Date published: 2025-9-6

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ANG I 抗体 (C-1): sc-74528

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说明书
  • ANG I 抗体 C-1 是小鼠单克隆 IgG2a κ,ANG I抗体, 在23篇文献中引用,规格为200 µg/ml
  • 免疫human物种的ANG I的氨基酸25-147
  • ANG I 抗体 (C-1) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 precursor and mature ANG I
  • 抗ANG I抗体(C-1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取ANG I (C-1): sc-74528免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是ANG I Antibody (C-1) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与ANG I Antibody (C-1) 打包提供(请参阅下面的订购信息)。

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関連項目

ANG I抗体(C-1)是一种IgG2a κ小鼠单克隆ANG I抗体(也称为ANGI抗体、RNASE5抗体、血管生成素核糖核酸酶RNase A家族5抗体、核糖核酸酶A家族成员5抗体、核糖核酸酶5抗体、RNase 5抗体、RAA1抗体、核糖核酸酶A A1抗体、RNASE4抗体或ALS9抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人类来源的ANG I蛋白。ANG I抗体(C-1)既有非偶联型抗ANG I抗体形式,也有多种偶联型抗ANG I抗体形式,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。血管生成被定义为从已建立的微循环中形成新生血管和新血管的过程。血管生成素(ANG或ANG I)是一种非糖基化多肽,长度为123个氨基酸,其功能是该过程的核心。ANG I与已知的核糖核酸酶(如胰核糖核酸酶A)具有高度同源性,并且ANG I诱导血管生长的能力严重依赖于其核糖核酸酶活性。ANG I被认为参与实体瘤的发展,ANG I拮抗剂能够抑制肿瘤生长。通过一种尚不清楚的机制,ANG I被亚汇合内皮细胞内吞并转移到细胞核,在核仁中积累。ANG I受体尚未被确定。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

ANG I 抗体 (C-1) 参考文献:

  1. 将人类血管生成素基因定位在染色体 14q11 带,靠近 T 细胞受体 alpha/delta 基因座。  |  Weremowicz, S., et al. 1990. Am J Hum Genet. 47: 973-81. PMID: 1978563
  2. 血管生成素介导的 tsRNA 通过调节 NLRP3 炎症小体控制炎症和代谢紊乱。  |  Cai, J., et al. 2024. Cell Death Differ. 31: 1057-1069. PMID: 38740959
  3. 血管生成:最新进展。  |  Díaz-Flores, L., et al. 1994. Histol Histopathol. 9: 807-43. PMID: 7534514
  4. 血管生成:模型和调节剂。  |  Cockerill, GW., et al. 1995. Int Rev Cytol. 159: 113-60. PMID: 7537724
  5. 分辨率为 1.5-A 的牛血管生成素晶体结构。  |  Acharya, KR., et al. 1995. Proc Natl Acad Sci U S A. 92: 2949-53. PMID: 7708754
  6. 血管生成素颉颃物能阻止体内肿瘤生长。  |  Olson, KA., et al. 1995. Proc Natl Acad Sci U S A. 92: 442-6. PMID: 7831307
  7. 牛血管生成素的质子共振分配和二级结构。  |  Reisdorf, C., et al. 1994. Eur J Biochem. 224: 811-22. PMID: 7925406
  8. 鉴定人类血管生成素的细胞核靶向信号。  |  Moroianu, J. and Riordan, JF. 1994. Biochem Biophys Res Commun. 203: 1765-72. PMID: 7945327
  9. 血管生成素通过刺激细胞相关的蛋白水解活性,促进培养的内皮细胞的侵袭性。  |  Hu, G., et al. 1994. Proc Natl Acad Sci U S A. 91: 12096-100. PMID: 7991590
  10. 血管生成素单链免疫融合:融合蛋白结构域之间的肽链和间隔的影响。  |  Newton, DL., et al. 1996. Biochemistry. 35: 545-53. PMID: 8555226
  11. 人类血管生成素催化中心亚位点的动力学和建模综合研究。  |  Russo, N., et al. 1996. Proc Natl Acad Sci U S A. 93: 804-8. PMID: 8570639

