Date published: 2026-1-6

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Ethyl 2-isopropylacetoacetate (CAS 1522-46-9)

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CAS Number:
1522-46-9
Molecular Weight:
172.22
Molecular Formula:
C9H16O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl 2-isopropylacetoacetate is a b-keto ester compound with an isopropyl substitution at the a-position between the two carbonyls. Ethyl 2-isopropylacetoacetate is potentially useful as in synthetic applications as a precursor to a,a-disubstituted b-keto esters, and the a-Me and a-Et analogs have been used in the preparation of stereodefined a,a-disubstituted amino acids.


Ethyl 2-isopropylacetoacetate (CAS 1522-46-9) References

  1. Asymmetric synthesis of alpha,alpha-disubstituted alpha-amino acids using (S,S)-cyclohexane-1,2-diol as a chiral auxiliary.  |  Tanaka, M., et al. 2001. J Org Chem. 66: 2667-73. PMID: 11304185
  2. Thionation with the reagent combination of phosphorus pentasulfide and hexamethyldisiloxane.  |  Curphey, TJ. 2002. J Org Chem. 67: 6461-73. PMID: 12201768
  3. Identification of 4-quinolone derivatives as inhibitors of reactive oxygen species production from human umbilical vein endothelial cells.  |  Onda, K., et al. 2011. Bioorg Med Chem Lett. 21: 6861-6. PMID: 21963985
  4. Production and sex-pheromonal activity of alkaloid-derived androconial compounds in the danaine butterfly, Parantica sita (Lepidoptera: Nymphalidae: Danainae)  |  Keiichi Honda, Yasuyuki Honda, Junya Matsumoto, Yoshiaki Tsuruta, Wataru Yagi, Hisashi Ômura, Hiroshi Honda. 2016. Biological Journal of the Linnean Society. 119: 1036–1059.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl 2-isopropylacetoacetate, 25 mg

sc-228024
25 mg
$62.00