Date published: 2025-10-3

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D-Cystine (CAS 349-46-2)

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Alternate Names:
(S,S)-3,3′-Dithiobis(2-aminopropionic acid)
CAS Number:
349-46-2
Purity:
≥98%
Molecular Weight:
240.30
Molecular Formula:
C6H12N2O4S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Cystine is primarily researched for its applications in biochemistry and molecular biology, focusing on its role in protein structure and function. This compound is a dimeric amino acid formed by the oxidation of two cysteine molecules, which creates a disulfide bond that is for the stability of many proteins. Studies involving D-Cystine often examine its behavior in redox reactions and its ability to form and maintain disulfide bridges in proteins, which are essential for proper protein folding and function. Additionally, D-Cystine′s involvement in cellular processes such as signaling and regulation is a key area of investigation. Research also explores how modifications of D-Cystine affect biological systems, which helps in understanding cellular responses to oxidative stress and other environmental factors.


D-Cystine (CAS 349-46-2) References

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  2. Double-helical cyclic peptides: design, synthesis, and crystal structure of figure-eight mirror-image conformers of adamantane-constrained cystine-containing cyclic peptide cyclo (Adm-Cyst)(3).  |  Ranganathan, D., et al. 2000. J Org Chem. 65: 4415-22. PMID: 10891146
  3. Thermostable S-alkylcysteine alpha, beta-lyase from a thermophile: purification and properties.  |  Kamitani, H., et al. 1990. Agric Biol Chem. 54: 2069-76. PMID: 1368609
  4. L-CYSTINE REQUIREMENT FOR PRODUCTION OF COXSACKIE B3 VIRUS IN CULTURED MONKEY HEART CELLS.  |  TYNDALL, RL. and LUDWIG, EH. 1963. J Bacteriol. 85: 1339-45. PMID: 14047227
  5. L-cystine inhibits aspartate-beta-semialdehyde dehydrogenase by covalently binding to the essential 135Cys of the enzyme.  |  Alvarez, E., et al. 2004. Biochim Biophys Acta. 1696: 23-9. PMID: 14726201
  6. Comparative species utilization and toxicity of sulfur amino acids.  |  Baker, DH. 2006. J Nutr. 136: 1670S-1675S. PMID: 16702338
  7. Differential effects of endogenous cysteine analogs on peripheral thermal nociception in intact rats.  |  Pathirathna, S., et al. 2006. Pain. 125: 53-64. PMID: 16782275
  8. Dimeric and monomeric surfactants derived from sulfur-containing amino acids.  |  Faustino, CM., et al. 2010. J Colloid Interface Sci. 351: 472-7. PMID: 20800236
  9. Purification and Characterization of Cystine Lyase a from Broccoli Inflorescence.  |  Ukai, K. and Sekiya, J. 1997. Biosci Biotechnol Biochem. 61: 1890-5. PMID: 27396740
  10. The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells.  |  Heinecke, JW., et al. 1987. J Biol Chem. 262: 10098-103. PMID: 3038867
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  12. Penicillin-insensitive incorporation of D-amino acids into cell wall peptidoglycan influences the amount of bound lipoprotein in Escherichia coli.  |  Tsuruoka, T., et al. 1984. J Bacteriol. 160: 889-94. PMID: 6389516
  13. The utilization and safety of isomeric sulfur-containing amino acids in mice.  |  Friedman, M. and Gumbmann, MR. 1984. J Nutr. 114: 2301-10. PMID: 6502274
  14. Amino acids and derivatives of thiazole-4-carboxylic acid as constituents of thiopeptin B.  |  Muramatsu, I., et al. 1977. J Antibiot (Tokyo). 30: 383-7. PMID: 885796
  15. Inactivation of phosphoenolypyruvate carboxykinase (GTP) by liver extracts.  |  Ballard, FJ. and Hopgood, MF. 1976. Biochem J. 154: 717-24. PMID: 942393

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Cystine, 5 g

sc-255056
5 g
$90.00