Molecular structure of Xanthine, CAS Number: 69-89-6
Xanthine (CAS 69-89-6)
See product citations (13)
Alternate Names:
2,6-dioxopurine
Application:
Xanthine is an adenosine receptor antagonist
CAS Number:
69-89-6
Purity:
≥99%
Molecular Weight:
152.1
Molecular Formula:
C5H4N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Xanthine is a purine base, which is used in synthesis as an intermediate in the degradation of adenosine monophosphate to uric acid (sc-213135). It is known that Xanthine is found in most body tissues and fluids in various organisms. Biologically Xanthine is produced from guanine (sc-211573) by cypin (guanine deaminase) and it can be separated in the lab using amberlite resin. In addition, Xanthine act as constituents of nucleic acids. Furthermore, Xanthines act as antagonists for adenosine receptors, with selectivity depending on whether there are substitution of alkyl groups.
Xanthine (CAS 69-89-6) References
- The use of amberlite resin in a separation of xanthine and guanine. | SMITH, SC. and WENDER, SH. 1948. J Am Chem Soc. 70: 3719. PMID: 18102928
- Xanthine microsensor based on polypyrrole molecularly imprinted film modified carbon fiber microelectrodes. | Liu, B., et al. 2013. Anal Biochem. 440: 220-6. PMID: 23747534
- Inverting the G-Tetrad Polarity of a G-Quadruplex by Using Xanthine and 8-Oxoguanine. | Cheong, VV., et al. 2016. Angew Chem Int Ed Engl. 55: 160-3. PMID: 26563582
- Colorimetric determination of xanthine in urine based on peroxidase-like activity of WO3 nanosheets. | Li, Z., et al. 2019. Talanta. 204: 278-284. PMID: 31357294
- Insights into xanthine riboswitch structure and metal ion-mediated ligand recognition. | Xu, X., et al. 2021. Nucleic Acids Res. 49: 7139-7153. PMID: 34125892
- Structural organization of xanthine crystals in the median ocellus of a member of the ancestral insect group Archaeognatha. | Friedman, O., et al. 2022. J Struct Biol. 214: 107834. PMID: 35077832
- Adenosine receptors: development of selective agonists and antagonists. | Daly, JW., et al. 1987. Prog Clin Biol Res. 230: 41-63. PMID: 3588607
- Brushite nanoparticles based electrochemical sensor for detection of uric acid, xanthine, hypoxanthine and caffeine. | Sudhan, N., et al. 2022. Anal Biochem. 659: 114947. PMID: 36216144
- A sensing platform based on Cu-MOF encapsulated Dawson-type polyoxometalate crystal material for electrochemical detection of xanthine. | Zhang, L., et al. 2022. Mikrochim Acta. 190: 24. PMID: 36515741
- Simultaneous Determination of Xanthine and Hypoxanthine Using Polyglycine/rGO-Modified Glassy Carbon Electrode. | Wang, T., et al. 2023. Molecules. 28: PMID: 36771122
- Xanthine-derived reactive oxygen species exacerbates adipose tissue disorders in male db/db mice induced by real-ambient PM2.5 exposure. | Chen, L., et al. 2023. Sci Total Environ. 882: 163592. PMID: 37087002
- Xanthine-induced deficits in hippocampal behavior and abnormal expression of hemoglobin genes. | Kambe, J., et al. 2023. Behav Brain Res. 449: 114476. PMID: 37148916
- Xanthine interference with dipyridamole-thallium-201 myocardial imaging. | Stanek, EJ., et al. 1995. Ann Pharmacother. 29: 425-7. PMID: 7633022
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Xanthine, 5 g | sc-204403 | 5 g | $26.00 |