LXR alpha/beta/NR1H3/NR1H2 antibody (G-10) is a mouse IgG1 κ monoclonal LXRα/β antibody (also called LXRα/β antibody) that detects LXRα and LXRβ of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. The LXR alpha/beta/NR1H3/NR1H2 (G-10) antibody is available as an unconjugated anti-LXRα/β antibody, as well as in various conjugated forms of anti-LXRα/β antibody, including agarose, HRP, PE, FITC and various Alexa Fluor® conjugates. Retinoids are metabolites of vitamin A (retinol) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. The cooperation of the hepatic X receptors (LXRs) α and β and the retinoic X receptor (RXR) modulates the expression of several genes involved in lipid metabolism in hepatocytes and macrophages. RXR is the 9-cis retinoic acid receptor and dimerizes with VDR, TR, PPAR and several other novel receptors, including the hepatic X receptors LXRα (also known as RLD-1), LXRβ and FXR. FXR and LXR fall into a category of proteins called "orphan receptors" due to the lack of a defined function and, in the case of LXR, the lack of a defined fixative. The LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid. LXRα and LXRβ share considerable sequence homology and various functions, respond to the same endogenous and synthetic fixatives and play critical roles in maintaining lipid homeostasis. LXRβ is ubiquitously expressed and enriched in tissues of neuronal and endocrine origin.
Alexa Fluor® é uma marca comercial da Molecular Probes Inc., OR., EUA
LI-COR® e Odyssey® são marcas registadas da LI-COR Biosciences
Informacoes sobre ordens
Nome do Produto | Numero de Catalogo | UNID | Preco | Qde | FAVORITOS | |
LXR alpha/beta/NR1H3/NR1H2 Anticorpo (H-7) | sc-377260 | 200 µg/ml | $316.00 | |||
Pacote do LXR alpha/beta/NR1H3/NR1H2 (H-7): m-IgGκ BP-HRP | sc-523253 | 200 µg Ab, 40 µg BP | $354.00 | |||
LXR alpha/beta/NR1H3/NR1H2 Anticorpo (H-7) X | sc-377260 X | 200 µg/0.1 ml | $316.00 | |||
LXR alpha/beta/NR1H3/NR1H2 Anticorpo (H-7) AC | sc-377260 AC | 500 µg/ml, 25% agarose | $416.00 | |||
LXR alpha/beta/NR1H3/NR1H2 Anticorpo (H-7) HRP | sc-377260 HRP | 200 µg/ml | $316.00 | |||
LXR alpha/beta/NR1H3/NR1H2 Anticorpo (H-7) FITC | sc-377260 FITC | 200 µg/ml | $330.00 | |||
LXR alpha/beta/NR1H3/NR1H2 Anticorpo (H-7) PE | sc-377260 PE | 200 µg/ml | $343.00 | |||
LXR alpha/beta/NR1H3/NR1H2 Anticorpo (H-7) Alexa Fluor® 488 | sc-377260 AF488 | 200 µg/ml | $357.00 | |||
LXR alpha/beta/NR1H3/NR1H2 Anticorpo (H-7) Alexa Fluor® 546 | sc-377260 AF546 | 200 µg/ml | $357.00 | |||
LXR alpha/beta/NR1H3/NR1H2 Anticorpo (H-7) Alexa Fluor® 594 | sc-377260 AF594 | 200 µg/ml | $357.00 | |||
LXR alpha/beta/NR1H3/NR1H2 Anticorpo (H-7) Alexa Fluor® 647 | sc-377260 AF647 | 200 µg/ml | $357.00 | |||
LXR alpha/beta/NR1H3/NR1H2 Anticorpo (H-7) Alexa Fluor® 680 | sc-377260 AF680 | 200 µg/ml | $357.00 | |||
LXR alpha/beta/NR1H3/NR1H2 Anticorpo (H-7) Alexa Fluor® 790 | sc-377260 AF790 | 200 µg/ml | $357.00 | |||
LXR alpha/beta/NR1H3/NR1H2 (H-7) peptídeo neutralizante | sc-377260 P | 100 µg/0.5 ml | $68.00 |