Date published: 2025-9-5

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Annexin V 抗体 (H-3): sc-74438

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说明书
  • Annexin V 抗体 H-3 是小鼠单克隆 IgG2a κ,Annexin V抗体, 在33篇文献中引用,规格为200 µg/ml
  • 与氨基酸1-319结合,代表全长Annexin V,human起源
  • Annexin V 抗体 (H-3) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 Annexin V
  • 抗Annexin V抗体(H-3)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Annexin V (H-3): sc-74438免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRP是Annexin V Antibody (H-3) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Annexin V Antibody (H-3) 打包提供(请参阅下面的订购信息)。

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関連項目

Annexin V抗体(H-3)是一种小鼠单克隆IgG2a kappa轻链抗体,用于检测Annexin V(也称为Lipocortin V或Annexin 5),可用于多种平台,包括蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)。Annexin V 单克隆抗体(H-3)针对的是全长人类 Annexin V 的氨基酸 1-319,对小鼠、大鼠和人类来源的 Annexin V 均表现出强烈的反应性。Annexin V是钙结合蛋白家族中一个重要的成员,主要定位于细胞膜,通过钙依赖性方式与磷脂酰丝氨酸结合,在调节细胞膜动态和细胞凋亡识别中发挥重要作用。这种定位对于细胞凋亡、炎症和细胞粘附等过程至关重要,使Annexin V成为细胞死亡和疾病机制研究中的重要标记物。Annexin V 单克隆抗体(H-3)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种 Alexa Fluor® 结合物,为各种实验应用提供了多种选择。抗Annexin V抗体(H-3)有助于对Annexin V的生物学功能及其在病理状态中的参与进行深入研究。Annexin V单克隆抗体(H-3)使研究人员能够有效地研究Annexin V的空间和时间表达模式,从而更深入地了解其在细胞中的关键作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Annexin V 抗体 (H-3) 参考文献:

  1. 多基因风险改变单基因肾脏疾病的易感性。  |  Assadi, M., et al. 2011. Med Hypotheses. 77: 43-6. PMID: 21440374
  2. 附件素 V 对间质细胞裂解物中蛋白激酶 C 活性的抑制作用。  |  Rothhut, B., et al. 1995. Eur J Biochem. 232: 865-72. PMID: 7588728
  3. Annexin IV 可抑制钙调蛋白依赖性蛋白激酶 II 激活的氯离子传导。离子通道调控的新机制。  |  Chan, HC., et al. 1994. J Biol Chem. 269: 32464-8. PMID: 7798247
  4. 人类 Annexin VIII 的不同组织表达。  |  Reutelingsperger, CP., et al. 1994. FEBS Lett. 349: 120-4. PMID: 8045287
  5. 急性早幼粒细胞白血病中附件素 VIII 基因的表达。  |  Liu, JH., et al. 1994. Leuk Lymphoma. 13: 381-6. PMID: 8069182
  6. 附件蛋白超级基因家族的结构演变。  |  Smith, PD. and Moss, SE. 1994. Trends Genet. 10: 241-6. PMID: 8091504
  7. S100C 与附件蛋白 I N 端结构域的钙依赖性结合。  |  Mailliard, WS., et al. 1996. J Biol Chem. 271: 719-25. PMID: 8557678
  8. 离子通道人附件素 V 中电压传感器的结构和功能特征。  |  Liemann, S., et al. 1996. J Mol Biol. 258: 555-61. PMID: 8636991
  9. 人类附件蛋白 III 的高分辨率晶体结构显示出与附件蛋白 V 的细微差别。  |  Favier-Perron, B., et al. 1996. Biochemistry. 35: 1740-4. PMID: 8639653
  10. 胶原蛋白(COL4A)突变是成人局灶性节段性肾小球硬化症最常见的突变。  |  Rodriguez-Garcia, MI., et al. 1996. Genomics. 31: 151-7. PMID: 8824796
  11. 精确肾脏病学中的内质网应激和单基因肾脏疾病。  |  van Engeland, M., et al. 1998. Cytometry. 31: 1-9. PMID: 9450519
  12. 健康和疾病中的Claudin-11:对髓鞘疾病、听力和生育能力的影响。  |  Rodriguez-Garcia, MI., et al. 1999. Biochem J. 337 (Pt 1): 125-31. PMID: 9854034

