Salinomycin monosodium salt

Salinomycin monosodium salt (CAS 55721-31-8)

Salinomycin monosodium salt | CAS 55721-31-8 is rated 5.0 out of 5 by 1.
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Application: An antibacterial and coccidiostat compound that shows selective toxicity for Cancer stems cells (CSCs)
CAS Number: 55721-31-8
Purity: ≥85%
Molecular Weight: 774.0
Molecular Formula: C42H70NaO11
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Cancer stems cells (CSCs) are a subpopulation of cells within tumors that drive tumor growth and recurrence. They are resistant to many current cancer treatments. Salinomycin (sodium salt) is an antibacterial and coccidiostat compound that shows selective toxicity for the CSCs that exist as a subpopulation within HMLER breast cancer cells (IC50s = ~24 versus ~90 μM).1 At 8 μM, salinomycin treatment of 4T1 and MCF7Ras breast cancer cell lines results in a ~2-fold and ~3-fold, respective reduction of CSCs relative to controls.1 Treatment of 5 mg/kg salinomycin in mice implanted with SUM159 human breast cancer cells inhibits mammary tumor growth and induces increased epithelial differentiation of tumor cells.

Physical State :
Solid
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Transport :
UN 2811, Class 6.1, Packing group II
PubChem CID :
53487842
MDL Number :
MFCD00167109
SMILES :
CC[C@H]([C@H]1CC[C@@H]([C@@H](O1)[C@@H](C)C([C@H](C)C(=O)[C@H](CC)[C@@H]2[C@H](C[C@H]([C@]3(O2)C=C[C@H]([C@@]4(O3)CC[C@@](O4)(C)[C@H]5CC[C@@]([C@@H](O5)C)(CC)O)O)C)C)O)C)C(=O)[O-].[Na+]

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Dear, Santa Cruz Please can you inform me over the purity of the product salinomycin sc236851?

Asked by: Gerrit
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. Alternatively, please contact our Technical Service Department to inquire about the purity of our most recent lot. Please call our European Support office toll-free at 00800 4573 8000, email europe@scbt.com, or contact us by live chat.
Answered by: Technical Support
Date published: 2017-01-05
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Rated 5 out of 5 by from Salinomycin monosodium salt - 100 mg I bought the above mentioned product few weeks ago. Both the product and its backing was in excellent condition. The service was also great. I am so happy with Santa Cruz Biotechnology product and their service.
Date published: 2017-01-31
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