Dihydrocoumarin A potential epigeenetic process disruptor and Sir2 inhibitor

Dihydrocoumarin (CAS 119-84-6)

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Synonym: 3,4-Dihydro-1-benzopyran-2-one; Benzodihydropyrone; Hydrocoumarin
Application: A potential epigeenetic process disruptor and Sir2 inhibitor
CAS Number: 119-84-6
Purity: ≥98%
Molecular Weight: 148.16
Molecular Formula: C9H8O2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Dihydrocoumarin is a common compound found in sweet clover that has been studied as a disruptor of epigenetic processes in cells. Epigenetic processes control gene expression within a cell and are highly influenced by environmental factors. Epigenomic disruptions change which genes are expressed and to what extent and are not linked to DNA mutations. Dihydrocoumarin has been shown to inhibit the sirtuin deacetylase family, specifically Sir2, SIRT1, and SIRT2.

Physical State :
Liquid
Storage :
Store at room temperature
Melting Point :
24-25° C (lit.)
Boiling Point :
272° C (lit.)
Density :
1.17 g/mL at 25° C
Refractive Index :
n20D 1.556 (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
660
SMILES :
C1CC(=O)OC2=CC=CC=C21

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Certificate of Analysis

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