Date published: 2025-10-14

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Sodium xylenesulfonate (CAS 1300-72-7)

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Alternate Names:
Dimethylbenzenesulfonic acid sodium salt; Xylenesulfonic acid sodium salt
CAS Number:
1300-72-7
Molecular Weight:
208.21
Molecular Formula:
C8H9NaO3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Sodium xylenesulfonate is a compound that has attention in various research sectors due to its surfactant properties, enhancing the solubility of less soluble substances. In materials science, it is often utilized as a solubilizing agent to improve the dispersion of compounds within aqueous solutions, which is critical in formulating consistent and effective mixtures. Research into environmental science employs sodium xylenesulfonate to study its biodegradability and impact on aquatic life, contributing to the understanding of chemical behaviors in wastewater treatment processes. Additionally, its role in enhancing the efficacy of cleaning formulations is examined in industrial research, aiming to optimize the performance of household and industrial cleaning agents. Studies in the field of analytical chemistry also make use of sodium xylenesulfonate to facilitate chromatographic processes, where it aids in the separation of substances for more accurate analysis.


Sodium xylenesulfonate (CAS 1300-72-7) References

  1. p53 induction as a genotoxic test for twenty-five chemicals undergoing in vivo carcinogenicity testing.  |  Duerksen-Hughes, PJ., et al. 1999. Environ Health Perspect. 107: 805-12. PMID: 10504146
  2. The Hydrotrope Action of Sodium Xylenesulfonate on the Solubility of Lecithin.  |  Horváth-Szabó, G., et al. 2001. J Colloid Interface Sci. 236: 52-59. PMID: 11254328
  3. NTP Toxicology and Carcinogenesis Studies of Technical Grade Sodium Xylenesulfonate (CAS No. 1300-72-7) in F344/N Rats and B6C3F1 Mice (Dermal Studies).  |  ,. 1998. Natl Toxicol Program Tech Rep Ser. 464: 1-272. PMID: 12579200
  4. Advanced Fractionation of Kraft Lignin by Aqueous Hydrotropic Solutions.  |  Gaspar, R., et al. 2023. Molecules. 28: PMID: 36677747
  5. Prediction of the carcinogenicity of a second group of organic chemicals undergoing carcinogenicity testing.  |  Zhang, YP., et al. 1996. Environ Health Perspect. 104 Suppl 5: 1045-50. PMID: 8933053
  6. O/W microemulsions and hydrotropes: the coupling action of a hydrotrope  |  Friberg, S. E., Brancewicz, C., & Morrison, D. S. 1994. Langmuir. 10(9): 2945-2949.
  7. Solubilities of 6-Aminopenicillanic Acid and Phenoxyacetic Acid in Hydrotrope Solutions  |  Tavare, N. S., & Jadhav, V. K. 1996. Journal of Chemical & Engineering Data. 41(5): 1196-1202.
  8. Kinetics of formation of vesicles from lecithin/sodium xylenesulfonate micelles from stopped-flow measurements  |  Campbell, S. E., Zhang, Z., Friberg, S. E., & Patel, R. 1998. Langmuir. 14(3): 590-594.
  9. Controlling the size of vesicles prepared from egg lecithin using a hydrotrope  |  Heldt, N., Zhao, J., Friberg, S., Zhang, Z., Slack, G., & Li, Y. 2000. Tetrahedron. 56(36): 6985-6990.
  10. Interpretation of the Activity of a Hydrotrope in Lecithin/Sodium Xylenesulfonate/Water Microemulsions  |  Horváth-Szabó, G., & Friberg, S. E. 2001. Langmuir. 17(2): 278-287.
  11. Extraction of lignin from lignocellulose at atmospheric pressure using alkylbenzenesulfonate ionic liquid  |  Tan, S. S., MacFarlane, D. R., Upfal, J., Edye, L. A., Doherty, W. O., Patti, A. F.,.. & Scott, J. L. 2009. Green Chemistry. 11(3): 339-345.
  12. Synergistic effects in the pyrolysis of phosphorus-based flame-retardants: the role of Si-and N-based compounds  |  Deh, S., Gähr, F., & Buchmeiser, M. R. 2016. Polymer Degradation and Stability. 130: 155-164.
  13. The effect of different pre-treatments to improve delignification of eucalypt stumps in a biorefinery context  |  Gominho, J., Costa, R., Lourenço, A., Neiva, D. M., & Pereira, H. 2019. Bioresource Technology Reports. 6: 89-95.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Sodium xylenesulfonate, 100 g

sc-251063
100 g
$156.00