Date published: 2025-10-14

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Hexanoic acid (CAS 142-62-1)

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Alternate Names:
Acid C6; Caproic acid
Application:
Hexanoic acid is a carboxylic acid used as a building block for biochemical research
CAS Number:
142-62-1
Purity:
98%
Molecular Weight:
116.16
Molecular Formula:
C6H12O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Hexanoic acid is a six-carbon linear saturated fatty acid that functions as a precursor in the biosynthesis of various lipids. It is involved in the regulation of lipid metabolism and energy production within cells. At the molecular level, hexanoic acid can interact with enzymes involved in fatty acid metabolism, such as acyl-CoA synthetase and acyl-CoA dehydrogenase, to modulate their activity. This interaction can impact the rate of fatty acid oxidation and the production of energy within cells. Hexanoic acid can also act as a signaling molecule, influencing gene expression related to lipid metabolism. Its mechanism of action involves binding to specific receptors and initiating intracellular signaling cascades that regulate lipid homeostasis. Hexanoic acid plays a functional role in lipid metabolism and energy production within cells through its interactions with key enzymes and signaling pathways.


Hexanoic acid (CAS 142-62-1) References

  1. Hexanoic acid-induced resistance against Botrytis cinerea in tomato plants.  |  Vicedo, B., et al. 2009. Mol Plant Microbe Interact. 22: 1455-65. PMID: 19810814
  2. A biosynthetic pathway for hexanoic acid production in Kluyveromyces marxianus.  |  Cheon, Y., et al. 2014. J Biotechnol. 182-183: 30-6. PMID: 24768798
  3. Priming of plant resistance by natural compounds. Hexanoic acid as a model.  |  Aranega-Bou, P., et al. 2014. Front Plant Sci. 5: 488. PMID: 25324848
  4. Hexanoic Acid Treatment Prevents Systemic MNSV Movement in Cucumis melo Plants by Priming Callose Deposition Correlating SA and OPDA Accumulation.  |  Fernández-Crespo, E., et al. 2017. Front Plant Sci. 8: 1793. PMID: 29104580
  5. GC-MS Analysis of Short-Chain Fatty Acids in Feces, Cecum Content, and Blood Samples.  |  Hoving, LR., et al. 2018. Methods Mol Biol. 1730: 247-256. PMID: 29363078
  6. Influence of electron acceptors on hexanoic acid production by Clostridium kluyveri.  |  San-Valero, P., et al. 2019. J Environ Manage. 242: 515-521. PMID: 31075646
  7. Bioremediation of Hexanoic Acid and Phenanthrene in Oil Sands Tailings by the Microbial Consortium BioTiger™.  |  Reddy, DO., et al. 2020. Bull Environ Contam Toxicol. 104: 253-258. PMID: 31898751
  8. RIFM fragrance ingredient safety assessment, hexanoic acid, CAS Registry Number 142-62-1.  |  Api, AM., et al. 2020. Food Chem Toxicol. 138 Suppl 1: 111263. PMID: 32199968
  9. RIFM fragrance ingredient safety assessment, hexanoic acid, 6-(acetyloxy)-, ethyl ester, CAS Registry Number 104986-28-9.  |  Api, AM., et al. 2020. Food Chem Toxicol. 141 Suppl 1: 111422. PMID: 32439588
  10. Hexanoic acid: a new potential substitute for copper-based agrochemicals against citrus canker.  |  Caccalano, MN., et al. 2021. J Appl Microbiol. 131: 2488-2499. PMID: 34008224
  11. Genomics analysis of hexanoic acid exposure in Drosophila species.  |  Drum, ZA., et al. 2022. G3 (Bethesda). 12: PMID: 34718544
  12. Effects of hexanoic acid on microbial communities, fermentation, and hygienic quality of corn silages infested with toxigenic fungi.  |  Wang, W., et al. 2022. J Sci Food Agric. 102: 3522-3534. PMID: 34841530
  13. Molecular Basis of Hexanoic Acid Taste in Drosophila melanogaster.  |  Pradhan, RN., et al. 2023. Mol Cells. 46: 451-460. PMID: 37202372

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Hexanoic acid, 2.5 g

sc-215146
2.5 g
$20.00

Hexanoic acid, 100 g

sc-215146A
100 g
$36.00