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3-Mercaptopropionic acid (CAS 107-96-0)

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Alternate Names:
3-Thiopropionic acid
Application:
3-Mercaptopropionic acid is A compound suitable for amino acid analysis by means of OPA.
CAS Number:
107-96-0
Purity:
≥98%
Molecular Weight:
106.14
Molecular Formula:
C3H6O2S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Mercaptopropionic acid is an organic compound. It exists as a colourless liquid that demonstrates solubility in both water and organic solvents. As a sulfur-containing carboxylic acid and a derivative of propionic acid, 3-Mercaptopropionic acid serves as a precursor for the synthesis of various organic compounds, making it invaluable across scientific and industrial applications. In scientific research, this compound finds widespread usage as a reagent in organic synthesis and in the production of proteins and other biomolecules. It also functions as a chelating agent, adept at binding metal ions within aqueous solutions, and plays a vital role as a stabilizing agent in polymer production.


3-Mercaptopropionic acid (CAS 107-96-0) References

  1. 3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters.  |  Kang, J., et al. 2009. Chem Commun (Camb). 407-9. PMID: 19137167
  2. 3-mercaptopropionic acid-induced seizures decrease NR2B expression in Purkinje cells: cyclopentyladenosine effect.  |  Girardi, E., et al. 2010. Cell Mol Neurobiol. 30: 985-90. PMID: 20625810
  3. 3-Mercaptopropionic acid-induced repetitive seizures increase GluN2A expression in rat hippocampus: a potential neuroprotective role of cyclopentyladenosine.  |  Gori, MB. and Girardi, E. 2013. Cell Mol Neurobiol. 33: 803-13. PMID: 23748434
  4. Correlation of 3-mercaptopropionic acid induced seizures and changes in striatal neurotransmitters monitored by microdialysis.  |  Crick, EW., et al. 2014. Eur J Pharm Sci. 57: 25-33. PMID: 24462767
  5. Determination of 3-mercaptopropionic acid by HPLC: A sensitive method for environmental applications.  |  Salgado, P., et al. 2015. J Chromatogr B Analyt Technol Biomed Life Sci. 992: 103-8. PMID: 25966653
  6. New model of pharmacoresistant seizures induced by 3-mercaptopropionic acid in mice.  |  Enrique, A., et al. 2017. Epilepsy Res. 129: 8-16. PMID: 27875747
  7. Colloidal 3-Mercaptopropionic Acid Capped Lead Sulfide Quantum Dots in a Low Boiling Point Solvent.  |  Reinhart, CC. and Johansson, E. 2017. J Am Chem Soc. 139: 5827-5835. PMID: 28394592
  8. Colorimetric determination of As(III) based on 3-mercaptopropionic acid assisted active site and interlayer channel dual-masking of Fe-Co-layered double hydroxides with oxidase-like activity.  |  Xu, X., et al. 2019. Mikrochim Acta. 186: 815. PMID: 31745663
  9. Chromatographic and spectrophometric studies of vanadate (+V) reduction by 3-mercaptopropionic acid.  |  Bura-Nakić, E., et al. 2022. J Inorg Biochem. 230: 111747. PMID: 35151102
  10. A comprehensive investigation of zeolite-rich tuff functionalized with 3-mercaptopropionic acid intercalated green rust for the efficient removal of HgII and CrVI in a binary system.  |  Huang, T., et al. 2022. J Environ Manage. 324: 116344. PMID: 36166867
  11. Overcoming chemoresistance to b-raf inhibitor in melanoma via targeted inhibition of phosphoenolpyruvate carboxykinase1 using 3-mercaptopropionic acid.  |  Ren, M., et al. 2022. Bioengineered. 13: 13571-13586. PMID: 36700470
  12. Green-emitting functionalized silicon nanoparticles as an 'off-on' fluorescence bio-probe for the sensitive and selective detection of mercury (II) and 3-mercaptopropionic acid.  |  Iradukunda, Y., et al. 2023. Talanta. 256: 124322. PMID: 36736269
  13. 3-Mercaptopropionic acid, a potent inhibitor of fatty acid oxidation in rat heart mitochondria.  |  Sabbagh, E., et al. 1985. J Biol Chem. 260: 7337-42. PMID: 3997873
  14. Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase.  |  Horton, RW. and Meldrum, BS. 1973. Br J Pharmacol. 49: 52-63. PMID: 4207045
  15. Cardiovascular effects of 3-mercaptopropionic acid and levels of GABA in regions of the brain of guinea-pigs.  |  Alsip, NL., et al. 1984. Neuropharmacology. 23: 349-57. PMID: 6728126

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Mercaptopropionic acid, 5 g

sc-256523
5 g
$37.00

3-Mercaptopropionic acid, 100 g

sc-256523A
100 g
$39.00