H2-I/Eκ Antibody (5K42): sc-71204
- H2-I/Eκ Antibody (5K42) is a mouse monoclonal IgG2a provided at 100 µg/ml
- raised against C3H skin graft and splenocytes of mouse origin
- recommended for detection of H2-I/Eκ alloantigen on cells of the H-2r haplotype of mouse origin by FCM; non cross-reactive with H2-d and H2-p haplotypes
- available conjugated to phycoerythrin for IF, IHC(P) and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for H2-I/Eκ Antibody (5K42). This work is in progress.
H2-I/Eκ Antibody (5K42) is a mouse monoclonal IgG2a light chain antibody that detects H2-I/Eκ in mouse samples through flow cytometry (FCM). H2-I/Eκ is a crucial component of the major histocompatibility complex (MHC) class II molecules, which play a vital role in the immune response by presenting processed antigens to CD4+ T lymphocytes. This interaction is essential for the activation of helper T cells, which subsequently orchestrate the immune response by stimulating B cells and cytotoxic T cells. The structure of H2-I/Eκ, consisting of an alpha chain and a beta chain, allows for effective binding to a diverse array of peptide antigens, thus ensuring a robust immune surveillance mechanism. The proper functioning of MHC class II molecules is critical for the immune system′s ability to distinguish between self and non-self, making H2-I/Eκ an important target for research in immunology and potential therapeutic applications. Anti-H2-I/Eκ antibody (5K42) is ideal for studies focused on immune responses, antigen presentation, and T cell activation in mouse models.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
H2-I/Eκ Antibody (5K42) | sc-71204 | 100 µg/ml | $322.00 | |||
H2-I/Eκ Antibody (5K42) PE | sc-71204 PE | 100 tests in 2 ml | $349.00 |