Dia 2 Anticorpo C-12é um anticorpo monoclonal produzido em camundongo IgG2b (kappa light chain) fornecido em 200 µg/ml
específico para um epítopo mapeado entre os aminoácidos 48-69 dentro de uma região interna de Dia 2 de human origem
recomendado para a detecção deDia 2 (also designated mDia3 of mouse origin) of mouse, rat and human origin de mouse, rat, human e avian de origem WB, IP, IF e ELISA; reage também com outras espécies, incluindo bovine and avian
peptídeo para bloqueio, sc-393499 P
Veja m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), os nossos produtos recombinantes altamente recomendados substituto dos reagentes IgG anti-camundongo secundários convencionais.
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Animal Health Prescription Item
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Labware ships FedEx Ground free of charge to the contiguous US
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Dia 2, also known as DIAPH2 (diaphanous homolog 2), DRF2 or mDia3 of mouse origin, is a mammalian homolog of the Drosophila diaphanous gene, and belongs to a family of formin homology (FH) proteins which are characterized by having tandemly aligned FH1 (formin homology 1) and FH2 (formin homology 2) domains in their carboxy terminal regions. Dia 2 contains a DAD (diaphanous autoregulatory) domain, which is involved in the elongation of actin filaments, and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain, which interacts with the DAD domain via autoinhibitory interactions to regulate the activation of Dia 2. Expressed in testis and ovary, Dia 2 may be involved in oogenesis. Defects to the gene encoding Dia 2 have been implicated in premature ovarian failure type 2A, a disorder characterized by decreased ovarian function. Dia 2 exists as three alternatively spliced isoforms.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.