GM2/GD2 Synthase Activators
GM2/GD2 Synthase Activators are chemical compounds that specifically influence signaling events leading to the direct or indirect activation of GM2/GD2 Synthase. These compounds work by targeting various cellular structures and pathways that GM2/GD2 Synthase is involved in. For instance, sialic acid and N-Acetylneuraminic Acid are substrates for GM2/GD2 Synthase, which adds sialic acid to gangliosides GM3 and GD3 to form GM2 and GD2, respectively. Increased availability of these substrates can logically enhance the functional activity of GM2/GD2 Synthase. Similarly, Uridine Diphosphate (UDP) acts as a co-substrate for GM2/GD2 Synthase. An increase in the availability of UDP can enhance the enzyme's functional activity. Glucosamine, a building block for glycosaminoglycans, can indirectly promote GM2/GD2 Synthase activity by contributing to the formation of gangliosides. Additionally, components of the ceramide backbone in gangliosides, such as sphingosine and ceramide, can boost the enzyme's activity by providing more substrate for the enzymatic reaction.
Gangliosides GM3 and GD3, which GM2/GD2 Synthase modifies to form GM2 and GD2 respectively, are also key in influencing the enzyme's activity. Increased substrate availability can directly lead to enhanced activation of GM2/GD2 Synthase. Other compounds, like Hyaluronic Acid and Chondroitin Sulfate, glycosaminoglycans associated with gangliosides, can indirectly enhance GM2/GD2 Synthase activity by increasing the availability of substrate for the enzyme. Lastly, galactose and N-Acetylgalactosamine, components of gangliosides, can boost the activity of GM2/GD2 Synthase by increasing the availability of these crucial components. These compounds, therefore, work collectively to enhance the functional activity of GM2/GD2 Synthase.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-Acetylneuraminic acid | 131-48-6 | sc-281055A sc-281055 sc-281055D sc-281055B sc-281055C | 1 g 5 g 25 g 100 g 250 g | $84.00 $156.00 $326.00 $572.00 $1363.00 | ||
Sialic acid is a substrate for GM2/GD2 Synthase, which adds sialic acid to gangliosides GM3 and GD3 to form GM2 and GD2, respectively. Increased availability of sialic acid can logically enhance the functional activity of GM2/GD2 Synthase. | ||||||
D-Glucosamine | 3416-24-8 | sc-278917A sc-278917 | 1 g 10 g | $201.00 $779.00 | ||
Glucosamine serves as a building block for glycosaminoglycans, which are part of gangliosides. Increased availability of glucosamine can logically lead to increased substrate for GM2/GD2 Synthase, thereby enhancing its functional activity. | ||||||
D-erythro-Sphingosine | 123-78-4 | sc-3546 sc-3546A sc-3546B sc-3546C sc-3546D sc-3546E | 10 mg 25 mg 100 mg 1 g 5 g 10 g | $90.00 $194.00 $510.00 $2448.00 $9384.00 $15300.00 | 2 | |
Sphingosine is a part of the ceramide backbone in gangliosides. An increase in the availability of sphingosine can logically lead to increased substrate for GM2/GD2 Synthase, thereby enhancing its functional activity. | ||||||
C-8 Ceramide | 74713-59-0 | sc-205233 sc-205233A sc-205233B | 1 mg 5 mg 25 mg | $19.00 $63.00 $228.00 | 1 | |
Ceramide is a component of gangliosides that GM2/GD2 Synthase modifies. An increase in the availability of ceramide can logically lead to enhanced functional activity of GM2/GD2 Synthase. | ||||||
Chondroitin Sulfate, Bovine | 9007-28-7 | sc-203888 | 5 g | $94.00 | 1 | |
Chondroitin sulfate is a glycosaminoglycan associated with gangliosides. Increased availability can logically lead to increased substrate for GM2/GD2 Synthase, thereby enhancing its functional activity. | ||||||
Ganglioside GM3 sodium salt | 54827-14-4 | sc-202628 sc-202628A sc-202628B | 1 mg 10 mg 50 mg | $321.00 $2295.00 $9384.00 | ||
Ganglioside GM3 is a substrate for GM2/GD2 Synthase, which adds a sialic acid to form GM2. Increased availability of GM3 can logically enhance the functional activity of GM2/GD2 Synthase. | ||||||
Hyaluronic acid | 9004-61-9 | sc-337865 | 10 mg | $208.00 | ||
Hyaluronic acid is a glycosaminoglycan associated with gangliosides. Increased availability can logically lead to increased substrate for GM2/GD2 Synthase, thereby enhancing its functional activity. | ||||||
D-Galactose | 59-23-4 | sc-202564 | 100 g | $288.00 | 4 | |
Galactose is a component of gangliosides, which are substrates for GM2/GD2 Synthase. Increased availability of galactose can logically enhance the functional activity of GM2/GD2 Synthase. | ||||||
N-Acetyl-D-galactosamine | 1811-31-0 | sc-221979 sc-221979A sc-221979C sc-221979B sc-221979D | 10 mg 100 mg 1 g 5 g 50 g | $51.00 $77.00 $267.00 $1040.00 $1326.00 | ||
N-Acetylgalactosamine is a component of gangliosides, which are substrates for GM2/GD2 Synthase. Increased availability of N-Acetylgalactosamine can logically enhance the functional activity of GM2/GD2 Synthase. | ||||||