Ah Receptor Antibody (C-4): sc-74572

Ah Receptor Antibody (C-4) is a mouse monoclonal IgG2b antibody that detects Ah Receptor in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Ah Receptor, also known as aromatic hydrocarbon receptor (AhR), plays a crucial role in mediating biological responses to environmental toxins, particularly 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). AhR (C-4) antibody recognizes a protein that functions as a ligand-dependent transcription factor regulating gene expression involved in xenobiotic metabolism and cellular responses to environmental stressors. Upon binding to TCDD or other ligands, Ah Receptor translocates to the nucleus, forming a complex with Ah Receptor nuclear translocator (Arnt). This complex then binds to specific DNA sequences known as xenobiotic responsive elements (XREs), leading to transcriptional activation of target genes. Anti-AhR antibody (C-4) serves as an essential tool for studying mechanisms of action of TCDD and other environmental pollutants, as well as their impact on human health, given Ah Receptor′s vital role in maintaining cellular homeostasis and protecting against toxic insults.

The preferred Ah Receptor antibody is Ah Receptor Antibody (A-3): sc-133088.