforms: CD16A (FcγRIIIA), a transmembrane receptor expressed on natural killer (NK) cells and macrophages, and CD16B (FcγRIIIB), a glycosylphosphatidylinositol (GPI)-anchored protein found on neutrophils. The distinct localization of these isoforms is vital for their respective roles in the immune response, with CD16A requiring association with the γ subunit of FcεRI or the ζ subunit of the TCR-CD3 complex for proper cell surface expression. CD16 is uniquely present both as a transmembrane and GPI-anchored receptor, underscoring CD16′s versatile functions in immune regulation. CD16 monoclonal antibody (GRM1) is available in both non-conjugated form and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® variants, making CD16 monoclonal antibody (GRM1) adaptable for a wide range of experimental needs. Anti-CD16 antibody (GRM1) is essential for research into immune system dynamics, autoimmune diseases, and conditions such as paroxysmal nocturnal hemoglobinuria (PNH), where CD16 expression is significantly altered. With alternate names including FcγRIII, Fc gamma receptor III, CD16A, and CD16B, CD16 monoclonal antibody (GRM1) provides comprehensive detection capabilities for studying the diverse roles and mechanisms of CD16 within the immune milieu.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD16 Antibody (GRM1) | sc-19594 | 200 µg/ml | $322.00 | |||
CD16 Antibody (GRM1): m-IgG2a BP-HRP Bundle | sc-545914 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD16 Antibody (GRM1) AC | sc-19594 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CD16 Antibody (GRM1) HRP | sc-19594 HRP | 200 µg/ml | $322.00 | |||
CD16 Antibody (GRM1) FITC | sc-19594 FITC | 200 µg/ml | $336.00 | |||
CD16 Antibody (GRM1) PE | sc-19594 PE | 200 µg/ml | $349.00 | |||
CD16 Antibody (GRM1) Alexa Fluor® 488 | sc-19594 AF488 | 200 µg/ml | $364.00 | |||
CD16 Antibody (GRM1) Alexa Fluor® 546 | sc-19594 AF546 | 200 µg/ml | $364.00 | |||
CD16 Antibody (GRM1) Alexa Fluor® 594 | sc-19594 AF594 | 200 µg/ml | $364.00 | |||
CD16 Antibody (GRM1) Alexa Fluor® 647 | sc-19594 AF647 | 200 µg/ml | $364.00 | |||
CD16 Antibody (GRM1) Alexa Fluor® 680 | sc-19594 AF680 | 200 µg/ml | $364.00 | |||
CD16 Antibody (GRM1) Alexa Fluor® 790 | sc-19594 AF790 | 200 µg/ml | $364.00 |