Date published: 2025-9-8

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TGF beta 1 Anticorpo (TB21): sc-52893

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Fichas de dados
  • TGF beta 1 Anticorpo TB21é um anticorpo monoclonal produzido em camundongo IgG1 κ, citado em 102 publicações, fornecido em 100 µg/ml
  • ativado contra TGFβ1 de human origem plaquetária
  • recomendado para a detecção de natural and recombinant TGFβ1, both dimeric and monomeric natural forms under reducing and non reducing conditions de mouse, rat e human origem em
  • See TGF beta 1 (3C11): sc-130348 for additional antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de TGF beta 1 (TB21): sc-52893.
  • m-IgG Fc BP-HRP e m-IgG1 BP- HRP são os reagentes de deteção secundários preferidos para TGF beta 1 Anticorpo (TB21) para aplicações WB and IHC(P). Estes reagentes são agora oferecidos em conjuntos com TGF beta 1 Anticorpo (TB21) (ver informações para encomenda abaixo).

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VEJA TAMBÉM

O anticorpo anti-TGFβ1 (TB21) é um anticorpo monoclonal de cadeia leve IgG1 kappa de ratinho que detecta o TGFβ1 em amostras de camundongo, rato e humano através de aplicações como western blotting (WB), imunoprecipitação (IP), imunofluorescência (IF), imunohistoquímica com secções incluídas em parafina (IHCP) e citometria de fluxo (FCM). O anticorpo anti-TGFβ1 (TB21) está disponível numa forma não conjugada, especificamente concebida para investigadores que estudam o fator de crescimento transformador beta 1, que desempenha um papel crucial na regulação de vários processos celulares, incluindo o crescimento celular, a diferenciação e as respostas imunitárias. O TGFβ1 é secretado principalmente pelas plaquetas e encontra-se na matriz extracelular, onde modula as vias de sinalização celular que regem a reparação dos tecidos e a fibrose. O TGFβ1 sofre várias modificações pós-traducionais, incluindo a glicosilação e a fosforilação, que influenciam significativamente a atividade e a estabilidade. Estas modificações são essenciais para o funcionamento adequado do TGFβ1, afectando as interações com receptores específicos e outras proteínas, o que acaba por ter impacto nos processos de desenvolvimento e nos estados de doença. A forma madura do TGFβ1 só é biologicamente ativa quando dimerizada, o que realça a importância da integridade estrutural para uma sinalização eficaz. Com a capacidade de mediar interações celulares críticas, o TGFβ1 é um interveniente fundamental tanto em processos fisiológicos normais como em condições patológicas, o que faz do anticorpo monoclonal TGFβ1 (TB21) uma ferramenta inestimável para investigar diversos papéis na saúde e na doença.

Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.

Informacoes sobre ordens

Nome do ProdutoNumero de CatalogoUNIDPrecoQdeFAVORITOS

TGF beta 1 Anticorpo (TB21)

sc-52893
100 µg/ml
$316.00

Pacote do TGF beta 1 (TB21): m-IgG Fc BP-HRP

sc-538961
100 µg Ab; 10 µg BP
$354.00

Pacote do TGF beta 1 (TB21): m-IgG1 BP-HRP

sc-541178
100 µg Ab; 20 µg BP
$354.00

Do you know if there is any cross reactivity with horse tissues?

Asked by: Anonymous
Thank you for your question. TGF beta 1 Antibody (TB21): sc-52893 is recommended for detection of natural and recombinant TGFβ1, both dimeric and monomeric natural forms under reducing and non reducing conditions of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM. It has not been evaluated in equine cell or tissue samples.
Answered by: Tech Support Europe
Date published: 2023-08-15

is it possible to use this antibody for Flow Cytometry using a congugate? like Alexa 488.

Asked by: MMPP
Thank you for your question. It would be helpful if you could call us directly at 800-457-3801 ext. 1, allowing for a more interactive discussion of this and other related questions.
Answered by: Blake J
Date published: 2021-09-07

How many slides can this product again by immunohistochemistry

Asked by: Nnnnonn
Thank you for your question. How many slides you can stain with the antibody depends on the conditions used, the amount of antibody you use and the samples, so we can not provide this information. You should be able to stain quite a few with a vial of antibody.
Answered by: Tech Service
Date published: 2020-02-07

What is the total volume provided of TGFβ1 Antibody (TB21): sc-52893?

Asked by: jenni
Each vial contains 100 µg IgG1 in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
Answered by: Technical Support 4
Date published: 2020-02-06
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Rated 4 out of 5 by from Good AntibodyIt works quite well in IHC, the signal is clear in melanoma samples with a concentration of 1:100. We also tested it in WB, we obtained a good signal of the predicted band but we also had some aspecific signals. We tested it at a concentration of 1:1000.
Date published: 2022-10-12
Rated 1 out of 5 by from Did not recognize recombinant human TGFb1I tried this antibody in a western blot against recombinant human TGFb1. This antibody did not recognize the protein whereas another antibody clone did.
Date published: 2018-11-14
Rated 4 out of 5 by from Good antibodyThis antibody worked very well with IHC and IF. Strong signal was seen in both applications but there was some stain present on the blood cells of the tissue.
Date published: 2018-03-01
Rated 3 out of 5 by from weak signalwe got low signal band sometimes,we found it may prolong the exposure time to 10min.or more, in this way we can got the target band a littel stronger.
Date published: 2017-07-15
Rated 5 out of 5 by from Nice antibodyStrong IHC and western blot data; pleased with results
Date published: 2017-01-10
Rated 5 out of 5 by from Versatile AntibodyThis is a well-cited antibody good for a variety of applications in human, mouse, and rat samples.
Date published: 2016-12-21
Rated 4 out of 5 by from WB data published for use in human MSCsWB data published for use in human MSCs. -SCBT Publication Review
Date published: 2015-05-18
Rated 4 out of 5 by from Data published for IHC in human paraffinData published for IHC in human paraffin-embedded skin biopsies. -SCBT Publication Review
Date published: 2015-04-16
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TGF beta 1 Anticorpo (TB21) is rated 3.8 out of 5 by 11.
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