Date published: 2025-9-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

Ethyl gallate (CAS 831-61-8)

0.0(0)
Write a reviewAsk a question

See product citations (1)

Alternate Names:
Ethyl 3,4,5-trihydroxybenzoate
Application:
Ethyl gallate is a compound produced from gallic acid and ethanol found in natural plant sources
CAS Number:
831-61-8
Purity:
≥99%
Molecular Weight:
198.17
Molecular Formula:
C9H10O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Ethyl gallate, also referred to as 2-ethoxybenzoic acid and ethyl 3,4,5-trihydroxybenzoate, is a naturally occurring phenolic compound present in various plants. It exists as a colorless solid without any odor and melts at a temperature range of 158-160° C. Laboratory studies have revealed its ability to scavenge reactive oxygen species and inhibit the production of cytokines. Additionally, ethyl gallate has demonstrated inhibitory effects on the growth of various fungal species, including Candida albicans, Aspergillus niger, and Trichophyton mentagrophytes.


Ethyl gallate (CAS 831-61-8) References

  1. Benefits of ethyl gallate versus norepinephrine in the treatment of cardiovascular collapse in Pseudomonas aeruginosa septic shock in dogs.  |  Gotes, J., et al. 2012. Crit Care Med. 40: 560-72. PMID: 22020237
  2. Ethyl gallate induces apoptosis of HL-60 cells by promoting the expression of caspases-8, -9, -3, apoptosis-inducing factor and endonuclease G.  |  Kim, WH., et al. 2012. Int J Mol Sci. 13: 11912-11922. PMID: 23109891
  3. Ethyl gallate attenuates acute lung injury through Nrf2 signaling.  |  Mehla, K., et al. 2013. Biochimie. 95: 2404-14. PMID: 24018486
  4. Ethyl gallate suppresses proliferation and invasion in human breast cancer cells via Akt-NF-κB signaling.  |  Cui, H., et al. 2015. Oncol Rep. 33: 1284-90. PMID: 25522911
  5. Ethyl Gallate Displays Elicitor Activities in Tobacco Plants.  |  Goupil, P., et al. 2017. J Agric Food Chem. 65: 9006-9012. PMID: 28960978
  6. Stimulation of the Production of Prostaglandin E₂ by Ethyl Gallate, a Natural Phenolic Compound Richly Contained in Longan.  |  Wang, HR., et al. 2018. Biomolecules. 8: PMID: 30200641
  7. Ethyl gallate as a novel ERK1/2 inhibitor suppresses patient-derived esophageal tumor growth.  |  Liu, F., et al. 2019. Mol Carcinog. 58: 533-543. PMID: 30499613
  8. Protective effects of ethyl gallate on H2O2-induced mitochondrial dysfunction in PC12 cells.  |  Chen, L., et al. 2019. Metab Brain Dis. 34: 545-555. PMID: 30746596
  9. Pentagalloyl Glucose- and Ethyl Gallate-Rich Extract from Maprang Seeds Induce Apoptosis in MCF-7 Breast Cancer Cells through Mitochondria-Mediated Pathway.  |  Kantapan, J., et al. 2020. Evid Based Complement Alternat Med. 2020: 5686029. PMID: 32382295
  10. Estrogenic activity of ethyl gallate and its potential use in hormone replacement therapy.  |  Lee, H., et al. 2021. Bioorg Med Chem Lett. 40: 127919. PMID: 33711444
  11. The benzoate plant metabolite ethyl gallate prevents cellular- and vascular-lipid accumulation in experimental models of atherosclerosis.  |  Liu, W., et al. 2021. Biochem Biophys Res Commun. 556: 65-71. PMID: 33839416
  12. Improving the Solubility, Dissolution, and Bioavailability of Metronidazole via Cocrystallization with Ethyl Gallate.  |  Li, J., et al. 2021. Pharmaceutics. 13: PMID: 33919704
  13. Protective Mechanism of Ethyl Gallate against Intestinal Ischemia-Reperfusion Injury in Mice by in Vivo and in Vitro Studies Based on Transcriptomics.  |  Fan, S., et al. 2023. Chem Biodivers. 20: e202200643. PMID: 36513607
  14. Ethyl Gallate Isolated from Castanopsis cuspidata var. sieboldii Branches Inhibits Melanogenesis and Promotes Autophagy in B16F10 Cells.  |  Choi, MH., et al. 2023. Antioxidants (Basel). 12: PMID: 36829827

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl gallate, 100 g

sc-239928
100 g
$96.00