Date published: 2026-10-16

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Uteroglobin/SCGB1A1/CC10 抗体 (B-6): sc-390313

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说明书
  • Uteroglobin/SCGB1A1/CC10抗体(B-6)是小鼠单克隆IgG2a κ, 在10篇文献中引用,规格为200 µg/ml
  • 免疫mouse物种的代表全长CC10的氨基酸1-96
  • 抗-Uteroglobin/SCGB1A1/CC10 抗体 (B-6) 推荐用于 WB, IP, IF 和 ELISA,检测mouse 和rat 来源的 CC10
  • 抗Uteroglobin/SCGB1A1/CC10抗体(B-6)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 2a BP-HRP">m-IgG2a BP-HRP是Uteroglobin/SCGB1A1/CC10 Antibody (B-6) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与Uteroglobin/SCGB1A1/CC10 Antibody (B-6) 打包提供(请参阅下面的订购信息)。
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Uteroglobin/SCGB1A1/CC10 抗体 (B-6) 是一种 IgG2a κ 小鼠单克隆 CC10 抗体,可通过 WB、IP、IF 和 ELISA 方法检测小鼠和大鼠来源的 CC10。Uteroglobin/SCGB1A1/CC10 抗体 (B-6) 既有非偶联的抗 CC10 抗体形式,也有多种偶联形式的抗 CC10 抗体,包括琼脂糖、HRP、PE、FITC 和多种 Alexa Fluor® 偶联物。Clara 细胞 10(CC10)蛋白是兔子宫球蛋白的同源物,是一种磷脂酶 A2 抑制剂。CC10 受 AP-1、八聚体和肝细胞核因子-3(HNF-3)家族转录因子的调控。CC10 的表达随卵巢月经周期而变化,人类子宫内膜中的表达可能受孕酮刺激,这表明 CC10 可能调节人类子宫中的类花生酸水平。CC10 在肺部的非纤毛气道上皮细胞和泌尿生殖道分泌物中表达。CC10 参与调节气道炎症,可能在哮喘中发挥作用。非小细胞肺癌细胞系 A549 中 CC10 的过度表达显示,MMP-2 和 MMP-9 基质金属蛋白酶几乎完全缺失,侵袭性降低,这表明 CC10 的缺失可能促进癌变。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Uteroglobin/SCGB1A1/CC10 抗体 (B-6) 参考文献:

  1. 小鼠和人类肺中 Clara 细胞中 CC10 的免疫定位。  |  Ryerse, JS., et al. 2001. Histochem Cell Biol. 115: 325-32. PMID: 11405061
  2. 顺式作用元件赋予肺上皮细胞CC10基因的表达。  |  Stripp, BR., et al. 1992. J Biol Chem. 267: 14703-12. PMID: 1634515
  3. 构建人CC10基因真核表达载体,并在肺腺癌A549细胞系中表达CC10蛋白。  |  Zhong, S., et al. 2005. J Huazhong Univ Sci Technolog Med Sci. 25: 505-7. PMID: 16463657
  4. 多剂量苯乙烯和 R-氧化苯乙烯对 CD-1 小鼠离体 Clara 细胞中 CC10, bax 和 bcl-2 表达的影响。  |  Harvilchuck, JA. and Carlson, GP. 2009. Toxicology. 259: 149-52. PMID: 19428955
  5. 大鼠大唾液腺克拉细胞分泌蛋白(CC10-CC26)和Annexin-1蛋白的免疫组织化学定位。  |  Cecchini, MP., et al. 2009. J Anat. 214: 752-8. PMID: 19438769
  6. 携带CC10的腺相关病毒2/9载体在OVA致敏小鼠中减轻肺部炎症反应。  |  Wu, CJ., et al. 2013. Hum Gene Ther. 24: 48-57. PMID: 23013277
  7. 来自 CC10+ 俱乐部队细胞的高移动组 box-1 蛋白可促进呼吸道合胞病毒感染后期的 2 型反应。  |  Chen, S., et al. 2019. Am J Physiol Lung Cell Mol Physiol. 316: L280-L290. PMID: 30407867
  8. 重组人CC10在预防早产儿慢性肺不张中的作用  |  Davis, JM., et al. 2019. Pediatr Res. 86: 254-260. PMID: 31086287
  9. 俱乐部细胞10-kDa蛋白(CC10)抑制cPLA2/COX2通路,减轻RSV引起的呼吸道炎症和AHR。  |  Yu, G., et al. 2020. Int Immunopharmacol. 83: 106327. PMID: 32172202
  10. 小鼠克拉细胞 10-kDa(CC10)蛋白:cDNA 核苷酸序列及不同物种 CC10 与孕酮结合力差异的分子基础  |  Singh, G., et al. 1993. Exp Lung Res. 19: 67-75. PMID: 8440203

