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CB1/Cannabinoid Receptor 1/CNR1 Antibody (C-11) - Western Blotting - Image 389152 — CB1 抗体 (C-11): sc-518035. RAW 264. 7 (A), Neuro-2A (B), F9 (C) 和 c4 (D) 全细胞裂解液以及小鼠小脑组织提取物 (E) 中 CB1 表达的 Western 印迹分析.

CB1 抗体 (C-11): sc-518035. RAW 264. 7 (A), Neuro-2A (B), F9 (C) 和 c4 (D) 全细胞裂解液以及小鼠小脑组织提取物 (E) 中 CB1 表达的 Western 印迹分析.

CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11): sc-518035

Name: CB1/Cannabinoid Receptor 1/CNR1抗体 (C-11)
Brand: SCBT
SKU: sc-518035
Price: 316.0 USD
Availability: InStock

4.5(2)

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说明书

CB1/Cannabinoid Receptor 1/CNR1抗体(C-11)是小鼠单克隆IgG₁ κ, 在8篇文献中引用，规格为200 µg/ml
免疫human物种的的氨基酸1-150
抗-CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) 推荐用于 WB, IP, IF 和 ELISA，检测mouse, rat 和human 来源的 CB1
抗CB1/Cannabinoid Receptor 1/CNR1抗体（C-11）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
还可偶联Alexa Fluor^® 488, Alexa Fluor^® 546, Alexa Fluor^® 594 和 Alexa Fluor^® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
还可偶联Alexa Fluor^® 680 和 Alexa Fluor^® 790，用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR^®/Odyssey^®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
关于如何获取CB1/Cannabinoid Receptor 1/CNR1 (C-11): sc-518035的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
m-IgG Fc BP-HRP和 1 BP-HRP">m-IgG₁ BP-HRP是CB1/Cannabinoid Receptor 1/CNR1 Antibody (C-11) for WB applications. 的首选辅助检测试剂，这些试剂现与CB1/Cannabinoid Receptor 1/CNR1 Antibody (C-11) 打包提供（请参阅下面的订购信息）。

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関連項目

CB1抗体（C-11）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过应用诸如蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）和酶联免疫吸附测定（ELISA）等方法检测小鼠、大鼠和人类样本中的CB1。抗CB1抗体（C-11）有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物。CB1是G蛋白偶联受体家族的一员，通过抑制腺苷酸环化酶活性在调节精神活性大麻素的作用方面发挥着关键作用，而腺苷酸环化酶活性对于调节神经递质的释放和神经元的兴奋性至关重要。CB1主要在大脑中表达，在睾丸中的水平较低，这凸显了CB1在中枢神经系统功能（如疼痛感知、运动控制、记忆和神经内分泌调节）中的重要性。值得注意的是，CB1在丝氨酸316处的磷酸化已被证明会破坏CB1对钙通道的抑制作用，同时激活钾离子电流，表明存在一种复杂的调节机制，可能影响大脑的各种功能，并可能导致与大麻中的四氢大麻酚（THC）等物质相关的成瘾行为。CB1 (C-11) 抗体能够有效检测和鉴定 CB1，因此对于研究大麻素信号通路及其在生理和病理条件下的影响的研究人员来说，CB1 (C-11) 抗体是一种宝贵的工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor^® 是Molecular Probes Inc., OR., USA的商标

LI-COR^®和 Odyssey^® 是LI-COR Biosciences的注册商标

订购信息

产品名称	产品编号	规格	价格	数量	收藏夹
CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11)	sc-518035	200 µg/ml	$316.00
CB1/Cannabinoid Receptor 1/CNR1 (C-11): m-IgG Fc BP-HRP 套装	sc-528082	200 µg Ab; 10 µg BP	$354.00
CB1/Cannabinoid Receptor 1/CNR1 (C-11): m-IgG₁ BP-HRP 套装	sc-533455	200 µg Ab; 20 µg BP	$354.00
CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) AC	sc-518035 AC	500 µg/ml, 25% agarose	$416.00
CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) HRP	sc-518035 HRP	200 µg/ml	$316.00
CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) FITC	sc-518035 FITC	200 µg/ml	$330.00
CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) PE	sc-518035 PE	200 µg/ml	$343.00
CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) Alexa Fluor^® 488	sc-518035 AF488	200 µg/ml	$357.00
CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) Alexa Fluor^® 546	sc-518035 AF546	200 µg/ml	$357.00
CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) Alexa Fluor^® 594	sc-518035 AF594	200 µg/ml	$357.00
CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) Alexa Fluor^® 647	sc-518035 AF647	200 µg/ml	$357.00
CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) Alexa Fluor^® 680	sc-518035 AF680	200 µg/ml	$357.00
CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) Alexa Fluor^® 790	sc-518035 AF790	200 µg/ml	$357.00

