Date published: 2026-5-25

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CA I Antibody (F-11): sc-393497

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Datasheets
  • CA I Antibody (F-11) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 46-63 near the N-terminus of CA I of human origin
  • recommended for detection of CA I of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and canine and porcine
  • m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CA I Antibody (F-11) for WB and IHC(P) applications. These reagents are now offered in bundles with CA I Antibody (F-11) (see ordering information below).
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    CA I Antibody (F-11) is a mouse monoclonal IgG2b antibody that detects carbonic anhydrase I (CA I) in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). CA I plays a crucial role in the reversible hydration of carbon dioxide, which is essential for maintaining acid-base balance in the body, facilitating respiration, and supporting various physiological processes such as bone resorption and the formation of bodily fluids like saliva and gastric acid. Anti-CA I antibody (F-11) targets proteins primarily located in the cytoplasm, where CA I contributes to the regulation of pH and carbon dioxide levels, thereby influencing metabolic processes and cellular functions. Notably, while a severe deficiency of CA I does not lead to significant hematological or renal issues, CA I presence is vital for optimal physiological function, highlighting the importance of this enzyme in maintaining homeostasis. CA I (F-11) antibody serves as an invaluable tool for researchers studying the diverse roles of carbonic anhydrases in health and disease, providing insights into their function and potential therapeutic targets.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    CA I Antibody (F-11)

    sc-393497
    200 µg/ml
    $322.00

    CA I Antibody (F-11): m-IgGκ BP-HRP Bundle

    sc-535802
    200 µg Ab; 40 µg BP
    $361.00

    CA I Antibody (F-11): m-IgG2b BP-HRP Bundle

    sc-549478
    200 µg Ab; 10 µg BP
    $361.00

    CA I (F-11) Neutralizing Peptide

    sc-393497 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-393497 P appropriate for?

    Asked by: Trav11
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-27
    • y_2026, m_5, d_24, h_14CST
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    Rated 5 out of 5 by from Produced positive Western Blot data of CAProduced positive Western Blot data of CA I expression in HEL 92.1.7 and TF-1 whole cell lysates. -SCBT QC
    Date published: 2015-01-05
    Rated 5 out of 5 by from Great Western Blot data of CA I expression in nonGreat Western Blot data of CA I expression in non-transfected 293T and human CA I transfected 293T whole cell lysates and human spleen tissue extract . -SCBT QC
    Date published: 2014-04-15
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    CA I Antibody (F-11) is rated 5.0 out of 5 by 2.
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