Date published: 2025-10-14

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trans-2-Decenoic Acid (CAS 334-49-6)

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Alternate Names:
trans-2-Decylenic Acid
Application:
trans-2-Decenoic Acid is a fatty acid identified in royal jelly honey bee secretions
CAS Number:
334-49-6
Purity:
≥95%
Molecular Weight:
170.25
Molecular Formula:
C10H18O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Trans-2-Decenoic Acid, with the CAS number 334-49-6, is a monounsaturated fatty acid characterized by a trans double bond between the second and third carbon atoms in its ten-carbon chain. This specific structural configuration grants the molecule distinctive physical and chemical properties compared to its cis counterparts and saturated fatty acids. In research, trans-2-Decenoic Acid has been extensively studied for its ability to influence the behavior of microbial communities, particularly in the formation and disruption of biofilms. Biofilms are complex layers of microorganisms that adhere to surfaces and are protected by a self-produced matrix. The trans configuration of the double bond in trans-2-Decenoic Acid is thought to interfere with the communication systems within microbial populations, such as quorum sensing, which are crucial for the maintenance and development of biofilms. This fatty acid has been used as a model compound to understand the mechanisms by which certain molecules can penetrate biofilms and disrupt microbial signaling, leading to potential applications in controlling biofilm-associated issues in various environments, including industrial and bioprocessing settings. Additionally, its role in modifying lipid membranes and influencing membrane fluidity and permeability has been a subject of study, providing insights into the fundamental interactions between fatty acids and cellular structures.


trans-2-Decenoic Acid (CAS 334-49-6) References

  1. Royal jelly and its unique fatty acid, 10-hydroxy-trans-2-decenoic acid, promote neurogenesis by neural stem/progenitor cells in vitro.  |  Hattori, N., et al. 2007. Biomed Res. 28: 261-6. PMID: 18000339
  2. Estrogenic activities of Fatty acids and a sterol isolated from royal jelly.  |  Suzuki, KM., et al. 2008. Evid Based Complement Alternat Med. 5: 295-302. PMID: 18830443
  3. Streptococcus mutans inhibits Candida albicans hyphal formation by the fatty acid signaling molecule trans-2-decenoic acid (SDSF).  |  Vílchez, R., et al. 2010. Chembiochem. 11: 1552-62. PMID: 20572249
  4. Disintegration of aerobic granules induced by trans-2-decenoic acid.  |  Cai, PJ., et al. 2013. Bioresour Technol. 128: 823-6. PMID: 23186667
  5. Alkenyl Carboxylic Acid: Engineering the Nanomorphology in Polymer-Polymer Solar Cells as Solvent Additive.  |  Zhang, Y., et al. 2017. ACS Appl Mater Interfaces. 9: 13396-13405. PMID: 28368094
  6. Cupriavidus sp. HN-2, a Novel Quorum Quenching Bacterial Isolate, is a Potent Biocontrol Agent Against Xanthomonas campestris pv. campestris.  |  Ye, T., et al. 2019. Microorganisms. 8: PMID: 31881662
  7. Efficient Biosynthesis of 10-Hydroxy-2-decenoic Acid Using a NAD(P)H Regeneration P450 System and Whole-Cell Catalytic Biosynthesis.  |  Wang, L., et al. 2022. ACS Omega. 7: 17774-17783. PMID: 35664602
  8. Titanium coated with 2-decenoic analogs reduces bacterial and fungal biofilms.  |  Harrison, ZL., et al. 2023. J Appl Microbiol. 134: PMID: 37481696
  9. Royal jelly: a predictive, preventive and personalised strategy for novel treatment options in non-communicable diseases.  |  Baptista, BG., et al. 2023. EPMA J. 14: 381-404. PMID: 37605655
  10. Biosynthesis of 10-Hydroxy-2-decenoic Acid through a One-Step Whole-Cell Catalysis.  |  Fang, K., et al. 2024. J Agric Food Chem. 72: 1190-1202. PMID: 38175798

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

trans-2-Decenoic Acid, 25 ml

sc-296572
25 ml
$203.00