2. since the Ab was from mouse, how could we avoid cross reaction by secondary Ab when the sample was mouse? should we using Fab or serum (source as secondary Ab) to block sample before incubating with 2nd Ab？wanting some useful guiding protocols.

Asked by: Lab410

感谢您的提问。如果您能直接拨打(+86) 021-60936350，或者发邮件到我们亚洲服务部的邮箱asia@scbio.cn我们就这个问题和其他相关问题进行更多的互动讨论，那将会很有帮助。 Thank you for your question.It would be helpful if you could call us directly at (+86) 021-60936350 or email our Asia Service department at asia@scbio.cn for more interactive discussions on this and other related issues.

Answered by: Zhanglong

Date published: 2023-11-09

1. the immunogen of the antibody was from N-terminal (1-150) of CB1, so when we tried to dual-stain using this Ab with other Abs in IF assay, we failed to co-localize multple receptor proteins. why not consider changing immunogen from N to C?

Asked by: Lab410

Answered by: Zhanglong

Date published: 2023-11-09

I am doing Western Blot (antibody was diluted1:500) and there are very sharp bands on ~38 kDa, some weak bands are also visible on ~65 kDa, but even when the exposure time is 35 minutes those 65 kDa bands are weak. Should I take the 38 kDa bands as CB1R?

Asked by: Yasaman

Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.

Answered by: Technical Support

Date published: 2023-11-08

Rated 4 out of 5 by Manu9 from Buon funzionamento in WBBanda chiara in WB con diluizione 1:500. Buon funzionamento.

Date published: 2024-05-03

Rated 5 out of 5 by SCBT QC Lab from Specific antibody for human and mouse CB1Antibody works well with human cell lines HeLa and THP-1 and mouse cerebellum. MW weight markers: Cruz Marker Molecular Weight Standards: sc-2035 -SCBT QC

Date published: 2023-09-14

CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) is rated 4.5 out of 5 by 2.

Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打0086-021-60936350联系我们。
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种属	基因名称	基因ID	染色体位置	亚型（mRNA）登录号	蛋白质登录号	OMIM™ 号码
Human	CNR1	Entrez Gene ID: 1268	6q15	XM_006715330, XM_011535424, XM_011535425, XM_011535426, XM_011535428, XM_017010238, XM_017010239, XM_017010240, NM_001160226, NM_001160258, NM_001160259, NM_016083, NM_033181, NM_001160260	UniProt ID: P21554	114610
Mouse	Cnr1	Entrez Gene ID: 12801	4 A5	XM_006537591, XM_006537592, XM_006537593, XM_006537594, XM_006537595, XM_017319939, NM_007726	UniProt ID: P47746	N/A

CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11): sc-518035

CB1/Cannabinoid Receptor 1/CNR1 抗体 (C-11) 规格

替代产品名称: CB1

产品克隆名称: C-11

分类: 一抗

Clonality: 单克隆抗体

抗体同型: IgG₁ kappa light chain

氨基酸: 1-150

抗原表位靶标: CB1

抗原表位种属: human

产品反应性/检测: CB1

种属反应性/检测: mouse, rat, human

其它哺乳动物反应性: N/A

其它非哺乳动物反应性: N/A

应用: WB, IP, IF, ELISA

瓶的信息: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

研究引文: 8篇各种科学出版物的引文

優選的 CB1/Cannabinoid Receptor 1/CNR1 抗體是 CB1/Cannabinoid Receptor 1/CNR1 抗體 (2F9): sc-293419.