Anti-FEZF1 Anticorpo F-4é um anticorpo monoclonal produzido em camundongo IgG1 κ FEZF1 anticorpo, citado em 1 publicações, fornecido em 200 µg/ml
Produzido contra aminoácidos 74-262 mapeamento dentro de uma região interna deFEZF1 de human origem
FEZF1 Anticorpo (F-4) é recomendado para a detecção de FEZF1 of human origin by WB, IP, IF and ELISA
Anti-FEZF1 Antibody (F-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de FEZF1 (F-4): sc-515487.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FEZF1 Antibody (F-4) for WB applications. These reagents are now offered in bundles with FEZF1 Antibody (F-4) (see ordering information below).
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FEZF1 Antibody (F-4) is a high quality monoclonal FEZF1 antibody (also designated FEZF1 antibody) suitable for the detection of the FEZF1 protein of human origin. FEZF1 Antibody (F-4) is available as both the non-conjugated anti-FEZF1 antibody form, as well as multiple conjugated forms of anti-FEZF1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Olfactory sensory neurons contain olfactory receptors, which are G protein-coupled receptor proteins that localize to the cilia and display affinity for and bind to a variety of odor molecules. Olfactory neurons send their axons from the olfactory epithelium to the olfactory bulb, which is covered by the CNS basal lamina. FEZF1 (Fez family zinc finger protein 1), also known as Forebrain Embryonic Zinc Finger and Zinc finger protein 312B, is a 475 amino acid nuclear protein that is expressed in the olfactory epithelium and hypothalamus of mice. In FEZF1-deficient mice, axons of olfactory neurons do not reach the olfactory bulb, suggesting that FEXF1 is required for the penetration of olfactory axons though the basal lamina before innervation of the olfactory bulb. When FEZF1 translocates to the nucleus, it induces KRAS overexpression, resulting in activation of ERK-signaling. Overexpression of FEZF1 leads to accelerated proliferation in cultured cells and increased tumor mass in mice. There are three isoforms of FEZF1 that are produced as a result of alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn