Date published: 2025-10-14

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L-Glutamine (CAS 56-85-9)

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Alternate Names:
(S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide
Application:
L-Glutamine is a non-essential amino acid
CAS Number:
56-85-9
Molecular Weight:
146.14
Molecular Formula:
C5H10N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Glutamine is an amino acid that serves as a key component in various research studies, particularly those focusing on cellular metabolism. In cell culture, L-Glutamine is a critical nutrient that supports the growth and viability of a wide array of cell lines by providing a source of energy and serving as a carbon donor for the synthesis of nucleotides. Researchers also utilize L-Glutamine to explore its role in the production of glutathione, a major antioxidant that aids in protecting cells from oxidative stress. Additionally, L-Glutamine is involved in studies of protein synthesis and ammonia detoxification, as it acts as a substrate for the enzyme glutamine synthetase. In metabolic flux analysis, L-Glutamine is monitored to understand its contribution to the anaplerotic pathways, which replenish tricarboxylic acid (TCA) cycle intermediates.


L-Glutamine (CAS 56-85-9) References

  1. L-Glutamine-induced apoptosis in microglia is mediated by mitochondrial dysfunction.  |  Svoboda, N. and Kerschbaum, HH. 2009. Eur J Neurosci. 30: 196-206. PMID: 19614980
  2. L-Glutamine regulates amino acid utilization by intestinal bacteria.  |  Dai, ZL., et al. 2013. Amino Acids. 45: 501-12. PMID: 22451274
  3. Oral L-glutamine administration attenuated cutaneous wound healing in Wistar rats.  |  Goswami, S., et al. 2016. Int Wound J. 13: 116-24. PMID: 24690128
  4. L-glutamine supplementations enhance liver glutamine-glutathione axis and heat shock factor-1 expression in endurance-exercise trained rats.  |  Petry, ÉR., et al. 2015. Int J Sport Nutr Exerc Metab. 25: 188-97. PMID: 25202991
  5. Oral supplementations with L-glutamine or L-alanyl-L-glutamine do not change metabolic alterations induced by long-term high-fat diet in the B6.129F2/J mouse model of insulin resistance.  |  Bock, PM., et al. 2016. Mol Cell Biochem. 411: 351-62. PMID: 26530165
  6. L-Glutamine-assisted synthesis of ZnO oatmeal-like/silver composites as an electrochemical sensor for Pb2+ detection.  |  Mahmoudian, MR., et al. 2019. Anal Bioanal Chem. 411: 517-526. PMID: 30498983
  7. L-glutamine protects mouse brain from ischemic injury via up-regulating heat shock protein 70.  |  Luo, LL., et al. 2019. CNS Neurosci Ther. 25: 1030-1041. PMID: 31218845
  8. The effects of glycine-glutamine dipeptide replaced l-glutamine on bovine parthenogenetic and IVF embryo development.  |  Zuo, Z., et al. 2020. Theriogenology. 141: 82-90. PMID: 31518732
  9. Ultrasound enhanced biosynthesis of L-theanine from L-glutamine and ethylamine by recombinant γ-glutamyltranspeptidase.  |  Xu, L., et al. 2020. Bioresour Technol. 307: 123251. PMID: 32245672
  10. L-glutamine as a T2 exchange contrast agent.  |  Joo, CG., et al. 2020. Magn Reson Med. 84: 2055-2062. PMID: 32406063
  11. Effects of exogenous L-Glutamine as a sole nitrogen source on physiological characteristics and nitrogen use efficiency of poplar.  |  Han, M., et al. 2022. Plant Physiol Biochem. 172: 1-13. PMID: 35007889
  12. Effect of L-Glutamine on Chylomicron Formation and Fat-Induced Activation of Intestinal Mucosal Mast Cells in Sprague-Dawley Rats.  |  He, Y., et al. 2022. Nutrients. 14: PMID: 35565745
  13. L-glutamine inhibits nitric oxide synthesis in bovine venular endothelial cells.  |  Meininger, CJ. and Wu, G. 1997. J Pharmacol Exp Ther. 281: 448-53. PMID: 9103529

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Glutamine, 100 g

sc-391013
100 g
$36.00

L-Glutamine, 250 g

sc-391013C
250 g
$46.00

L-Glutamine, 1 kg

sc-391013A
1 kg
$97.00

L-Glutamine, 5 kg

sc-391013D
5 kg
$372.00

L-Glutamine, 10 kg

sc-391013B
10 kg
$719.00