Date published: 2025-9-10

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cathepsin E 抗体 (E-8): sc-166343

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说明书
  • cathepsin E抗体(E-8)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为200 µg/ml
  • 针对氨基酸141-180的图谱,在cathepsin E的内部区域,human起源
  • 推荐用于 mouse, rat 和 human 来源的cathepsin E WB, IP, IF, IHC(P) 和 ELISA检测
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 cathepsin E 抗体 (E-8) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与cathepsin E 抗体 (E-8) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

蛋白水解酶的组织蛋白酶家族包含几种不同的蛋白酶类。半胱氨酸蛋白酶类包括组织蛋白酶B、L、H、K、S和O。天冬氨酸蛋白酶类由组织蛋白酶D和E组成。Cath-epsin G属于丝氨酸蛋白酶类。大多数组织蛋白酶都是溶酶体的,每一种都参与细胞代谢,参与肽生物合成和蛋白质降解等各种事件。组织蛋白酶E是一种非溶酶体、细胞内的蛋白酶。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

cathepsin E 抗体 (E-8) 参考文献:

  1. 新型荧光底物的特性,用于快速、灵敏地检测组织蛋白酶E和D。  |  Yasuda, Y., et al. 1999. J Biochem. 125: 1137-43. PMID: 10348917
  2. 组织蛋白酶E在肥大细胞羧肽酶A处理中的作用。  |  Henningsson, F., et al. 2005. J Cell Sci. 118: 2035-42. PMID: 15860733
  3. 蛋白酶E缺乏导致一种新型溶酶体贮积病,表现为溶酶体膜唾液酸蛋白的积累和巨噬细胞中溶酶体pH值的升高。  |  Yanagawa, M., et al. 2007. J Biol Chem. 282: 1851-62. PMID: 17095504
  4. C57BL/6J小鼠免疫系统中的天然蛋白酶E缺乏。  |  Tulone, C., et al. 2007. Immunogenetics. 59: 927-35. PMID: 18000662
  5. 前蛋白酶E的自催化加工为蛋白酶E及其结构差异。  |  Athauda, SB., et al. 1991. Biochem Biophys Res Commun. 175: 152-8. PMID: 1998500
  6. 选择性检测组织蛋白酶E的蛋白水解活性。  |  Abd-Elgaliel, WR. and Tung, CH. 2010. Biochim Biophys Acta. 1800: 1002-8. PMID: 20600629
  7. 生酮饮食抑制了鼠脑中由钾酸诱导的Cathepsin E表达。  |  Jeong, HJ., et al. 2010. Yonsei Med J. 51: 653-60. PMID: 20635438
  8. Cathepsin E、maspin、Plk1和survivin是预测非肌肉浸润性膀胱癌进展的很有前景的蛋白标记物。  |  Fristrup, N., et al. 2012. Am J Pathol. 180: 1824-34. PMID: 22449953
  9. 临床前家族性淀粉样多发性神经病模型中骨髓来源巨噬细胞中下调的Cathepsin E表达。  |  Moreira, J., et al. 2019. Amyloid. 26: 63-64. PMID: 31343320
  10. 大鼠脾脏中组织蛋白酶D和组织蛋白酶E样酶的免疫化学差异。  |  Yamamoto, K., et al. 1980. J Biochem. 87: 511-6. PMID: 6766930

订购信息

产品名称产品编号规格价格数量收藏夹

cathepsin E 抗体 (E-8)

sc-166343
200 µg/ml
$316.00

cathepsin E (E-8): m-IgG Fc BP-HRP 套装

sc-540084
200 µg Ab; 10 µg BP
$354.00

cathepsin E (E-8): m-IgG1 BP-HRP 套装

sc-541894
200 µg Ab; 20 µg BP
$354.00

Can cathepsin E (E-8): sc-166343 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Germaine
Thank you for your question. Yes, cathepsin E (E-8): sc-166343 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from Produced excellent immunoperoxidase cytoplasmicProduced excellent immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human gall bladder tissue. -SCBT QC
Date published: 2015-04-10
Rated 5 out of 5 by from Great WB data obtained using human cathepsinGreat WB data obtained using human cathepsin E transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-01-19
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cathepsin E 抗体 (E-8) is rated 5.0 out of 5 by 2.
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