HAI-1 Antibody (C-4): sc-137160

HAI-1 Antibody (C-4) is a mouse monoclonal IgG2b antibody that detects hepatocyte growth factor activator inhibitor 1 (HAI-1) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HAI-1 plays a crucial role in regulating hepatocyte growth factor activator (HGFAC) activity, which is essential for tissue repair and regeneration following injury. By inhibiting HGFAC, HAI-1 helps control the proteolytic activation of hepatocyte growth factor (HGF), thereby modulating cellular responses to damage and promoting healing processes. HAI-1 is predominantly expressed in various human tissues, including placenta, kidney, pancreas, prostate, and small intestine, highlighting HAI-1′s importance in both normal physiology and pathological conditions. HAI-1 is produced in membrane-associated forms and secreted as a proteolytically truncated active protein, which underscores HAI-1′s dynamic role in cellular signaling and tissue homeostasis. Anti-HAI-1 antibody (C-4) is an invaluable tool for researchers investigating tissue repair mechanisms and regulatory pathways involved in HGF activation, providing insights into potential therapeutic targets for conditions associated with tissue damage and regeneration.

The preferred HAI-1 antibody is HAI-1 Antibody (H-1): sc-137159.