BTEB2 Antibody (A-5): sc-398014
- BTEB2 Antibody (A-5) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 338-369 near the C-terminus of BTEB2 of human origin
- recommended for detection of BTEB2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and porcine
- TransCruz reagent for ChIP application (sc-398014 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for BTEB2 Antibody (A-5) for WB applications. These reagents are now offered in bundles with BTEB2 Antibody (A-5) (see ordering information below).
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BTEB2 Antibody (A-5) is a mouse monoclonal IgG2a antibody that detects BTEB2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BTEB2, a member of the C2H2 zinc finger family, plays a crucial role in gene regulation by binding to GC-rich motifs found in gene promoters, which can lead to either the activation or repression of transcriptional activities. BTEB2 is particularly important in vascular biology, as BTEB2 is expressed in the fetal aorta and is involved in the phenotypic modulation of vascular smooth muscle cells in response to mitogen stimulation, primarily through interaction with the early growth response protein 1 (Egr-1). Notably, BTEB2 is activated by mitogen-activated protein kinase pathways and is induced in the neointima following vascular injury, highlighting BTEB2′s significance in vascular remodeling and response to injury. BTEB2 (A-5) antibody is an essential tool for researchers studying the molecular mechanisms of vascular diseases and transcriptional regulation.
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BTEB2 Antibody (A-5) References:
- Binding of factor VIIa to tissue factor on keratinocytes induces gene expression. | Camerer, E., et al. 2000. J Biol Chem. 275: 6580-5. PMID: 10692465
- Positive- and negative-acting Kruppel-like transcription factors bind a transforming growth factor beta control element required for expression of the smooth muscle cell differentiation marker SM22alpha in vivo. | Adam, PJ., et al. 2000. J Biol Chem. 275: 37798-806. PMID: 10954723
- Inducible expression of BTEB2, a member of the zinc-finger family of transcription factors, in cardiac allograft arteriosclerosis. | Ogata, T., et al. 2000. Transplant Proc. 32: 2032-3. PMID: 11120052
- Regulation of human monoamine oxidase B gene by Sp1 and Sp3. | Wong, WK., et al. 2001. Mol Pharmacol. 59: 852-9. PMID: 11259630
- Helicobacter pylori infection induced alteration of gene expression in human gastric cells. | Chiou, CC., et al. 2001. Gut. 48: 598-604. PMID: 11302954
- Immunophenotypical characterization of contractile cells in caput epididymidis of men affected by congenital or post-inflammatory obstructive azoospermia. | Pelliccione, F., et al. 2005. Mol Hum Reprod. 11: 289-94. PMID: 15734898
- Krüppel-like factor 5 activates MEK/ERK signaling via EGFR in primary squamous epithelial cells. | Yang, Y., et al. 2007. FASEB J. 21: 543-50. PMID: 17158781
- Krüppel-like zinc-finger transcription factor 5 (KLF5) is highly expressed in large and giant unruptured cerebral aneurysms. | Nakajima, N., et al. 2012. World Neurosurg. 78: 114-21. PMID: 22120375
- cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2. | Sogawa, K., et al. 1993. Nucleic Acids Res. 21: 1527-32. PMID: 8479902
- Transcriptional regulation by the Sp family proteins. | Lania, L., et al. 1997. Int J Biochem Cell Biol. 29: 1313-23. PMID: 9570130
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BTEB2 Antibody (A-5) | sc-398014 | 200 µg/ml | $322.00 | |||
BTEB2 Antibody (A-5): m-IgG Fc BP-HRP Bundle | sc-538354 | 200 µg Ab; 10 µg BP | $361.00 | |||
BTEB2 Antibody (A-5): m-IgGκ BP-HRP Bundle | sc-535947 | 200 µg Ab; 40 µg BP | $361.00 | |||
BTEB2 Antibody (A-5): m-IgG2a BP-HRP Bundle | sc-548278 | 200 µg Ab; 10 µg BP | $361.00 | |||
BTEB2 (A-5) Neutralizing Peptide | sc-398014 P | 100 µg/0.5 ml | $69.00 | |||
BTEB2 Antibody (A-5) X | sc-398014 X | 200 µg/0.1 ml | $322.00 |