订购信息

产品名称产品编号规格价格数量收藏夹

ANG I 抗体 (C-1)

sc-74528
200 µg/ml
$316.00

ANG I (C-1): m-IgG Fc BP-HRP 套装

sc-528684
200 µg Ab; 10 µg BP
$354.00

ANG I (C-1): m-IgGκ BP-HRP 套装

sc-521133
200 µg Ab, 40 µg BP
$354.00

ANG I (C-1): m-IgG2a BP-HRP 套装

sc-547146
200 µg Ab; 10 µg BP
$354.00

ANG I 抗体 (C-1) AC

sc-74528 AC
500 µg/ml, 25% agarose
$416.00

ANG I 抗体 (C-1) HRP

sc-74528 HRP
200 µg/ml
$316.00

ANG I 抗体 (C-1) FITC

sc-74528 FITC
200 µg/ml
$330.00

ANG I 抗体 (C-1) PE

sc-74528 PE
200 µg/ml
$343.00

ANG I 抗体 (C-1) Alexa Fluor® 488

sc-74528 AF488
200 µg/ml
$357.00

ANG I 抗体 (C-1) Alexa Fluor® 546

sc-74528 AF546
200 µg/ml
$357.00

ANG I 抗体 (C-1) Alexa Fluor® 594

sc-74528 AF594
200 µg/ml
$357.00

ANG I 抗体 (C-1) Alexa Fluor® 647

sc-74528 AF647
200 µg/ml
$357.00

ANG I 抗体 (C-1) Alexa Fluor® 680

sc-74528 AF680
200 µg/ml
$357.00

ANG I 抗体 (C-1) Alexa Fluor® 790

sc-74528 AF790
200 µg/ml
$357.00

sc-74528: Does this antibody work for IHC on human tissue?

Asked by: Guanghong
Thank you for your question. ANG I Antibody (C-1): sc-74528 is recommended for detection of human frozen tissue sections by IHC.
Answered by: Technical Service SH
Date published: 2025-08-12

What is the best condition to use this antibody for ANG IP in A549 cells? Thanks!

Asked by: Xiaoyong
Thank you for your question. We do not have any data using this antibody in A549 cells. Please refer to our website for the most up to date information availalbe for this antibody. Please contact our Technical Service Department if you would like further support.
Answered by: Technical Support
Date published: 2019-08-17

Can ANG I (C-1): sc-74528 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Randy McDonald
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, ANG I (C-1): sc-74528 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from ANG IWorks perfect in Western Blot. Used in 5% milk powder.
Date published: 2017-10-10
Rated 5 out of 5 by from Geeignet für Western BlotAn humanen Fibroblasten ausgestestet, funktioniert sehr gut.
Date published: 2017-09-26
Rated 5 out of 5 by from 抗体的特异性很好,试验进行的很顺利I buy ANG1 antibody was 2 month ago,and this antibody was very useful
Date published: 2017-09-12
Rated 5 out of 5 by from Funktioniert sehr gut im Western BlotIch habe eine Probe von SCBT getestet und bin mit dem Ergebnis im WB sehr zufrieden.
Date published: 2017-09-07
Rated 5 out of 5 by from suitable for WBThis antibody suitable for ANG I analysis,the antibody is outstanding quality for WB analyisis.Very clear band seen at 17kda, no background.
Date published: 2017-08-26
Rated 5 out of 5 by from performs very wellThis antibody performs very well and show high reproducibility for different samples, with excellent experimental results at 1:500,got strong signal.
Date published: 2017-07-22
Rated 4 out of 5 by from works good in IHCit works good on western blot using human skin tissue
Date published: 2017-07-05
Rated 5 out of 5 by from signal is wonderfuI use ANG I at a dilution 1:500 in western blot , 4℃ over night , signal is wonderful.
Date published: 2017-06-01
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ANG I抗体 (C-1) is rated 4.9 out of 5 by 11.
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