Date published: 2025-9-7

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AKAP 10 抗体 (E-7): sc-166192

5.0(2)
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说明书
  • AKAP 10抗体(E-7)是小鼠单克隆IgG2a (kappa轻链),规格为200 µg/ml
  • 针对氨基酸508-662的抗原,在AKAP 10的C-terminus处映射,human来源
  • 推荐用于 human 来源的AKAP 10 WB, IP, IF 和 ELISA检测
  • 2a BP-HRP">m-IgG2a BP-HRP是AKAP 10 Antibody (E-7) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与AKAP 10 Antibody (E-7) 打包提供(请参阅下面的订购信息)。

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    関連項目

    II型环磷酸腺苷-蛋白激酶(PKA)是一种具有广泛底物的多功能激酶。PKA信号的特异性被认为是由激酶在细胞内的特定位点的分隔所介导的。为了维持这种特定的定位,PKA的调节(R)亚基(RI和RII)与特定的R锚定蛋白(称为AKAPs,A激酶锚定蛋白)相互作用。AKAP 10(A激酶锚定蛋白10),也称为PRKA10或D-AKAP2(双重特异性A激酶锚定蛋白2),是一种由662个氨基酸组成的线粒体膜蛋白,属于AKAP家族。AKAP 10是一种双重特异性蛋白,可与PKA的I型和II型调节亚基结合,并将它们锚定在质膜或线粒体上。当锚定在线粒体上时,PKA可以磷酸化,从而灭活促凋亡蛋白Bad。这表明AKAP 10通过介导PKA的线粒体附着间接调节Bad诱导的凋亡。此外,AKAP 10可能促进G蛋白偶联信号转导,并可能作为多蛋白复合物组装的适配器。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    AKAP 10 抗体 (E-7)

    sc-166192
    200 µg/ml
    $316.00

    AKAP 10 (E-7): m-IgG2a BP-HRP 套装

    sc-546028
    200 µg Ab; 10 µg BP
    $354.00

    I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with AKAP 10 (E-7): sc-166192?

    Asked by: jenniferc
    We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 5 out of 5 by from Great Western Blot data of AKAP 10 expressionGreat Western Blot data of AKAP 10 expression in Caki-1 whole cell lysate. -SCBT QC
    Date published: 2015-03-08
    Rated 5 out of 5 by from Produced positive Western Blot data of AKAPProduced positive Western Blot data of AKAP 10 expression in non-transfected and human AKAP 10 transfected 293T whole cell lysates. -SCBT QC
    Date published: 2013-08-13
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    AKAP 10 抗体 (E-7) is rated 5.0 out of 5 by 2.
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