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Adenosine A1-R Antibody (HA1) - Western Blotting - Image 138541
腺苷 A1-R 抗体 (HA1): sc-66193. 293T 全细胞裂解液 (A) 和小鼠脑组织提取物 (B) 中腺苷 A1-R 表达的 Western 印迹分析.
Adenosine A1-R Antibody (HA1) - Western Blotting - Image 138541
腺苷 A1-R 抗体 (HA1): sc-66193. 293T 全细胞裂解液 (A) 和小鼠脑组织提取物 (B) 中腺苷 A1-R 表达的 Western 印迹分析.
Adenosine A1-R Antibody (HA1) - Western Blotting - Image 372370
腺苷 A1-R 抗体 (HA1): sc-66193. K-562 (A), NIH/3T3 (B) 和 C6 (C) 全细胞裂解液中腺苷 A1-R 表达的 Western 印迹分析.
Adenosine A1-R Antibody (HA1) - Western Blotting - Image 372367
腺苷 A1-R 抗体 (HA1): sc-66193. 腺苷 A1-R 在 ACHN (A) 和 Caco-2 (B) 全细胞裂解液中的表达的 Western 印迹分析.
腺苷 A1-R 抗体 (HA1): sc-66193. 293T 全细胞裂解液 (A) 和小鼠脑组织提取物 (B) 中腺苷 A1-R 表达的 Western 印迹分析.

Adenosine A1-R 抗体 (HA1): sc-66193

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寫評論提問

说明书
  • Adenosine A1-R 抗体 HA1 是小鼠单克隆 IgM κ，Adenosine A1-R抗体, 在4篇文献中引用，规格为200 µg/ml
  • 针对合成腺苷6-氨基己酸
  • 推荐用于 mouse, rat 和 human 来源的Adenosine A1-R WB, IP 和 IF检测
  • 关于如何获取Adenosine A1-R (HA1): sc-66193的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前，我们还没有完成Adenosine A1-R 抗体 (HA1)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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研究信息

関連項目

此外 Adenosine A Receptor 抗体包括 Adenosine A1-R 和 Adenosine A2A-R

腺苷A1-R抗体（HA1）是一种IgM κ小鼠单克隆腺苷A1-R抗体（也称为腺苷A1受体抗体、腺苷受体A1抗体或RDC7抗体），可通过蛋白质印迹法（WB）、免疫沉淀法（IP）和免疫荧光法（IF）检测小鼠、大鼠和人类来源的腺苷A1-R蛋白。腺苷A1-R抗体（HA1）为非偶联形式的抗腺苷A1-R抗体。腺苷参与多种过程，包括尿素的合成、抗炎反应以及蛋白质合成的抑制。腺苷受体，包括腺苷A1-R、腺苷A2A-R、腺苷A2B-R和腺苷A3-R，是G蛋白偶联受体家族的成员，属于整体膜蛋白。腺苷A1-R以部分钙依赖的方式介导尿素生成。已知腺苷通过腺苷A2A-R介导冠状血管扩张。在某些细胞中，腺苷通过A2B受体抑制胶原蛋白合成和总蛋白合成。腺苷A3-R的激活可抑制TNFα的诱导，并阻断内毒素CD14受体的信号转导通路。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Adenosine A1-R 抗体 (HA1) 参考文献:

  1. 人脑腺苷 A2b 受体的分子克隆和表达。  |  Pierce, KD., et al. 1992. Biochem Biophys Res Commun. 187: 86-93. PMID: 1325798
  2. 人脑腺苷 A2 受体的分子特征。  |  Furlong, TJ., et al. 1992. Brain Res Mol Brain Res. 15: 62-6. PMID: 1331670
  3. 大鼠大脑 A1 腺苷受体的克隆和表达。  |  Mahan, LC., et al. 1991. Mol Pharmacol. 40: 1-7. PMID: 1857334
  4. 使用裂解萤光素酶检测法研究腺苷A1受体介导的β-arrestin 2募集。  |  Saecker, L., et al. 2023. Front Pharmacol. 14: 1172551. PMID: 37324481
  5. 腺苷通过腺苷A1受体刺激肾近端小管基底侧50 pS K+通道。  |  Liu, H., et al. 2023. Front Physiol. 14: 1242975. PMID: 37700760
  6. 激活肝腺苷A1受体可通过抑制SREBP的成熟来改善MASH。  |  Zhu, W., et al. 2024. Cell Rep Med. 5: 101477. PMID: 38508143
  7. 激活肝腺苷A1受体可通过抑制SREBP的成熟来改善MASH。  |  Zhu, W., et al. 2024. Cell Rep Med. 5: 101563. PMID: 38718795
  8. 人类 A3 腺苷受体的分子克隆和特征描述。  |  Salvatore, CA., et al. 1993. Proc Natl Acad Sci U S A. 90: 10365-9. PMID: 8234299
  9. 激活巨噬细胞上的腺苷 A3 受体可抑制肿瘤坏死因子-α。  |  McWhinney, CD., et al. 1996. Eur J Pharmacol. 310: 209-16. PMID: 8884219
  10. 腺苷通过 A2B 受体抑制人主动脉平滑肌细胞的生长  |  Dubey, RK., et al. 1998. Hypertension. 31: 516-21. PMID: 9453355
  11. A2A 腺苷受体介导冠状动脉血管扩张。  |  Belardinelli, L., et al. 1998. J Pharmacol Exp Ther. 284: 1066-73. PMID: 9495868
  12. 大鼠肝细胞中三种腺苷受体反应的 Ca2+ 依赖性。  |  Guinzberg, R., et al. 1997. Eur J Pharmacol. 340: 243-7. PMID: 9580059

订购信息

产品名称产品编号规格价格数量收藏夹

Adenosine A1-R 抗体 (HA1)

sc-66193
200 µg/ml
$316.00

Is this product available as a sample to test for compatibility in house?

Asked by: Pooh
Thank you for your question. Yes, a 10 µg sample size of this antibody is available. Contact our Technical Service Department for more information on how to receive a free 10 µg sample of Adenosine A1-R (HA1): sc-66193.
Answered by: Tech Support Europe
Date published: 2020-06-23

For Western Blot, is it recommended to use denatured or non-denatured conditions with Adenosine A1-R (HA1): sc-66193 monoclonal antibody?

Asked by: jenniferc
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-02-27
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Rated 1 out of 5 by from Not buyit didn't work with my HepG2 whole cell lysates of 20ug.
Date published: 2021-12-02
Rated 4 out of 5 by from Good productTested this antibody a month ago and worked just as well as the Millipore antibody. Overall happy with the results.
Date published: 2017-12-29
Rated 4 out of 5 by from Robust signal in WB in 293T whole cell lysateRobust signal in WB in 293T whole cell lysate and mouse brain tissue extract. -SCBT QC
Date published: 2014-01-22
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Adenosine A1-R 抗体 (HA1) is rated 3.0 out of 5 by 3.
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