订购信息

产品名称产品编号规格价格数量收藏夹

Annexin V 抗体 (H-3)

sc-74438
200 µg/ml
$316.00

Annexin V (H-3): m-IgG Fc BP-HRP 套装

sc-525709
200 µg Ab; 10 µg BP
$354.00

Annexin V (H-3): m-IgG2a BP-HRP 套装

sc-546371
200 µg Ab; 10 µg BP
$354.00

Annexin V 抗体 (H-3) AC

sc-74438 AC
500 µg/ml, 25% agarose
$416.00

Annexin V 抗体 (H-3) HRP

sc-74438 HRP
200 µg/ml
$316.00

Annexin V 抗体 (H-3) FITC

sc-74438 FITC
200 µg/ml
$330.00

Annexin V 抗体 (H-3) PE

sc-74438 PE
200 µg/ml
$343.00

Annexin V 抗体 (H-3) Alexa Fluor® 488

sc-74438 AF488
200 µg/ml
$357.00

Annexin V 抗体 (H-3) Alexa Fluor® 546

sc-74438 AF546
200 µg/ml
$357.00

Annexin V 抗体 (H-3) Alexa Fluor® 594

sc-74438 AF594
200 µg/ml
$357.00

Annexin V 抗体 (H-3) Alexa Fluor® 647

sc-74438 AF647
200 µg/ml
$357.00

Annexin V 抗体 (H-3) Alexa Fluor® 680

sc-74438 AF680
200 µg/ml
$357.00

Annexin V 抗体 (H-3) Alexa Fluor® 790

sc-74438 AF790
200 µg/ml
$357.00

What is the liklihood this Annexin V antibody would work with FFPE dog liver?

Asked by: Nancy
Thank you for your question. We have not validated the antibody for dog. There is a 56% homology in dog and we only recommend if the homology is 95% or higher .
Answered by: BlakeJ
Date published: 2024-03-21

I would like to try FREE 10 µg sample of Annexin V (H-3): sc-74438. How do I go about requesting it.

Asked by: Shyam Gajavelli
Thank you for your question. Please contact our Technical support group by phone at 800-457-3801 ext 2, or via live chat directly on our website, www.scbt.com, and we would be happy to assist you with a sample for sc-74438, Annexin V (H-3) .
Answered by: Tech Service
Date published: 2018-01-18

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: jerojero
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 15
Date published: 2017-01-20
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Rated 4 out of 5 by from Good Annexin V Antibiby for WBObtained good and clean WB results with Annexin V Antibody
Date published: 2021-12-15
Rated 5 out of 5 by from Good Annexin V antibody for WBVery good and clean WB results with Annexin V antibody.
Date published: 2017-10-18
Rated 5 out of 5 by from Wow !! Superb dataOutstanding product for WB,IF and IHC staining applications
Date published: 2017-02-05
Rated 5 out of 5 by from Looking for a Annexin V antibody for WB?This antibody is a really smart choice if you are looking for a solid Annexin V antibody for WB. It's reliable and gives nice strong bands.
Date published: 2016-12-30
Rated 4 out of 5 by from Good antibody for western blot analysisGood antibody for western blot analysis. It can be used up to 1:1000 for the detection of exosomes and microvesicles purified from cell culture medium and human serum.
Date published: 2015-11-25
Rated 5 out of 5 by from Publishable data obtained by WB using ratPublishable data obtained by WB using rat and human samples: PC6-3, HEK293 cells. -SCBT Publication Review
Date published: 2015-05-17
Rated 5 out of 5 by from Literature supports the use of this antibodyLiterature supports the use of this antibody for use in WB using human extracellular vesicles. -SCBT Publication Review
Date published: 2015-04-21
Rated 5 out of 5 by from Good specificity shown by using transfectedGood specificity shown by using transfected and non-transfected 293T cells for over-expression of the Annexin V protein via Western Blot analysis. Endogenous levels also detected by antibody. -SCBT QC
Date published: 2015-04-14
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Annexin V 抗体 (H-3) is rated 4.8 out of 5 by 12.
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