Date published: 2025-9-6

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beta Tubulin 抗体 (G-8): sc-55529

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说明书
  • beta Tubulin抗体(G-8)是小鼠单克隆IgG3 κ, 在108篇文献中引用,规格为200 µg/ml
  • 免疫human物种的β Tubulin的氨基酸210-444
  • 推荐用于 mouse, rat, human 和 来源的β Tubulin WB, IP, IF, IHC(P) 和 ELISA检测; 也和以下物种反应,包括: 和 equine, canine, bovine, porcine and avian
  • 看 beta Tubulin (D-10): sc-5274,可查看有标记的 beta Tubulin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 关于如何获取beta Tubulin (G-8): sc-55529免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG3 BP-HRPm-IgGκ BP-HRP是beta Tubulin Antibody (G-8) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂,这些试剂现与beta Tubulin Antibody (G-8) 打包提供(请参阅下面的订购信息)。

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関連項目

β Tubulin 抗体(G-8)是一种小鼠单克隆 IgG3 kappa 轻链抗体,设计用于靶向人 β Tubulin 的 210-444 氨基酸。β微管蛋白又称β1微管蛋白和β2微管蛋白(取决于其异构体),是通过与α微管蛋白异源二聚体形成微管所必需的。β Tubulin 主要位于细胞质中,在维持细胞形状、促进细胞内运输和使细胞正常分裂方面发挥着关键作用,所有这些对于正常的细胞功能和生物体发育都至关重要。β微管蛋白在细胞内的精确定位突显了它在有丝分裂、囊泡运输和细胞运动等动态过程中的重要性。抗β微管蛋白抗体(G-8)具有广泛的物种反应性,可有效识别小鼠、大鼠、人、禽、马、犬、牛和猪样本中的β微管蛋白,建议用于免疫印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、石蜡包埋切片免疫组织化学(IHCP)和酶联免疫吸附试验(ELISA)。包括神经元特异性 β3 管球蛋白在内的多种 β 管球蛋白异构体的存在突显了其在不同组织中的不同功能作用,而 β 管球蛋白(G-8)抗体则有助于研究这些异构体在生理和病理环境中的作用。β Tubulin(G-8)单克隆抗体在多种检测形式中表现稳定,是研究细胞骨架动力学、细胞分裂机制和相关疾病过程的研究人员不可或缺的工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

beta Tubulin 抗体 (G-8) 参考文献:

  1. 多西他赛耐药乳腺癌细胞中β-微管蛋白异型的改变  |  Shalli, K., et al. 2005. FASEB J. 19: 1299-301. PMID: 15946994
  2. β-微管蛋白mRNA降解共翻译调控的物理证据。  |  Theodorakis, NG. and Cleveland, DW. 1992. Mol Cell Biol. 12: 791-9. PMID: 1732744
  3. 人类原发性卵巢癌中 beta-tubulin异型蛋白的表达。  |  Ohishi, Y., et al. 2007. Gynecol Oncol. 105: 586-92. PMID: 17343904
  4. III类β-微管蛋白的表达与体外对微管靶向药物的耐药性。  |  Stengel, C., et al. 2010. Br J Cancer. 102: 316-24. PMID: 20029418
  5. 人类黑色素细胞系中的新型生物标志物--III类β-微管蛋白  |  Locher, H., et al. 2013. Differentiation. 85: 173-81. PMID: 23817083
  6. 管蛋白在酿酒酵母中过量表达的显性效应  |  Burke, D., et al. 1989. Mol Cell Biol. 9: 1049-59. PMID: 2657385
  7. 基于结构的方法设计作为微管蛋白聚合抑制剂的苯并咪唑-2-氨基甲酸酯衍生物。  |  Aguayo-Ortiz, R., et al. 2017. Chem Biol Drug Des. 90: 40-51. PMID: 28004475
  8. 尼日利亚塔拉巴州伊维菌素处理过的社区盘尾丝虫种群中β-微管蛋白同工型-1基因的单核苷酸多态性相关性  |  Akafyi, DE., et al. 2022. Acta Parasitol. 67: 267-274. PMID: 34279775
  9. 吡多胺和氨基胍可减轻β-微管蛋白的异常聚集以及甘油醛衍生的毒性高级糖化终产物对神经元生长的抑制。  |  Ooi, H., et al. 2022. Front Pharmacol. 13: 921611. PMID: 35721214
  10. 探究驱动蛋白与微管的相互作用  |  Tucker, C. and Goldstein, LS. 1997. J Biol Chem. 272: 9481-8. PMID: 9083088

订购信息

产品名称产品编号规格价格数量收藏夹

beta Tubulin 抗体 (G-8)

sc-55529
200 µg/ml
$316.00

beta Tubulin (G-8): m-IgGκ BP-HRP 套装

sc-521010
200 µg Ab, 40 µg BP
$354.00

beta Tubulin (G-8): m-IgG3 BP-HRP 套装

sc-552048
200 µg Ab; 40 µg BP
$354.00

How can beta-Tubulin Antibody (G-8): sc-55529 be used for double or triple staining, if the other primary antibodies are also raised in mouse?

Asked by: TinTin
In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. Please contact our Special Orders department for availability of directly conjugated beta-Tubulin (G-8), or see beta-Tubulin (D-10): sc-5274 for antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488 and Alexa Fluor® 647.
Answered by: Technical Service 11
Date published: 2017-01-09
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Rated 5 out of 5 by from GreatOutstanding loading control for western blot. We got defined and easy to measure bands.
Date published: 2022-07-28
Rated 2 out of 5 by from not excellentI used the antibody at a 1: 100 dilution, but the results were not excellent.
Date published: 2021-04-29
Rated 5 out of 5 by from Great Ab against TubulinI always use this Tubulin antibody for my Wb. It works great and signal is strong! I recommend it!
Date published: 2017-12-06
Rated 5 out of 5 by from Strong signalI used this antibody for Western blot at 1:100 in 5% milk. It gave me a strong specific signal at 55kDa.
Date published: 2017-10-09
Rated 5 out of 5 by from great antibody for western blotused at 1/1000 for western, give good signal, highly recommend it
Date published: 2017-08-29
Rated 5 out of 5 by from Excellent beta Tubulin detectionGreat antibody to detect beta-Tubulin. It is well published and works with mouse, rat, and human samples.
Date published: 2017-01-13
Rated 5 out of 5 by from Great monoclonal antibodyGreat monoclonal antibody, strong specific bands in A-431, BJAB, NIH/3T3 and KNRK whole cell lysates. -SCBT QC
Date published: 2015-03-05
Rated 4 out of 5 by from Good for WesternGood for Western, works in HeLa and BJAB. -SCBT QC
Date published: 2015-02-12
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beta Tubulin 抗体 (G-8) is rated 4.6 out of 5 by 9.
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