AKAP 10 Antibody (E-7): sc-166192
- AKAP 10 Antibody (E-7) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 508-662 mapping at the C-terminus of AKAP 10 of human origin
- recommended for detection of AKAP 10 of human origin by WB, IP, IF and ELISA
- m-IgG2a BP-HRP is the preferred secondary detection reagent for AKAP 10 Antibody (E-7) for WB applications. This reagent is now offered in a bundle with AKAP 10 Antibody (E-7) (see ordering information below).
AKAP 10 Antibody (E-7) is a mouse monoclonal IgG2a antibody that detects AKAP 10 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). AKAP 10, also known as PRKA10 or D-AKAP2, is a 662 amino acid protein located in the mitochondrial membrane, playing a crucial role in the spatial regulation of protein kinase A (PKA) signaling. AKAP 10′s unique localization allows anchoring of both type I and II regulatory subunits of PKA to the mitochondria, facilitating the phosphorylation of pro-apoptotic proteins like Bad, thereby influencing apoptotic pathways. This anchoring mechanism not only helps in the modulation of apoptosis but also suggests AKAP 10′s involvement in G-protein coupled signal transduction and the assembly of multiprotein complexes, highlighting its importance in cellular signaling and survival. Anti-AKAP 10 antibody (E-7) serves as an essential tool for researchers studying the intricate roles of PKA in various cellular processes and its implications in diseases related to apoptosis and signal transduction.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AKAP 10 Antibody (E-7) | sc-166192 | 200 µg/ml | $322.00 | |||
AKAP 10 Antibody (E-7): m-IgG2a BP-HRP Bundle | sc-546028 | 200 µg Ab; 10 µg BP | $361.00 |