Molecular structure of Methyl 4-oxobutanoate, CAS Number: 13865-19-5
Methyl 4-oxobutanoate (CAS 13865-19-5)
Application:
Methyl 4-oxobutanoate is a simple aldehyde methyl ester compound
CAS Number:
13865-19-5
Purity:
≥90%
Molecular Weight:
116.12
Molecular Formula:
C5H8O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Methyl 4-oxobutanoate is a useful aldehyde compound for synthesis. This compound contains an aldehyde and a methyl ester with a 1,4-relationship between these functionalities. In a study exploring the asymmetric Henry reaction, Methyl 4-oxobutanoate was reported as a model substrate where it was used to assemble a stereodefined lactam efficiently and with high enantiomeric purity.
Methyl 4-oxobutanoate (CAS 13865-19-5) References
- 5-Hydroxyalkyl derivatives of tert-butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate: diastereoselectivity of the Mukaiyama crossed-aldol-type reaction. | Vallat, O., et al. 2009. Acta Crystallogr C. 65: o171-5. PMID: 19346616
- Asymmetric copper(I)-catalyzed Henry reaction with an aminoindanol-derived bisoxazolidine ligand. | Spangler, KY. and Wolf, C. 2009. Org Lett. 11: 4724-7. PMID: 19743819
- Tryptophanol-derived oxazolopiperidone lactams: identification of a hit compound as NMDA receptor antagonist. | Pereira, NA., et al. 2014. Bioorg Med Chem Lett. 24: 3333-6. PMID: 24974339
- Organocatalytic Approach for Short Asymmetric Synthesis of (R)-Paraconyl Alcohol: Application to the Total Syntheses of IM-2, SCB2, and A-Factor γ-Butyrolactone Autoregulators. | Sarkale, AM., et al. 2018. J Org Chem. 83: 4167-4172. PMID: 29490143
- Synthesis and tyrosinase inhibitory activities of 4-oxobutanoate derivatives of carvacrol and thymol. | Brotzman, N., et al. 2019. Bioorg Med Chem Lett. 29: 56-58. PMID: 30446314
- Stereodivergent Synthesis of 1-Hydroxymethylpyrrolizidine Alkaloids. | Sarkale, AM. and Appayee, C. 2020. Org Lett. 22: 4355-4359. PMID: 32459490
- Diversifying DNA-Tagged Amines by Isocyanide Multicomponent Reactions for DNA-Encoded Library Synthesis. | Willems, S., et al. 2024. ACS Omega. 9: 7719-7724. PMID: 38405463
- Neutral constituents of volatiles in cultured broth of Sporobolomyces odorus | Tahara, S., Fujiwara, K., & Mizutani, J. 1973. Agricultural and biological Chemistry. 37(12): 2855-2861.
- Asymmetric synthesis of indole alkaloids from (L)-tryptophan: formal syntheses of (-)-koumine,(-)-taberpsychine & (-)-koumidine | Bailey, P. D., & McLay, N. R. 1991. Tetrahedron letters. 32(31): 3895-3898.
- Synthesis of benzyl and tert‐butyl 3‐(2‐methoxycarbonylethyl)‐4‐methylpyrrole‐2‐carboxylates from methyl 4‐oxobutanoate | Drinan, M. A., & Lash, T. D. 1994. Journal of heterocyclic chemistry. 31(1): 255-257.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methyl 4-oxobutanoate, 1 g | sc-255287 | 1 g | $297.00 |