Date published: 2026-6-3

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Twinkle Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Twinkle Antibodies for advanced research in mitochondrial biology. Twinkle Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Twinkle is a crucial mitochondrial helicase that plays a significant role in the replication and maintenance of mitochondrial DNA. Its proper function is essential for mitochondrial integrity and energy production, making it a key player in cellular metabolism and overall cellular health. Dysregulation of Twinkle has been implicated in various mitochondrial disorders, highlighting its importance in both basic and clinical research. Researchers worldwide rely on Twinkle monoclonal antibodies to investigate mitochondrial DNA maintenance and replication mechanisms. Understanding Twinkle's role in mitochondrial function has opened new avenues for studying metabolic diseases and potential therapeutic interventions. Investigating Twinkle expression patterns helps reveal crucial insights into mitochondrial disorders and their underlying mechanisms. Santa Cruz Biotechnology monoclonal antibodies for Twinkle support researchers in advancing our understanding of mitochondrial biology and its impact on human health.

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Twinkle Antibodies

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Twinkle Antibody (1C5)

sc-293368mouse IgG2a κ591-684 (h)WB, IP, ELISAh
1
(2)

Twinkle CRISPR Knockout, HDR and Double Nickase Plasmids

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Twinkle CRISPR/Cas9 KO Plasmid (h)

sc-404159hGene KnockoutGFP0
(0)

Twinkle CRISPR/Cas9 KO Plasmid (m)

sc-432601mGene KnockoutGFP0
(0)

Twinkle Double Nickase Plasmid (m)

sc-432601-NICmGene KnockoutPuromycin0
(0)

Twinkle CRISPR Activation Products

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Twinkle CRISPR Activation Plasmid (h)

sc-404159-ACThGene ActivationPuro, Blast, Hygro0
(0)

Twinkle siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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Twinkle siRNA (h)

sc-63177hGene SilencingN/A0
(0)

Twinkle shRNA Plasmid (h)

sc-63177-SHhGene SilencingPuromycin0
(0)

Twinkle shRNA (h) Lentiviral Particles

sc-63177-VhGene SilencingPuromycin0
(0)

Twinkle siRNA (m)

sc-63178mGene SilencingN/A0
(0)

Twinkle shRNA Plasmid (m)

sc-63178-SHmGene SilencingPuromycin0
(0)

Twinkle shRNA (m) Lentiviral Particles

sc-63178-VmGene SilencingPuromycin0
(0)