Anti-MIS Anticorpo B-11é um anticorpo monoclonal produzido em camundongo IgG1 κ MIS anticorpo, citado em 8 publicações, fornecido em 200 µg/ml
específico para um epítopo mapeado entre os aminoácidos541-560 no C-terminus de MIS de human origem
Anti-MIS Anticorpo (B-11) é recomendado para a detecção de precursor and mature MIS de mouse, rat e human origem em WB, IP, IF e ELISA; Reage também com outras espécies, incluindo and equine, canine, bovine and porcine
Anti-MIS Antibody (B-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de MIS (B-11): sc-166752.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for MIS Antibody (B-11) for WB applications. These reagents are now offered in bundles with MIS Antibody (B-11) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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MIS Antibody (B-11) is a high quality monoclonal MIS antibody (also designated Müllerian inhibiting factor (MIF) antibody, anti-Müllerian hormone (AMH) antibody, Müllerian-inhibiting hormone (MIH) antibody, TGF-beta (transforming growth factor-beta) superfamily secreted ligand antibody, anti-Mullerian hormone receptor type 2 (AMHR2) ligand antibody, folliculogenesis hormone antibody, or inhibin and activin-related glycoprotein hormone antibody) suitable for the detection of the MIS protein of mouse, rat and human origin. MIS Antibody (B-11) is available as both the non-conjugated anti-MIS antibody form, as well as multiple conjugated forms of anti-MIS antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The transforming growth factor β (TGFβ) superfamily is composed of numerous growth and differentiation factors, including TGFβ1-3, Mullerian inhibiting substance (MIS), growth/differentiation factor (GDF) 1-9, bone morphogenic protein (BMP) 2-8, glial cell line-derived neurotrophic factor (GDNF), Inhibin α, β-A, β-B and β-C, Lefty and Nodal. Members of the TGFβ superfamily are involved in embryonic development and adult tissue homeostasis. The MIS glycoprotein is produced by the sertoli cells of the testis. Fetal testis produce both MIS and testosterone, the presence of which result in male offspring. Absence of MIS and testosterone in a developing fetus results in the induction of Mullerian duct differentiation, and Wolffian duct development is not induced. Testosterone induces the differentiation of the Wolffian ducts whereas MIS causes regression of the Muellerian duct. MIS inhibits the growth of tumors derived from tissues of Muellerian duct origin. MIS can also inhibit the autophosphorylation of the EGF receptor in vitro. Defects in anti-muellerian hormone are the cause of persistent Muellerian duct syndrome type I (PMDS-1). PMDS-1 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn