Pifithrin-μ (CAS 64984-31-2)
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Pifithrin-μ is a cell-permeable sulfonamide inhibitor of p53 binding and an anti-apoptotic. Direct inhibition of p53 binding to mitochondria as well as to Bcl-xL and Bcl-2 proteins by Pifithrin-mu has been observed. Pifithrin-mu selectively inhibits p53 translocation to mitochondria without affecting the transactivation function of p53. Pifithrin-mu may act to reduce gamma-radiation induced cell death in vitro. Unlike pifithrin-alpha (sc-45050), pifithrin-mu targets only the mitochondrial branch of the p53 pathway without affecting the important transcriptional functions of p53. Pifithrin-mu selectively inhibits HSP 70 (heat shock protein 70) activity. Pifithrin-µ is an artificial substance extensively utilized in diverse scientific investigations. This compound exhibits remarkable versatility, enabling the exploration of numerous biological activities, such as protein-protein interactions, enzyme-substrate interactions, and receptor-ligand interactions.
Pifithrin-μ (CAS 64984-31-2) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pifithrin-μ, 10 mg | sc-203195 | 10 mg | $130.00 | |||
Pifithrin-μ, 50 mg | sc-203195A | 50 mg | $379.00 |