PKA I alpha reg激活剂
Santa Cruz Biotechnology now offers a broad range of PKA I alpha reg Activators. Protein kinase A (PKA), also known as cAMP-dependent protein kinase (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism and gene transcription by activation of the cAMP-dependent protein kinase (cAPK or PKA). PKA I alpha reg Activators offered by Santa Cruz activate PKA I alpha reg and, in some cases, other cAMP-dependent protein kinase and proliferation related proteins. View detailed PKA I alpha reg Activator specifications, including PKA I alpha reg Activator CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
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| 产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
福斯可林直接刺激腺苷酸环化酶，从而增加cAMP的产生。cAMP水平升高可与PKA的调节亚基（如PKA Iα reg）结合，从而释放并激活催化亚基。 | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $41.00 | 4 | |
抑制环氧化酶（COX）酶，减少前列腺素的生成，从而减少炎症。 | ||||||
Ibuprofen | 15687-27-1 | sc-200534 sc-200534A | 1 g 5 g | $52.00 $86.00 | 6 | |
非选择性COX抑制剂，通过抑制参与前列腺素合成的COX酶来减轻炎症、疼痛和发烧。 | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX是一种非选择性磷酸二酯酶抑制剂。通过抑制分解cAMP的磷酸二酯酶，IBMX可提高细胞内cAMP水平，从而激活PKA Iα reg。 | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
这种化合物是cAMP的合成、细胞渗透性类似物。它可以直接与PKA的调节亚基（如PKA Iα reg）结合，促进相关催化亚基的激活。 | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
抑制二氢叶酸还原酶，破坏快速分裂细胞的DNA合成，常用于癌症和自身免疫性疾病。 | ||||||
Sp-cAMPS | 93602-66-5 | sc-201571 | 1 mg | $95.00 | 3 | |
与8-溴-cAMP类似，Sp-cAMPS是一种可渗透细胞膜的cAMP类似物，可直接与PKA Iα reg结合并激活该酶。 | ||||||
Allopurinol | 315-30-0 | sc-207272 | 25 g | $128.00 | ||
抑制黄嘌呤氧化酶，减少尿酸的产生，用于治疗痛风和高尿酸血症。 | ||||||
Calcium dibutyryladenosine cyclophosphate | 362-74-3 | sc-482205 | 25 mg | $147.00 | ||
db-cAMP是另一种可渗透细胞膜并直接激活PKA Iα reg的cAMP类似物。 | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $40.00 $102.00 $197.00 $1739.00 $16325.00 | ||
肾上腺素与细胞上的β-肾上腺素受体结合，通过G蛋白发出信号，激活腺苷酸环化酶。腺苷酸环化酶活性增强，可提高cAMP水平，进而激活PKA Iα reg。 | ||||||