Date published: 2026-6-2

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TWIK-1 Antibodies

Santa Cruz Biotechnology delivers a wide array of TWIK-1 monoclonal antibodies for research focused on understanding TWIK-1's role in various physiological processes. Multiple applications are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). TWIK-1, or KCNK1, belongs to the two-pore domain potassium channel family and maintains resting membrane potential while regulating cellular excitability. TWIK-1 functions are essential in heart and nervous system tissues, contributing to neuronal signaling and cardiac rhythm regulation. Research has shown TWIK-1's significance in multiple cellular processes and its potential involvement in various pathophysiological conditions. Understanding TWIK-1 expression patterns and regulatory mechanisms provides valuable insights into neurological disorders and cardiac diseases. Investigating TWIK-1's molecular interactions and cellular distribution advances knowledge in membrane transport and ion channel biology. TWIK-1 monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance scientific understanding of cellular physiology and disease mechanisms.

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TWIK-1 Antibodies

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TWIK-1 Antibody (4D7)

sc-517040mouse IgG1 κ265-336 (h)WB, IP, ELISAm, r, h
2
(1)

TWIK-1 CRISPR Knockout, HDR and Double Nickase Plasmids

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TWIK-1 CRISPR/Cas9 KO Plasmid (h)

sc-405238hGene KnockoutGFP0
(0)

TWIK-1 HDR Plasmid (h)

sc-405238-HDRhHomology Directed RepairPuromycin0
(0)

TWIK-1 Double Nickase Plasmid (h)

sc-405238-NIChGene KnockoutPuromycin0
(0)

TWIK-1 Double Nickase Plasmid (h2)

sc-405238-NIC-2hGene KnockoutPuromycin0
(0)

TWIK-1 CRISPR/Cas9 KO Plasmid (m)

sc-421243mGene KnockoutGFP
1
(0)

TWIK-1 HDR Plasmid (m)

sc-421243-HDRmHomology Directed RepairPuromycin
1
(0)

TWIK-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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TWIK-1 siRNA (h)

sc-42349hGene SilencingN/A
1
(0)

TWIK-1 shRNA Plasmid (h)

sc-42349-SHhGene SilencingPuromycin
1
(0)

TWIK-1 shRNA (h) Lentiviral Particles

sc-42349-VhGene SilencingPuromycin
1
(0)

TWIK-1 siRNA (m)

sc-42350mGene SilencingN/A0
(0)

TWIK-1 shRNA Plasmid (m)

sc-42350-SHmGene SilencingPuromycin0
(0)

TWIK-1 shRNA (m) Lentiviral Particles

sc-42350-VmGene SilencingPuromycin0
(0)