Prostaglandin E2-biotinamide CAS: 363-24-6 (unconjugated)
MF: C35H58N4O6S
MW: 662.9
A biotinylated PGE2 derivative designed to detect PGE2 bound in complexes.

Prostaglandin E2-biotinamide (CAS 363-24-6 (unconjugated))

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 116ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Aplicação Prostaglandin E2-biotinamide is A biotinylated PGE2 derivative designed to detect PGE2 bound in complexes
Numero VAT: 363-24-6 (unconjugated)
Peso Molecular: 662.9
Separar por Funcao: C35H58N4O6S
Informação complementar: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.
* Refere-se a Certificado de Análise para data especifica de lotes (incluindo-se o conteúdo de agua).

Prostaglandin E2-biotinamide is a biotinylated Prostaglandin E2 (PGE2; sc-201225) derivative that is designed to allow PGE2 to be detected in complexes with transmembrane receptors and/or nucleic acid or protein binding partners - an incredibly useful tool in the general elucidation of the mechanism of action of Prostaglandins. PGE2 is the most physiologically abundant eicosanoid, which is produced predominantly from arachidonic acid (sc-200770) by COX and PGES, and exists at some level in nearly all cell types. PGE2 acts on four different receptors termed EP1 through EP4 yielding an astounding array of biological effects; including: potent vasodialation, smooth muscle relaxation, both anti- and proinflammatory activities, stimulates bone resorption, synergizes with LTB4, facilitates replication of AIDS virus, regulates sleep/wake cycle, demonstrates thermoregulatory action in the CNS, induces LHRH release from rat median eminence, demonstrates a protective effect on gastric mucosa, and regulates renal hemodynamics and sodium excretion.


Referencias

1. Richardson, P.D., et al. 1976. Br. J. Pharmacol. 57: 581-588. PMID: 963344
2. Raisz, L.G., et al. 1977. Nature. 267: 532-534. PMID: 876371
3. Miller, T.A., 1983. Am. J. Physiol. 245: G601-G623. PMID: 6195926
4. Kuno, S., et al. 1986. Proc. Natl. Acad. Sci. U.S.A. 83: 3487-3490. PMID: 3010301
5. Kuno, S., et al. 1986. Proc. Natl. Acad. Sci. U.S.A. 83: 2682-2683. PMID: 3458226
6. Archer, C.B., et al. 1987. Prostaglandins. 33: 799-805. PMID: 2823313
7. Hayaishi, O. 1988. J. Biol. Chem. 263: 14593-14596. PMID: 3049580
8. Raud, J., et al. 1988. Proc. Natl. Acad. Sci. U.S.A. 85: 2315-2319. PMID: 2451246
9. Long, C.R., et al. 1990. Prostaglandins. 40: 591-601. PMID: 2093936
10. Christman, J.W., et al. 1991. Prostaglandins. 41: 251-262. PMID: 1852897
11. Gerozissis, K., et al. 1991. Prostaglandins. 41: 345-357. PMID: 1871376

Formulação :
A solution in ethanol
Estado físico :
Liquid
Manutencao :
Store at -20° C
Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.
Transporte :
UN 1170, Class 3, Packing group II
SMILES :
CCCCCC(O) /C=C/[[email protected]] 1C(O) CC(=O) C1C/C=C\CCCC(=O) NCCCCCNC(=O) CCCCC1SCC2NC(=O) NC12

Baixar SDS (MSDS)

Certificado de Análise

É necessário o Adobe Acrobat Reader para visualizar corretamente,
imprimir e comentar os documentos PDF

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 104ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 6ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

A Santa Cruz Biotecnologia, Inc. é a líder mundial no desenvolvimento de produtos para o mercado de pesquisa biomédica. Ligue para nós ligação gratuita 1-800-457-3801..
Direito de Reprodução© 2007-2021 Santa Cruz Biotechnology, Inc. Todos os direitos reservados. "Santa Cruz Biotechnology", Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", "EZ Touch" são marcas registradas da Santa Cruz Biotechnology, Inc. Todas as marcas registradas são propriedade dos seus respectivos donos.