订购信息

产品名称产品编号规格价格数量收藏夹

Uteroglobin/SCGB1A1/CC10 抗体 (B-6)

sc-390313
200 µg/ml
$322.00

Uteroglobin/SCGB1A1/CC10 (B-6): m-IgG2a BP-HRP 套装

sc-545960
200 µg Ab; 10 µg BP
$361.00

Uteroglobin/SCGB1A1/CC10 抗体 (B-6) AC

sc-390313 AC
500 µg/ml, 25% agarose
$424.00

Uteroglobin/SCGB1A1/CC10 抗体 (B-6) HRP

sc-390313 HRP
200 µg/ml
$322.00

Uteroglobin/SCGB1A1/CC10 抗体 (B-6) FITC

sc-390313 FITC
200 µg/ml
$336.00

Uteroglobin/SCGB1A1/CC10 抗体 (B-6) PE

sc-390313 PE
200 µg/ml
$349.00

Uteroglobin/SCGB1A1/CC10 抗体 (B-6) Alexa Fluor® 488

sc-390313 AF488
200 µg/ml
$364.00

Uteroglobin/SCGB1A1/CC10 抗体 (B-6) Alexa Fluor® 546

sc-390313 AF546
200 µg/ml
$364.00

Uteroglobin/SCGB1A1/CC10 抗体 (B-6) Alexa Fluor® 594

sc-390313 AF594
200 µg/ml
$364.00

Uteroglobin/SCGB1A1/CC10 抗体 (B-6) Alexa Fluor® 647

sc-390313 AF647
200 µg/ml
$364.00

Uteroglobin/SCGB1A1/CC10 抗体 (B-6) Alexa Fluor® 680

sc-390313 AF680
200 µg/ml
$364.00

Uteroglobin/SCGB1A1/CC10 抗体 (B-6) Alexa Fluor® 790

sc-390313 AF790
200 µg/ml
$364.00

Can CC10 (B-6): sc-390313 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Germaine
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, CC10 (B-6): sc-390313 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-03-01

I have a question related to applications of CC10 (B-6). There is a result by western blot in the datasheet. I wonder if CC10 (B-6) is applied to IHC-P using mouse tissue. Have you ever applied CC10 (B-6) to IHC-P? Let me know detailed information. Thanks

Asked by: Big Scientist
Thank you for your question. CC10 Antibody (B-6): sc-390313 has not yet been tested for IHC(P), or IHC on formalin-fixed paraffin-embedded tissue sections. We do offer an alternative antibody that has been tested for this application that we would recommend using instead, CC10 Antibody (E-11): sc-365992. https://www.scbt.com/scbt/product/cc10-antibody-e-11
Answered by: Technical Support
Date published: 2017-01-10
  • y_2026, m_10, d_16, h_11CST
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Rated 5 out of 5 by jaypea10 from Clear IF staining on mouse lung cellsCC10 (B-6) worked well at 1:400 dilution on mouse lung cell cytospins with Alexa fluor-647 secondary
Date published: 2018-01-23
Rated 5 out of 5 by Trav11 from Provides good WB dataThe CC10 Antibody (B-6): sc-390313 works well for Western blot applications, showing clear band with minimal background.
Date published: 2017-01-17
Rated 5 out of 5 by SS from Good results obtained by IHC using mouse tissueGood results obtained by IHC using mouse tissue.
Date published: 2015-07-13
Rated 5 out of 5 by TO from Produced positive Western blot data of CC10Produced positive Western blot data of CC10 expression in mouse lung tissue extract. -SCBT QC
Date published: 2013-04-28
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Uteroglobin/SCGB1A1/CC10 抗体 (B-6) is rated 5.0 out of 5 by 4.
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